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Amarna Therapeutics B.V. and TNO announce SVac research and development partnership
Date:6/9/2009

logies and is yet another important step in our establishment of a fully integrated and highly innovative package of biopharmaceutical development capabilities” says Menzo Havenga, Managing Director of Biosciences at TNO.


About Amarna Therapeutics
Amarna Therapeutics B.V. is a Biotechnology company that develops therapeutic vaccinations to treat immunity-associated diseases including autoimmune diseases, allergies and cancer and gene therapies to treat genetic disorders. The base of Amarna’s therapeutics is the SVac viral gene delivery vector platform, which provides sensational characters unheard of in the Pharma arena, creating opportunities to serve markets with enormous potential due to clinical unmet needs.

About SVac
Our SVac viral gene delivery vector platform has a number of unique properties compared to other viral gene delivery vectors such as lentiviral, poxviral, alphaviral, adenoviral and adeno-associated virus (AAV) vector systems. SVac is non-immunogenic in humans, highly stable, safe to use and can be cost effectively produced in large amounts in a proprietary producer cell line denoted SuperVero. Moreover, the vector has extensively been tested for safety in model animals. The SuperVero cell line has been qualified and tested using Quality Control (QC) assays and its use for manufacturing clinical trial material has been validated. The whole vector production process is similar to the current manufacturing processes of the polio, rabies and influenza virus vaccines in which a master seed virus is seeded to producer cells in large fermentors. Because of its immunological inertia in man SVac is the only vector system known that is suitable for for treating genetic disorders and immunity associated diseases.

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