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American Chemical Society's Weekly PressPac - Oct. 10, 2007
Date:10/15/2007

oved bone density and strength in the lab rats.

ARTICLE #2 FOR IMMEDIATE RELEASE Substituted 6-(1-Pyrrolidine) quinolin-2(1H)-ones as Novel Selective Androgen Receptor Modulators

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CONTACT:
Arjan van Oeveren, Ph.D.
Discovery Research, Ligand Pharmaceuticals Inc.
San Diego, Calif. 92121
Phone: 858-550-7870
Fax: 858-550-7249
E-mail: avanoeveren@ligand.com

ARTICLE #3 FOR IMMEDIATE RELEASE

Early detection of human papilloma and other viral infections
Analytical Chemistry

Scientists in Iowa are reporting development of a new, amazingly sensitive method for identifying the earliest stages of infection with human papilloma virus (HPV), a common virus that can increase the risk of cervical cancer in women. The test also has the potential for early identification of infection with other so-called DNA viruses, which cause a range of diseases that includes genital herpes and hepatitis. Their report is scheduled for the Nov. 1 issue of ACS Analytical Chemistry, a semi-monthly journal.

In the study, Edward S. Yeung and colleagues point out that the most sensitive existing test for viral infections has drawbacks. That test is the Nobel Prize-winning polymerase chain reaction (PCR), used to detect DNA in settings ranging from medical labs to crime scenes. PCR requires an initial step in which scientists amplify, or copy, a DNA sample a thousand-fold before virus detection can begin. However, amplification increases the risk of false-positives and false-negatives, especially when a sample h
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Contact: Michael Woods
m_woods@acs.org
202-872-4400
American Chemical Society
Source:Eurekalert

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