Navigation Links
Alzheimer's disease research attracts first partner

The Australian Alzheimer's disease cluster study The Australian Imaging, Biomarker and Lifestyle Flagship Study of Ageing (AIBL) has secured its first collaborative research agreement with a major strategic alliance partner, Pfizer Australia.

AIBL is the world's largest study of its type, and aims to better understand the causes of Alzheimer's disease and to discover a method for early diagnosis.

The study is an initiative of the CSIRO Preventative Health Flagship which involves collaborative, multi-organisational research across Australia and brings together world leaders in the fundamental science of Alzheimer's disease.

Since its inception in 2006, AIBL has recruited a cohort of over 1000 volunteers over the age of 60 and investigated four major disease indications: neuro-imaging, clinical and cognitive testing, blood biomarker samples, and health and lifestyle data.

The leader of the AIBL study, Professor David Ames from the University of Melbourne, says the partnership with Pfizer Australia will see a panel of biomarkers tested against the AIBL cohort. "If we are able to identify blood-based biomarkers it will enable us to identify which people will develop Alzheimer's disease before any symptoms are present," he says.

"Early pre-symptomatic diagnosis is an essential development which will allow us to test new disease modifying therapies with the aim of delaying the onset of Alzheimer's disease in susceptible individuals."

According to Pfizer Australia's Head of Strategic Alliances, Dr Daniel Grant, the three-year deal, valued at more than $A1.1m, again demonstrates the value Pfizer Australia sees in collaborating with Australian scientists and clinicians.

"The collaboration with the AIBL study also highlights the importance that we place upon the discovery and use of biomarkers as we seek to develop innovative medicines to treat neurodegenerative diseases such as Alzheimer's disease," he says.

Professor Ames says the study has already had success with neuro-imaging results showing that the diagnosis of Alzheimer's disease can be brought forward by up to 18 months using a technique called PiB PET scans.

"This work places Australia at the forefront of neuro-imaging in Alzheimer's disease, but unfortunately, because of the large cost per scan it is unlikely at this stage to be useful for large population screening.

"Ultimately, we are working towards the 'holy grail' of Alzheimer's research, which is to find a simple blood test something which we hope this partnership will facilitate."

The Director of CSIRO's Preventative Health National Research Flagship, Dr Richard Head, says the progress made to date highlights the value of a national collaborative team working together on one of Australia's biggest community health challenges.

The AIBL Study of Ageing is a collaboration initiated by the CSIRO Preventative Health National Research Flagship involving; The University of Melbourne, Edith Cowan University - Western Australia, Neurosciences Australia, Mental Health Research Institute of Victoria and National Ageing Research Institute and the Preventative Health Flagship.The Australian eHealth Research Centre is also involved in developing image analysis methods designed to quantify the disease's progression .

National Research Flagships

CSIRO initiated the National Research Flagships to provide science-based solutions in response to Australia's major research challenges and opportunities. The nine Flagships form multidisciplinary teams with industry and the research community to deliver impact and benefits for Australia.


Contact: Michelle Zucker
CSIRO Australia

Related biology news :

1. Paradigm shift in Alzheimerss research: new treatments
2. Antioxidant overload may underlie a heritable human disease
3. Gender, coupled with diabetes, affects vascular disease development
4. Study links cat disease to flame retardants in furniture and to pet food
5. Humans fostering forest-destroying disease
6. Emerging (disease) markets
7. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
8. Clemson chemists discover new way antioxidants fight debilitating diseases
9. Finding that 1-in-a-billion that could lead to disease
10. Study shows link between alcohol consumption and hiv disease progression
11. Natural chemical found in broccoli helps combat skin blistering disease
Post Your Comments:
(Date:11/17/2015)... Mass. , Nov. 17, 2015 Pressure ... leader in the development and sale of broadly enabling, ... worldwide life sciences industry, today announced it has received ... its $5 million Private Placement (the "Offering"), increasing the ... $4,025,000.  One or more additional closings are expected in ...
(Date:11/12/2015)... golden retriever that stayed healthy despite having the gene ... new lead for treating this muscle-wasting disorder, report scientists ... and Harvard and the University of São Paolo in ... pinpoints a protective gene that boosts muscle regeneration, ... Children,s lab of Lou Kunkel , PhD, is ...
(Date:11/12/2015)... 11, 2015   Growing need for low-cost, ... has been paving the way for use of ... discrete analytes in clinical, agricultural, environmental, food and ... used in medical applications, however, their adoption is ... to continuous emphasis on improving product quality and ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... , Nov. 25, 2015  Neurocrine Biosciences, Inc. (Nasdaq: ... , President and CEO of Neurocrine Biosciences, will be ... in New York . ... the website approximately 5 minutes prior to the presentation ... of the presentation will be available on the website ...
(Date:11/25/2015)... , ... November 25, 2015 , ... ... the Organization of Black Aerospace Professionals (OPBAP) has been formalized with the signing ... AMA team leaders met with OPBAP leaders Capt. Karl Minter and Capt. Albert ...
(Date:11/25/2015)... Oregon , November 25, 2015 ... Market Research Report is a professional and in-depth ... industry.      (Logo: ) ... overview of the industry including definitions, classifications, applications ... is provided for the international markets including development ...
(Date:11/24/2015)... Nov. 24, 2015  Asia-Pacific (APAC) holds the ... (CRO) market. The trend of outsourcing to low-cost ... but higher volume share for the region in ... however, margins in the CRO industry will improve. ... ( ), finds that the market ...
Breaking Biology Technology: