Navigation Links
American Chemical Society’s Weekly PressPac -- May 7, 2008
Date:5/12/2008

ARTICLE #1 FOR IMMEDIATE RELEASE

Identifying abnormal protein levels in diabetic retinopathy
Journal of Proteome Research

Researchers in Massachusetts are reporting an advance in bridging huge gaps in medical knowledge about the biochemical changes that occur inside the eyes of individuals with diabetic retinopathy (DR) a leading cause of vision loss and blindness in adults. In a study scheduled for the June 6 issue of ACS monthly Journal of Proteome Research, they report discovery of 37 proteins that were increased or decreased in the eyes of patients with DR compared to patients without the disease.

Edward P. Feener and colleagues point out that DR is a complication of diabetes that affects the eyesight of millions of people. It involves damage to blood vessels in the retina, the light sensitive tissue in the back of the eye. Physicians know that vessels grow abnormally, swell, and leak in DR. However, they have little understanding of the biochemical changes underlying those damaging events.

The researchers studied eye fluid from individuals with and without DR who were undergoing eye surgery. They analyzed proteins in the vitreous, the gel-like material inside the eye between the retina and the lens. The study found 252 proteins in the fluid, including 37 proteins that showed changes that were associated with proliferative diabetic retinopathy, the most severe form of the disease. The study could lead to new insights into disease mechanisms and new treatments, the article states. MTS

ARTICLE #1 FOR IMMEDIATE RELEASE Characterization of the Vitreous Proteome in Diabetes without Diabetic Retinopathy and Diabetes with Proliferative Diabetic Retinopathy

DOWNLOAD FULL TEXT ARTICLE http://dx.doi.org/10.1021/pr800112g

CONTACT:
Edward P. Feener, Ph.D.
Joslin Diabetes Center
Boston, Massachusetts 02215
Phone:
'/>"/>

Contact: Michael Woods
m_woods@acs.org
202-872-4400
American Chemical Society
Source:Eurekalert  

0

GOOD

Page: 1 2 3 4 5 6 7 8

Related biology news :

1. American Chemical Societys Weekly PressPac -- April 30, 2008
2. Highlights from the May 2008 Journal of the American Dietetic Association
3. US Patent Office rejects companys claim for bean commonly grown by Latin American farmers
4. UMass Medical Schools Craig Mello elected to American Academy of Arts and Sciences
5. Nobel laureate Dr. Linda Buck elected to American Academy of Arts & Sciences 2008 Class of Fellows
6. UTSA hosts North American Energy Summit May 1-2
7. American Chemical Societys Weekly PressPac -- April 23, 2008
8. Tips from the Journals of the American Society for Microbiology
9. American College of Medical Genetics makes genetic testing recommendations in new policy statement
10. American Chemical Societys Weekly PressPac -- April 16, 2008
11. Three Dimensional Visualization of Right Ventricle Provides Important Information for Treatment of Patients with Tetralogy of Fallot, According to a Study in The American Journal of Cardiology

Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
American Chemical Society’s Weekly PressPac -- May 7, 2008
American Chemical Society’s Weekly PressPac -- May 7, 2008
(Date:12/2/2009)...ELPHIA Mexican-American adolescents exposed to ci...o pick up the habit themselves, and this may be pa...oking initiation, according to new study findings....n the United States and highlights the global impl...ork Convention on Tobacco Control, which includes ...
(Date:12/2/2009)...AYETTE, Ind. ╤ A Smoky Mountain forest,s woo...lay a role in how forest understories recover from... , Despite heavy logging in portions of the fore...um plants on the secondary forest floor was simila... Purdue assistant professor of forestry and natura...
(Date:12/2/2009)...- A team comprised of undergraduate students from ...nors in a national poster contest hosted by the In... (ISPE). , The annual contest highlights the res...month at the ISPE Annual Meeting in San Diego, Cal...a Posterior Criciate Ligament Tensioning Device," ...
Breaking Biology News(10 mins):Watching movies featuring characters who smoke negatively influences Mexican-American teens 2Study finds logging effects vary based on a forest's history, climate 2World Day to Combat Desertification focuses on human security 8869 1World Day to Combat Desertification focuses on human security 8869 2Innovative system for monitoring coastline processes 8867 1Innovative system for monitoring coastline processes 8867 2The Consumers Role in Medication Safety An Interactive Discussion with a Pharmacist on Live TV 49204 1The Consumers Role in Medication Safety An Interactive Discussion with a Pharmacist on Live TV 49204 2
... the January 1 issue of Genes & Development, D...3 inhibitor, Mdm2, as a promising target for cance...itical role in cancer formation, and many anticanc... tumor formation. Mdm2 is a key inhibitor of p53 a...activity in cells. However, conflicting evidence e...
...e risk of serious suicide attempts or death by sui...ts start taking antidepressant medication, accordi...researchers and published in the January issue of ... found that the risk of suicidal behavior after st... than the risk posed by older medications. , Thes...
...searchers have developed a method to engineer bloo...ed heart muscle. Trials have resulted in signific...ublished in the journal Artificial Organs. , Wit...nd contributing to increasing mortality rates, the...s. One of the specific challenges in the field of...
Other Biology News:Suicide risk does not increase when adults start using antidepressants, study finds 2
(Date:12/3/2009)...LVILLE, N.Y., Dec. 3 Nikon Corpora..., announced today that it has signed a licensing a...e rights to use the Stochastic Optical Reconstruct... of the agreement, Nikon will manufacture STORM en...N-STORM name. ,, Nikon Corporation President, ...
(Date:12/3/2009)...LTHAM, Mass., Dec. 3 Inv... global leader in enabling individuals to take cha...rapid diagnostics and health management, has decla...Convertible Perpetual Preferred Stock ( IMA-PB). T...ck in an amount per share equal to the quotient of...
(Date:12/2/2009)..., NEW YORK, Dec. 2 Reportlinker.c...available in its catalogue: ,, Neurostimulatio....reportlinker.com/p0164232/Neurostimulation---A-Gl...rostimulation market stands enthused by the growin... in age-related diseases such as, Parkinson,s, and...
(Date:12/2/2009)...TUSTIN, Calif., Dec. 2 P...day reported completion of patient enrollment in a...174; in patients with relapsed glioblastoma multif...otara is a targeted monoclonal antibody linked to ...treatment for GBM. Cotara specifically targets ce...
Breaking Biology Technology:Nikon Corporation Acquires License From Harvard University For 'STORM' Super Resolution Microscopy -- Will Create Innovative New 'N-STORM' Microscope 2Nikon Corporation Acquires License From Harvard University For 'STORM' Super Resolution Microscopy -- Will Create Innovative New 'N-STORM' Microscope 3Reportlinker Adds Neurostimulation - A Global Market Perspective 2Reportlinker Adds Neurostimulation - A Global Market Perspective 3Reportlinker Adds Neurostimulation - A Global Market Perspective 4Reportlinker Adds Neurostimulation - A Global Market Perspective 5Reportlinker Adds Neurostimulation - A Global Market Perspective 6Peregrine Completes Patient Enrollment in Cotara(R) Dose Confirmation and Dosimetry Brain Cancer Trial 2Peregrine Completes Patient Enrollment in Cotara(R) Dose Confirmation and Dosimetry Brain Cancer Trial 3Peregrine Completes Patient Enrollment in Cotara(R) Dose Confirmation and Dosimetry Brain Cancer Trial 4Peregrine Completes Patient Enrollment in Cotara(R) Dose Confirmation and Dosimetry Brain Cancer Trial 5
...J., Feb. 5 Sopherion Therapeutics, LLC, a biophar...commercialization of anti-cancer therapies, today ...I study of nonpegylated liposomal doxorubicin (Myo... Research . The study was supported by a grant fr...ancer Cooperative Group (SOLTI). , , The study re...
...ins one of the most serious diseases worldwide, cl...er year in tropical and sub-tropical regions, the ...age. Efforts to eliminate this mosquito-borne ill...e are growing concerns about resistance to insecti...me Research ( www.genome.org ), researchers have ...
..., Feb. 4 Illinois, a state that hosted,the first ...ecades ago, made,history again this week with the ...of higher yielding soybean technology. The techno... trait, is expected to be the platform for,Monsant... , (Photo: http://www.newscom.com/cgi-bin/pr...
Other Biology Technology:Sopherion Therapeutics, LLC Announces Publication of Phase I/II Myocet(R) (Nonpegylated Liposomal Doxorubicin) Data in Advanced Breast Cancer Patients 2Sopherion Therapeutics, LLC Announces Publication of Phase I/II Myocet(R) (Nonpegylated Liposomal Doxorubicin) Data in Advanced Breast Cancer Patients 3Sopherion Therapeutics, LLC Announces Publication of Phase I/II Myocet(R) (Nonpegylated Liposomal Doxorubicin) Data in Advanced Breast Cancer Patients 4Mosquito genes linked to insecticide resistance may be new target in fight against malaria 2Historic Seed Delivery Made in Illinois for First New Soybean Varieties With the Greater Yield Potential of Roundup Ready 2 Yield(TM) 2Historic Seed Delivery Made in Illinois for First New Soybean Varieties With the Greater Yield Potential of Roundup Ready 2 Yield(TM) 3
...rrers operate without any moving parts such as mot...G Magnetic Stirrers 100% wear-free and maintenance...an be hermetically sealed, making it inaccessible ...OMAG Magnetic Stirrers are particularly suitable f...
...nation, which prevents false positive results ,Des...plifications without degrading native nucleic acid...d for use with GeneAmp PCR core reagents and GeneA...r Prevention Kit provides reagents for a simple ye...
...safe KS convince with an optimum product, personne... frameless slanted window does not obscure the vie...kes it easy to work in a relaxed posture. The larg...ensures ease of handling. ,The eye-level display ...
Fluoroskan Ascent FL, 100-240 V from Thermo Scientific
Biology Products: