Navigation Links
American Chemical Society's weekly PressPac -- May 27, 2009
Date:5/31/2009

roperties of Silver Nanoparticles"

DOWNLOAD FULL TEXT ARTICLE: http://pubs.acs.org/stoken/presspac/presspac/full/10.1021/nn900277t

CONTACT:
Debabrata Dash, M.D., Ph.D., D.Sc.
Professor and Head
Department of Biochemistry
Institute of Medical Sciences
Banaras Hindu University
Varanasi, India
Phone: 0091-93369-10665
Email: ddass@satyam.net.in


ARTICLE #3 FOR IMMEDIATE RELEASE

"Gene silencing" may improve treatment of a deadly complication of liver disease
Molecular Pharmaceutics

A technique that "silences," or turns off, genes shows promise as a potential new treatment for liver fibrosis the disease that leads to cirrhosis scientists in Tennessee are reporting. Their study is scheduled for the June 1 issue of ACS' Molecular Pharmaceutics, a bi-monthly journal. Cirrhosis is the 12th leading cause of death in the United States.

Ram Mahato and colleagues note that fibrosis involves build-up of scar tissue in the liver from chronic liver damage caused by hepatitis, alcohol abuse, toxins, or other factors. Advanced fibrosis can lead to cirrhosis, a condition in which the liver becomes so severely damaged that patients may require a transplant. There is no effective treatment, and patients urgently need new medications. Scientists believe one may emerge from the fascinating discovery that a protein called TGF-beta 1 triggers liver inflammation and that blocking the protein may help.

The researchers designed 10 chemically synthesized substances, termed siRNAs, with the ability to block or "silence" the TGF-beta 1 gene in the liver. When put into rat liver cells, the "gene silencers" decreased levels of type 1 collagen whose excessive production leads to fibrosis, as well as two other substances known to trig
'/>"/>

Contact: Michael Woods
m_woods@acs.org
202-872-6293
American Chemical Society
Source:Eurekalert  

Page: 1 2 3 4 5 6

Related biology news :

1. From alarmed to dismissive: The six ways Americans view global warming
2. American Chemical Societys Weekly PressPac -- May 20, 2009
3. Tips from the American Journal of Pathology
4. American Chemical Societys Weekly PressPac -- May 13, 2009
5. American College of Medical Genetics affirms importance of newborn screening dried blood spots
6. American Chemical Societys weekly PressPac -- May 6, 2009
7. American Chemical Societys weekly PressPac -- April 29, 2009
8. Native Americans descended from a single ancestral group, DNA study confirms
9. American Chemical Societys Weekly PressPac -- April 22, 2009
10. University of Texas at Austin engineer elected to American Academy of Arts and Sciences
11. Springer partners with the American Society for Biochemistry and Molecular Biology
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
American Chemical Society's weekly PressPac -- May 27, 2009
(Date:4/2/2015)... HAMBURG, Germany , April 2, 2015 /PRNewswire/ ... ten fingerprint tests DERMALOG by far outperforms the ... While always maintaining high accuracy, the system is ... second. Hence, the speed proves up to be ... 40% faster than its runner-up performance. ...
(Date:4/1/2015)... 2015   Medisafe ™, the leading global medication ... iOS and Android smartphones and tablets, ... the platform to allow patients to track and correlate ... time, patients will be able to visualize in real-time ... biometrics, such as glucose levels and blood pressure. ...
(Date:3/24/2015)... --Research and Markets ( http://www.researchandmarkets.com/research/hdgz7h/global_iris ) has ... Market 2015-2019" report to their offering. ... grow at a CAGR of 23.5 percent over the ... scenario and the growth prospects of the Global Iris ... market size, the report considers the revenue generated from ...
Breaking Biology News(10 mins):DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 3Medisafe Announces Launch of Biometric Integration, Enabling Patients to Stay Adherent to Their Meds and See Tangible Health Results 2Global Iris Recognition Market 2015-2019 with 3M Cogent, Bioenable Technologies, Cross Match Technology, Iris ID Systems & Safran Dominating 2
... lead to infertility. , Researchers at the University of Illinois ... detailed in the Proceedings of the National Academy of Sciences ... present in the uterus for pregnancy to occur. The study ... Without it, they say, an embryo cannot survive in uterine ...
... are biologically flawed. But they don't agree about what ... the basis for therapeutic cloning. , Also known ... promising approach to create individually customized cellular therapies for ... humans, it begins with stem cells derived from a ...
... estimated 7 million lives, according to the World Health ... behind this complex disease. Now, however, they have a ... In a four-year study published in the January 15 ... at The Institute for Genomic Research (TIGR) and the ...
Cached Biology News:Absence of critical protein linked to infertility 2Cloned stem cells prove identical to fertilized stem cells 2Cloned stem cells prove identical to fertilized stem cells 3Oh, rats! Designer animals reveal possible heart disease genes 2
(Date:4/28/2015)... BARBARA, CALIFORNIA (PRWEB) April 28, 2015 ... consulting firm in the life sciences industry, is proud ... Validate Salesforce and Move Your GxP Processes to the ... organizations are realizing the huge potential and power of ... life sciences organizations worry that data in a cloud ...
(Date:4/28/2015)... 2015 CIRTEC Medical Systems, ... services for complex Class III implantable devices ... to develop a new 35,000 sq. ft. advanced ... has a long history of working with world’s ... breakthrough neurostimulation, heart assistance, drug delivery and smart ...
(Date:4/28/2015)... (PRWEB) April 28, 2015 The Pistoia ... that work together to lower barriers to innovation in ... Mapping project. , The Ontologies Mapping project has ... best practices for ontology management in life sciences R&D. ... set of standardized guidelines, tools and services to enable ...
(Date:4/28/2015)... CA (PRWEB) April 28, 2015 According ... more than 450,000 patients receive medical treatment from burn ... management of burn injury, extensive formation of scars with ... these burn patients for which there is no adequate ... that prevent normal movement and can cause permanent deformity. ...
Breaking Biology Technology:USDM Life Sciences Partners with Salesforce.com for Webinar on How Life Sciences Organizations Can Move GxP Processes to the Cloud 2CIRTEC Medical Systems Expands Capacity with New Advanced Manufacturing Facility 2Pistoia Alliance Announces Start of Ontologies Mapping Project 2Synedgen Burn Treatment Results Presented at Premier Wound Conference 2Synedgen Burn Treatment Results Presented at Premier Wound Conference 3
... venture capital firm, hopes to make waves in ... technology companies. Also, state Assembly Republicans moved to ... studies that require destroying embryos, and the state ... Original air date: Saturday, April 16, 2005 ...
... featured speaker at the Digital Healthcare Conference 2005 ... decade, technology applied to medical records and other information has ... to more common usage. At the Marshfield Clinic , ... hands by the time medical informatics associations and journals began ...
... comes to flexible work practices women are the proverbial canaries ... many corporate career tracks is any indication, the air must ... " On Ramps and Off Ramps: Keeping Talented Women on ... The Center for Work-Life Policy and Carolyn Buck Luce of ...
Cached Biology Technology:Carl Christensen says Marshfield Clinic's history gives it an IT edge 2Carl Christensen says Marshfield Clinic's history gives it an IT edge 3Carl Christensen says Marshfield Clinic's history gives it an IT edge 4Are women opting out or shut out from career tracks? 2Are women opting out or shut out from career tracks? 3Are women opting out or shut out from career tracks? 4
The Trans-Blot Plus gel and cassette assembly tray is used to hold the Trans-Blot Plus gel holder cassette, buffer, and other materials for the gel and membrane sandwich during their assembly....
... mini IEF cell is an apparatus dedicated ... polyacrylamide or agarose slab gels. The cell ... electrodes, casting tray, 5 glass plates, 50 ... 5 sample templates, and instructions. Dimensions are ...
... FXP is the latest entry in the Biomek ... accuracy and increased robustness, it can meet the ... be configured with either one or two pipetting ... FXP sets the standard for flexible laboratory solutions ...
... range of next-generation features into a small-footprint ... for flexible laboratory solutions. It puts every ... dilution, dispensing, and integrations into a ... flexible as it is efficient and economical. ...
Biology Products: