Navigation Links
American Chemical Society's Weekly PressPac -- July 16, 2008
Date:7/21/2008

ARTICLE #1 FOR IMMEDIATE RELEASE

"Snow flea antifreeze protein" could help improve organ preservation
Journal of the American Chemical Society

Scientists in Illinois and Pennsylvania are reporting development of a way to make the antifreeze protein that enables billions of Canadian snow fleas to survive frigid winter temperatures. Their laboratory-produced first-of-a-kind proteins could have practical uses in extending the storage life of donor organs and tissues for human transplantation, the researchers indicate in a report scheduled for the July 9 issue of the Journal of the American Chemical Society, a weekly publication.

In the study, Stephen B. H. Kent and colleagues point out that scientists have tried for years to decipher the molecular structure and produce from chemicals in a laboratory the so-called "snow flea antifreeze protein (sfAFP)." Those steps are critical for obtaining larger amounts of the protein, which exists naturally in only minute quantities in snow fleas. The larger synthetic quantities can be used for further research and potential medical and commercial uses, they say.

The researchers made synthetic sfAFP, and showed that it has the same activity as the natural protein. They also produced variants, including one form of sfAFP with a molecular architecture that is the reverse, or "mirror image," of natural sfAFP and different from any other protein found in living things on Earth. The mirror-image form of sfAFP appears less likely to trigger harmful antibodies and more resistant to destruction by natural enzymes, making it potentially more effective than the native form for use in organ and tissue preservation, the scientists note. "Our most significant advance was the use of the two mirror image forms of the protein to determine the previously unknown crystal structure of this unique protein," said Kent. "That is a first in the history of protein X-ray crystallography
'/>"/>

Contact: Michael Woods
m_woods@acs.org
202-872-4400
American Chemical Society
Source:Eurekalert  

Page: 1 2 3 4 5 6 7 8 9

Related biology news :

1. American Chemical Societys Weekly PressPac -- Aug. 8, 2007
2. Understanding hypertension in African Americans proves elusive
3. Tips from the Journals of the American Society for Microbiology
4. American Chemical Societys Weekly PressPac -- Aug. 15, 2007
5. American College of Medical Genetics responds to new FDA labeling decision for warfarin
6. American Chemical Societys Weekly Press Pac
7. Highlights from the September 2007 Journal of the American Dietetic Association
8. American Chemical Societys Weekly Presspac -- Aug. 29, 2007
9. Report: African, Asian, Latin American farm animals face extinction
10. American Chemical Society calls green chemistry bill a smart step
11. Challenges remain in reintroducing American chestnut
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
American Chemical Society's Weekly PressPac -- July 16, 2008
(Date:7/11/2014)... international team of researchers, including scientists from the Max ... a reported a major step in understanding photosynthesis, the ... maintains the oxygen in its atmosphere and which is ... earth. , The researchers report the first direct ... namely the step in which a specific protein complex, ...
(Date:7/11/2014)... of kidney injury related to the use of hydroxyethyl ... HES molecules, according to a report in Anesthesia ... Research Society (IARS). , The "total mass of HES ... human renal proximal tubule cells (PTCs), concludes the laboratory ... Hospital Wrzburg, Austria. Other factorssuch as differences in ...
(Date:7/11/2014)... normal circumstances, astrocytes participate in normal physiological ... exhibit therapeutic and repairing effects on brain ... found that nerve cells differentiated from adipose-derived ... viability, which produces influences on subsequent studies ... Hospital, Hebei United University, China demonstrated that ...
Breaking Biology News(10 mins):A first direct glimpse of photosynthesis in action 2In lab studies, hydroxyethyl starch has direct harmful effects on kidney cells 2
... in the equatorial Pacific by the end of the century, ... study shows that climate change could cause ocean currents to ... of islands right on the equator. Those islands include ... of Kiribati. This low-lying country is at risk from sea-level ...
... New research published online in the FASEB ... 5-lipoxygenase, plays a key role in cell death induced ... likely help prevent or lessen the severity of immune ... space conditions initiate health problems that mimic the aging ...
... going on in DPR Korea than rocket science: local people ... their food supply through agroforestry. This is according to a ... How participatory agroforestry restored land and secured the food supply ... that in DPR Korea a bottomup participatory process of developing ...
Cached Biology News:Global warming refuge discovered near at-risk Pacific island nation of Kiribati 2Global warming refuge discovered near at-risk Pacific island nation of Kiribati 3Global warming refuge discovered near at-risk Pacific island nation of Kiribati 4Scientists discover enzyme that could slow part of the aging process in astronauts -- and the elderly 2Agroforestry is not rocket science but it might save DPR Korea 2Agroforestry is not rocket science but it might save DPR Korea 3
(Date:7/11/2014)... -- EPFL and the University of  Geneva ... John P. Donoghue . The American neuroscientist is to ... The new Wyss Center for Bio- and ... , has named as its director one of ... , founder of Brown University,s Institute for Brain Science, ...
(Date:7/10/2014)... 2014 Product and process impurities ... abundance and are often “lost in the noise,” ... Join presenters Dr. Rowel Tobias, Senior Scientist, Protein ... Head of Quality at Nanotherapeutics, Inc., to lear ... speed detection and quantitation while achieving the required ...
(Date:7/10/2014)... (PRWEB) July 10, 2014 Robert Harman, DVM, ... Medicine company, is proud to announce the relaunch of his ... with a new series called “ What are Stem Cells ... an honest and straightforward foundation in the basics of stem ... decision on the right type of treatment when considering regenerative ...
(Date:7/10/2014)... July 10, 2014 On July ... Medvedev , presented Russia,s first ... . The Company is developing a unique project called ... BIOCAD develops a number of innovative drugs based on ... The ceremony took place at the International Exhibition "Innoprom ...
Breaking Biology Technology:John P. Donoghue is Taking the Lead at the Wyss Center and is Appointed Professor at EPFL and University of Geneva 2John P. Donoghue is Taking the Lead at the Wyss Center and is Appointed Professor at EPFL and University of Geneva 3Novel Ms Techniques Speed Detection of Biopharmaceutical Product and Process Impurities, New Webinar Hosted by Xtalks 2Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 2Robert Harman, DVM Talks About What Stem Cells are in His Latest Blog Series for Vet-Stem, Inc. 3Dmitry Medvedev Presented BIOCAD the First National "Industry" Award 2
... Novavax, Inc. (Nasdaq: NVAX ) a clinical-stage vaccine company, ... Annual Health Care Conference 2009 on December 2, 2009 at 12:30 ... Novavax will provide an overview of the company,s business strategy, research ... live audio only presentation can be accessed via the Company website ...
... 30 Dr. Jessica Torrente, Assistant Professor of Radiology ... demonstrated the integration and use of Breast-Specific Gamma Imaging ... for the diagnosis of breast cancer today at the ... (RSNA). , "The purpose of the exhibit was to ...
... 30 BioMarin Pharmaceutical Inc. (Nasdaq: BMRN ) ... has granted orphan drug designation for 3,4-diaminopyridine (3,4-DAP), amifampridine ... Syndrome (LEMS). 3,4-DAP has previously received orphan drug ... the Committee for Medicinal Products for Human Use of ...
Cached Biology Technology:NOVAVAX to Present at the Piper Jaffray 21st Annual Health Care Conference 2Breast-Specific Gamma Imaging In Clinical Practice as an Adjunct Imaging Modality for Diagnosis of Breast Cancer 2FDA Grants Orphan Drug Designation for 3,4-DAP for LEMS 2FDA Grants Orphan Drug Designation for 3,4-DAP for LEMS 3FDA Grants Orphan Drug Designation for 3,4-DAP for LEMS 4
... [RS17 ] to PRKAR2 cAMP is ... of cellular functions. cAMP exerts its effects ... which transduces the signal through phosphorylation of ... AMPK is a tetramer composed of two ...
The large Dodeca stainer shaking rack holds the staining trays in the large Dodeca stainer....
...
...
Biology Products: