Navigation Links
American Academy of Microbiology releases resistance report

What do cancer cells, weeds, and pathogens have in common? They all evolve resistance to the treatments that are supposed to eliminate them. However, researchers developing the next generation of antibiotics, herbicides, and anti-cancer therapeutics rarely come together to explore the common evolutionary principles at work across their different biological systems. The new American Academy of Microbiology report "Moving Targets: Fighting Resistance in Infections, Pests, and Cancer" concludes that scientists working on different kinds of treatments have much to learn from each other. Applying lessons learned about the evolution of resistance in different biological systems during the earliest stages of drug and pesticide design could lead to more effective treatments for patients, farmers, and public health organizations.

Do you think the oncologists at a cutting-edge research hospital ever sit down with local farmers? Do you think the pharmaceutical researchers developing the next generation of anti-HIV drugs spend any time with the plant scientists working on the next generation of Roundup Ready soybeans? If your answer to both questions is no, you would be mostly right. Even though all of these people are dealing with exactly the same evolutionary phenomena, they do not recognize themselves as a single scientific community and rarely get a chance to learn from each other. What they all have in common is that they are trying to eliminate an unwanted living entity but the treatments they develop eventually lose effectiveness because the target evolves resistance.

The emergence of resistance is a phenomenon with ancient evolutionary roots, although the human role in triggering resistance was little appreciated before the advent of widespread antibiotic and pesticide use in the 1950s. In Silent Spring, the prescient Rachel Carson wrote in 1962 that "by their very nature chemical controls are self-defeating, for they have been devised and applied without taking into account the complex biological systems against which they have been blindly hurled." Sadly, in the fifty years since Silent Spring was published, biologists, doctors, and farmers continue to be plagued with resistance evolution by the species they seek to control. This phenomenon is witnessed in medicine in the emergence of antibiotic resistance and when tumors become intractable to standard anti-cancer medications, in agriculture when insecticides and herbicides lose effectiveness, and in public health when disease-carrying insects develop resistance to control strategies. The report "Moving Targets: Fighting Resistance in Infections, Pests, and Cancer" makes clear that a multi-disciplinary approach to the phenomenon of resistance can be very powerful.


Contact: Garth Hogan
American Society for Microbiology

Related biology news :

1. American College of Rheumatology releases first classification criteria for polymyalagia rheumatica
2. Common North American frog identified as carrier of deadly amphibian disease
3. UC research tests new tool to guide reintroduction of the American chestnut
4. American Society of Plant Biologists honors early career women scientists
5. Scripps Research Institute Professor Gerald F. Joyce elected to American Academy of Arts & Sciences
6. Professor known for work with hunter-gatherers elected to American Academy of Arts and Sciences
7. Elsevier selected as new publisher of the American Journal of Geriatric Psychiatry
8. New study published on fertility awareness among American university students
9. The American Society for Microbiology honors Ellen Jo Baron
10. Steve Fisher joins American Health IT LLC as VP of Operations
11. University of Tennessee anthropologists find American heads are getting larger
Post Your Comments:
(Date:11/9/2015)... JOSE, Calif. , Nov. 9, 2015  Synaptics ... human interface solutions, today announced broader entry into the ... vehicle-specific solutions that match the pace of consumer electronics ... and biometric sensors are ideal for the automotive industry ... vehicle. Europe , ...
(Date:10/29/2015)... 2015   MedNet Solutions , an innovative SaaS-based ... clinical research, is pleased to announce that it has ... as one of only three finalists for a ... and Growing" category. The Tekne Awards honor Minnesota ... technology innovation and leadership. iMedNet™ eClinical ...
(Date:10/29/2015)... ARBOR, Mich. , Oct. 29, 2015 /PRNewswire/ ... Eurofins Genomics for U.S. distribution of its DNA ... DNA-seq kit and Rubicon,s new ThruPLEX Plasma-seq kit. ... to enable the preparation of NGS libraries for ... plasma for diagnostic and prognostic applications in cancer ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... 2015 --> ... - 2020 report analyzes that automating biobanking workflow ... in long-term samples, minimizing manual errors, improving the ... manual errors such as mislabeling or inaccurate sample ... plays a vital role in blood fractionation, DNA ...
(Date:11/25/2015)... BRUSSELS , November 25, 2015 ... in cat and human plaque and pave the way for ... health problems in cats     ... the most commonly diagnosed health problems in cats, yet relatively ... until now. Two collaborative studies have been conducted by researchers ...
(Date:11/25/2015)... 2015 /PRNewswire/ - Aeterna Zentaris Inc. (NASDAQ:  AEZS; TSX: ... prospects remain fundamentally strong and highlights the following ... received DSMB recommendation to continue the ZoptEC Phase ... the final interim efficacy and safety data ... men with heavily pretreated castration- and Taxane-resistant prostate ...
(Date:11/25/2015)... , November 25, 2015 ... Report is a professional and in-depth study on ...      (Logo: ) , ... the industry including definitions, classifications, applications and industry ... for the international markets including development trends, competitive ...
Breaking Biology Technology: