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American Chemical Society's weekly PressPac -- Jan. 2, 2008

discovered benzene in some beverages and reformulated those products. In 2005, the substance again was found in some beverages, likely because new manufacturers were unaware of the problem, the study says. Some manufacturers also have added vitamin C to drinks in response to consumers desire for healthier products.

The study found that product formulation, shelf-life, and storage conditions were important factors affecting benzene formation. The report also describes the in-house validation of FDAs analytical method for determining benzene in beverages. JS

ARTICLE #2 FOR IMMEDIATE RELEASE Survey Results of Benzene in Soft Drinks and Other Beverages by Headspace Gas Chromatography/Mass Spectrometry


Patricia Nyman
U.S. Food and Drug Administration
College Park, Md. 20740
Phone: 301-436-1679


Toward solving the mystery of idiosyncratic drug reactions
Chemical Research in Toxicology

A mysterious and unpredictable group of side effects from modern medications called idiosyncratic drug reactions (IDRs) likely will persist as a major health care problem unless there is a dramatic increase in research funding, according to a 20-year review of research in the field scheduled for the January issue of ACS Chemical Research in Toxicology, a monthly journal.

The review, by Jack Uetrecht, defines IDRs as reactions that happen unexpectedly and with no obvious connection to the known effects of

Contact: Michael Woods
American Chemical Society

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American Chemical Society's weekly PressPac -- Jan. 2, 2008
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