Navigation Links
Alzheimer's disease research attracts first partner
Date:10/16/2008

The Australian Alzheimer's disease cluster study The Australian Imaging, Biomarker and Lifestyle Flagship Study of Ageing (AIBL) has secured its first collaborative research agreement with a major strategic alliance partner, Pfizer Australia.

AIBL is the world's largest study of its type, and aims to better understand the causes of Alzheimer's disease and to discover a method for early diagnosis.

The study is an initiative of the CSIRO Preventative Health Flagship which involves collaborative, multi-organisational research across Australia and brings together world leaders in the fundamental science of Alzheimer's disease.

Since its inception in 2006, AIBL has recruited a cohort of over 1000 volunteers over the age of 60 and investigated four major disease indications: neuro-imaging, clinical and cognitive testing, blood biomarker samples, and health and lifestyle data.

The leader of the AIBL study, Professor David Ames from the University of Melbourne, says the partnership with Pfizer Australia will see a panel of biomarkers tested against the AIBL cohort. "If we are able to identify blood-based biomarkers it will enable us to identify which people will develop Alzheimer's disease before any symptoms are present," he says.

"Early pre-symptomatic diagnosis is an essential development which will allow us to test new disease modifying therapies with the aim of delaying the onset of Alzheimer's disease in susceptible individuals."

According to Pfizer Australia's Head of Strategic Alliances, Dr Daniel Grant, the three-year deal, valued at more than $A1.1m, again demonstrates the value Pfizer Australia sees in collaborating with Australian scientists and clinicians.

"The collaboration with the AIBL study also highlights the importance that we place upon the discovery and use of biomarkers as we seek to develop innovative medicines to treat neurodegenerative diseases such as Alzheimer's disease," he says.

Professor Ames says the study has already had success with neuro-imaging results showing that the diagnosis of Alzheimer's disease can be brought forward by up to 18 months using a technique called PiB PET scans.

"This work places Australia at the forefront of neuro-imaging in Alzheimer's disease, but unfortunately, because of the large cost per scan it is unlikely at this stage to be useful for large population screening.

"Ultimately, we are working towards the 'holy grail' of Alzheimer's research, which is to find a simple blood test something which we hope this partnership will facilitate."

The Director of CSIRO's Preventative Health National Research Flagship, Dr Richard Head, says the progress made to date highlights the value of a national collaborative team working together on one of Australia's biggest community health challenges.

The AIBL Study of Ageing is a collaboration initiated by the CSIRO Preventative Health National Research Flagship involving; The University of Melbourne, Edith Cowan University - Western Australia, Neurosciences Australia, Mental Health Research Institute of Victoria and National Ageing Research Institute and the Preventative Health Flagship.The Australian eHealth Research Centre is also involved in developing image analysis methods designed to quantify the disease's progression .

National Research Flagships

CSIRO initiated the National Research Flagships to provide science-based solutions in response to Australia's major research challenges and opportunities. The nine Flagships form multidisciplinary teams with industry and the research community to deliver impact and benefits for Australia.


'/>"/>

Contact: Michelle Zucker
Michelle.Zucker@csiro.au
61-883-038-808
CSIRO Australia
Source:Eurekalert

Related biology news :

1. Paradigm shift in Alzheimerss research: new treatments
2. Antioxidant overload may underlie a heritable human disease
3. Gender, coupled with diabetes, affects vascular disease development
4. Study links cat disease to flame retardants in furniture and to pet food
5. Humans fostering forest-destroying disease
6. Emerging (disease) markets
7. University of Pennsylvania researchers develop formula to gauge risk of disease clusters
8. Clemson chemists discover new way antioxidants fight debilitating diseases
9. Finding that 1-in-a-billion that could lead to disease
10. Study shows link between alcohol consumption and hiv disease progression
11. Natural chemical found in broccoli helps combat skin blistering disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2016)... LONDON , June 2, 2016 ... Systems, Manned Platforms, Unmanned Systems, Physical Infrastructure, Support & ... intelligence provider visiongain offers comprehensive analysis of ... that this market will generate revenues of $17.98 billion ... Systems acquired DVTEL Inc, a leader in software and ...
(Date:5/16/2016)... --  EyeLock LLC , a market leader of iris-based ... IoT Center of Excellence in Austin, Texas ... embedded iris biometric applications. EyeLock,s iris authentication ... with unmatched biometric accuracy, making it the most proven ... platform uses video technology to deliver a fast and ...
(Date:4/28/2016)... BANGALORE, India , April 28, 2016 ... subsidiary of Infosys (NYSE: INFY ), and Samsung ... global partnership that will provide end customers with a ... and payment services.      (Logo: http://photos.prnewswire.com/prnh/20130122/589162 ... for financial services, but it also plays a fundamental part ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... , June 27, 2016  Global demand ... 4.6 percent through 2020 to $7.2 billion.  This ... and beverages, cleaning products, biofuel production, animal feed, ... biotechnology, diagnostics, and biocatalysts). Food and beverages will ... driven by increasing consumption of products containing enzymes ...
(Date:6/27/2016)... ... June 27, 2016 , ... Cancer experts from ... believe could be a new and helpful biomarker for malignant pleural mesothelioma. Surviving ... to read it now. , Biomarkers are components in the blood, tissue ...
(Date:6/27/2016)... ... 27, 2016 , ... Rolf K. Hoffmann, former senior vice ... University of North Carolina Kenan-Flagler Business School effective June 27. , ... with a focus on the school’s international efforts, leading classes and participating in ...
(Date:6/24/2016)... TOKYO , June 24, 2016  Regular discussions on ... to take place between the two entities said Poloz. ... in Ottawa , he pointed to the ... and the federal government. ... Poloz said, "Both institutions have common economic goals, why not ...
Breaking Biology Technology: