Navigation Links
Alligator stem cell study gives clues to tooth regeneration
Date:5/14/2013

he dental laminain different developmental stages. The tooth units are structured to enable a smooth transition from dislodgement of the functional, mature tooth to replacement with the new tooth. Identifying three developmental phases for each tooth unit, the researchers conclude that the alligator dental laminae contain what appear to be stem cells from which new replacement teeth develop.

"Stem cells divide more slowly than other cells," said co-author Randall B. Widelitz, Ph.D., associate professor of pathology at the Keck School of Medicine. "The cells in the alligator's dental lamina behaved like we would expect stem cells to behave. In the future, we hope to isolate those cells from the dental lamina to see whether we can use them to regenerate teeth in the lab."

The researchers also intend to learn what molecular networks are involved in repetitive renewal and hope to apply the principles to regenerative medicine in the future.

The authors also report novel cellular mechanisms by which the tooth unit develops in the embryo and molecular signaling that speeds growth of replacement teeth when functional teeth are lost prematurely. Co-authors include colleagues from the Louisiana Department of Wildlife and Fisheries, University of Georgia, National Cheng Kung University, National Taiwan University, and Xiangya Hospital in China. The research was supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases through grants 5R01AR042177-19, 5R01AR060306-03 and 2R01AR047364-11A1.


'/>"/>

Contact: Alison Trinidad
alison.trinidad@usc.edu
323-442-3941
University of Southern California - Health Sciences
Source:Eurekalert

Page: 1 2

Related biology news :

1. Despite their thick skins, alligators and crocodiles are surprisingly touchy
2. Study by UC Santa Barbara researchers suggests that bacteria communicate by touch
3. Law that regulates shark fishery is too liberal: UBC study
4. New study will help protect vulnerable birds from impacts of climate change
5. Study jointly led by UCSB researcher supports theory of extraterrestrial impact
6. BYU study: Using a gun in bear encounters doesnt make you safer
7. 15-year study: When it comes to creating wetlands, Mother Nature is in charge
8. Pycnogenol (French maritime pine bark extract) shown to improve menopause symptoms in new study
9. Crystal structure of archael chromatin clarified in new study
10. EU-funded study underlines importance of Congo Basin for global climate and biodiversity
11. University of Houston study shows BP oil spill hurt marshes, but recovery possible
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/23/2014)... Pattern formation is essential in the development of animals ... how can genetic information be translated in a reliable ... , The French-flag model of stripe formation is ... by the different colours of the French flag, is ... i.e. at high, middle or low concentrations of the ...
(Date:9/23/2014)... 23 de septiembre de 2014 ... 1290 Infinity II LC, el nuevo instrumento ... su portafolio de cromatografía líquida. El sistema ... de laboratorio que alcancen nuevos niveles de ... uso y capacidad de integración de laboratorio. ...
(Date:9/22/2014)... Researchers at the University of Chicago have shown that ... (ICU) only a handful of pathogenic microbe species remain ... pathogens and discovered that some can become deadly when ... to illness. , The findings, published in mBio ... for Microbiology, may lead to better monitoring and treatment ...
Breaking Biology News(10 mins):Recreating the stripe patterns found in animals by engineering synthetic gene networks 2Agilent Technologies anuncia el lanzamiento del Sistema 1290 Infinity II LC 2Agilent Technologies anuncia el lanzamiento del Sistema 1290 Infinity II LC 3Critically ill ICU patients lose almost all of their gut microbesand the ones left aren't good 2Critically ill ICU patients lose almost all of their gut microbesand the ones left aren't good 3
... best-studied single-celled organisms around, is a master of industrial efficiency. ... just one product: itself. It exists to make copies of ... the lowest possible cost, with the greatest possible efficiency. ... by the energy and resources it uses to maintain its ...
... facial structure of an ancient relative of modern humans ... hard nuts and seeds as part of a survival ... team of researchers that includes Florida State University,s Dennis ... Proceedings of the National Academy of Science, ...
... gearing up to return to Russia to oversee preparations for ... launch on 16 March 2009. This follows implementation of the ... delayed the launch of GOCE by Eurockot Launch Services last ... at the Plesetsk Cosmodrome in northern Russia to arrange logistical ...
Cached Biology News:Bacteria are models of efficiency 2March launch planned for ESA's gravity mission 2
(Date:9/22/2014)... 22, 2014 Patients who were treated with a statin ... were significantly more likely to survive than those who ... JAMA Neurology . This study was conducted by ... of cholesterol-lowering statins can improve survival in victims of ... or obstruction of a blood vessel that blocks blood ...
(Date:9/22/2014)... researchers at the USC Viterbi School of Engineering, ... microfluidic system quickly and cheaply by simply snapping ... systems are used in many fields including engineering, ... of fluids for use in applications such as ... testing, and synthetic chemistry. Traditionally, microfluidic devices are ...
(Date:9/22/2014)... Minnesota electrical engineering researchers have developed a unique ... mechanical transportation of light. The discovery could have ... optical devices for computation and communication. , The ... computer engineering assistant professor Mo Li and his ... and will appear in the October issue of ...
(Date:9/22/2014)... 22, 2014 US demand to rise 3.9% ... biocides is forecast to rise 3.9 percent per year ... is projected to increase 1.3 percent per year to ... rebound in construction expenditures will support demand for biocides ... while growth in consumer spending and manufacturing output will ...
Breaking Biology Technology:Statin use during hospitalization for hemorrhagic stroke associated with improved survival 2Lego-like modular components make building 3-D 'labs-on-a-chip' a snap 2Lego-like modular components make building 3-D 'labs-on-a-chip' a snap 3Lego-like modular components make building 3-D 'labs-on-a-chip' a snap 4Lego-like modular components make building 3-D 'labs-on-a-chip' a snap 5Engineers show light can play seesaw at the nanoscale 2US Biocides Market 2US Biocides Market 3
... and Webcast on November 9 at 8:00 a.m. ... Halozyme Therapeutics, Inc.,(Nasdaq: HALO ), a biopharmaceutical ... matrix, today reported financial,results for the three and ... unique capabilities in navigating the complexities of the,extracellular ...
... Kosan Biosciences,Incorporated (Nasdaq: KOSN ) today reported financial ... Net loss for the quarter and nine months ended ... per share and $0.46 per share,compared to a net loss ... share, in the same periods last year. Revenues were ...
... 8 Inverness Medical,Innovations, Inc. (Amex: IMA ), ... market and other conditions, 7,000,000 shares of its common,stock ... public offering. Certain selling stockholders of the Company,are also ... stock in the,offering. The Company expects to grant the ...
Cached Biology Technology:Halozyme Therapeutics Reports 2007 Third Quarter Financial Results 2Halozyme Therapeutics Reports 2007 Third Quarter Financial Results 3Halozyme Therapeutics Reports 2007 Third Quarter Financial Results 4Halozyme Therapeutics Reports 2007 Third Quarter Financial Results 5Halozyme Therapeutics Reports 2007 Third Quarter Financial Results 6Kosan Announces Third Quarter 2007 Financial Results 2Kosan Announces Third Quarter 2007 Financial Results 3Kosan Announces Third Quarter 2007 Financial Results 4Kosan Announces Third Quarter 2007 Financial Results 5Kosan Announces Third Quarter 2007 Financial Results 6Kosan Announces Third Quarter 2007 Financial Results 7Inverness Medical Innovations Announces Proposed Public Offering of Common Stock 2Inverness Medical Innovations Announces Proposed Public Offering of Common Stock 3
Anti-gp120/160(SIV/mac239) Immunogen: gp120(SIV/mac239) protein (Genebank accession #M33262)...
Annexin V Binding Buffer, 10X Concentrate Buffer , 50 ml Consult technical datasheet for details....
IHC Select Anti-p53, prediluted,wild & mutant, a.a. 19-26, clone DO-7 Immunogen: Human p53 Available Date: 37775...
Feline Rhinotracheitis Virus...
Biology Products: