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American Chemical Society's weekly PressPac -- Jan. 14, 2009

Innovative analytical methodology combining micro-X-ray Diffraction, Scanning Electron Microscopy-based mineral maps and Diffuse Reflectance Infrared fourier Transform Spectroscopy to characterize archaeological artifacts"


Carolina Cardell, Ph.D.
University of Granada
Granada, Spain 18071
Phone: +34 958242725
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Advance toward first saliva test for Type 2 diabetes
Journal of Proteome Research

Scientists in Oregon and India are reporting an advance toward developing the first saliva test to diagnose and monitor effectiveness of treatment for Type 2 diabetes. Their report was published in the Jan. 2 issue of ACS' Journal of Proteome Research. The number of cases of that disease (18 million in the United States alone) has doubled during the last 30 years in parallel with the epidemic of obesity. Researchers say their work represents the first comprehensive description of the proteins in the saliva of patients with Type 2 diabetes, also called non-insulin dependent diabetes.

In the study, Paturi V. Rao and colleagues note that early diagnosis and effective treatment is critical for preventing the disease's complications, including loss of vision, nerve damage, and kidney damage. One important barrier is the need for sometimes-painful needle sticks to draw blood for tests. The discomfort can discourage patients from properly monitoring their blood sugar levels, the scientists say.

The researchers analyzed saliva samples from individuals with and without Type 2 diabetes for protein biomarkers of diabetes. They identified 65 proteins that appeared twice as

Contact: Michael Woods
American Chemical Society

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