Navigation Links
Allergy vaccine is nothing to sneeze at
Date:3/21/2011

Monash University researchers are working on a vaccine that could completely cure asthma brought on by house dust mite allergies.

If successful, the vaccine would have the potential to cure sufferers in two to three doses.

Allergies to house dust mites is a leading cause of asthma and the respiratory condition affects more than 2 million Australians and costs more than $600 million in health expenditure each year.

Currently, people allergic to house dust mites must continually clean their environments to remove the microscopic creatures from soft furnishings to avoid an allergic attack. Medications can bring relief for some sufferers, but must be taken regularly. Others respond less well to medications.

Professor El Meeusen, who is working with Professor Robyn O'Hehir, both from the Faculty of Medicine, Nursing and Health Services, believes that a vaccine for people with house dust mite allergies will have a range of health and financial benefits for patients and the government.

"We are aiming to develop a vaccine that can be completely delivered in two to three doses. That means a person suffering from a house dust mite allergy will be able to breathe easily from their final dose," Professor Meeusen said.

"Allergies cost the Australian economy approximately seven billion dollars every year. The potential reduction in cost to the patient and to the government by eradicating a common allergy such as this is immense."

Professor O'Hehir has also made significant gains in developing a vaccine for people with peanut allergies. Currently there is no specific treatment for peanut allergy with avoidance and emergency treatment of anaphylaxis with adrenaline as the only options. Allergen immunotherapy is available for selected patients with house dust mite allergy but typically injections need to be given regularly for three to five years.

"This method of immunisation is quite precarious, because modern medicine still isn't entirely sure how it really works," Professor Meeusen said.

"The immunisation is administered in small doses. Too much can cause anaphylactic shock. It's a very fine line."

Laboratory testing has shown that a genetic predisposition exists to be allergic to more than one allergen.

"We have already found that being allergic to peanuts also represents the likelihood of developing an allergy to house dust mites," Dr Meeusen said.

"In humans it is difficult to look at how the very early stages of allergy occur, because you don't get to see the patient until it is well developed in their allergic response. Our testing enables us to look at the very first time that our models are exposed to the allergen."

From there, the scientists can see which models are going to develop an allergy and which are not, to determine the difference between them.

This research involves using the scientist's knowledge of normal vaccines for infectious diseases to better understand how allergy vaccines work in order to develop more effective and safer products.


'/>"/>

Contact: Karen Sutherland
media@monash.edu
039-903-4840
Monash University
Source:Eurekalert

Related biology news :

1. Pregnant women who eat peanuts may put infants at increased risk for peanut allergy
2. Comprehensive overview of Childrens Interstitial Lung Disease (chILD) in special issue of Pediatric Allergy, Immunology, and Pulmonology
3. Gene site found for childrens food allergy
4. Common allergy drug reduces obesity and diabetes in mice
5. EPA grant to University of Chicago for research on food allergy triggers
6. Nutricia launches Nutra Neocate, weaning product designed for cows’ milk protein allergy
7. Yale team identifies key to potential new treatment for allergy-induced asthma
8. Allergy season: Cigarettes to the rescue?
9. Malfunction of the respiratory epithelium is a cause of allergy?
10. New discovery may lead to new class of allergy drugs
11. REGiMMUNE receives $12 million in grants to develop transplant and allergy drugs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/3/2017)... 3, 2017  Data captured by IsoCode, ... detected a statistically significant association between the ... treatment and objective response of cancer patients ... predict whether cancer patients will respond to ... well as to improve both pre-infusion potency testing ...
(Date:3/28/2017)... The report "Video Surveillance Market ... Storage Devices), Software (Video Analytics, VMS), and Service (VSaaS, ... to 2022", published by MarketsandMarkets, the market was valued ... to reach USD 75.64 Billion by 2022, at a ... year considered for the study is 2016 and the ...
(Date:3/23/2017)... 2017 Research and Markets has announced the ... Trends - Industry Forecast to 2025" report to their offering. ... The Global ... of around 8.8% over the next decade to reach approximately $14.21 ... market estimates and forecasts for all the given segments on global ...
Breaking Biology News(10 mins):
(Date:7/17/2017)... Iowa (PRWEB) , ... July 17, 2017 , ... ... component of its long-standing innovation strategy. A website (openinnovation.pioneer.com) dedicated to ... five strategic areas – trait discovery, plant breeding, enabling technologies, biologicals and digital ...
(Date:7/14/2017)... ... 14, 2017 , ... Sonic Manufacturing Technologies is proud to ... a solar system on its roof top. “We will be independent of the ... Raab stated. The company’s proud history of social responsibility and participation in the ...
(Date:7/13/2017)... IN (PRWEB) , ... July 13, 2017 , ... Thousands ... July and August for the National Aeromodeling Championships (Nats). Pilots come to Muncie to ... try to earn spots on US teams that participate in world championships. , RC ...
(Date:7/13/2017)... ... July 13, 2017 , ... Frederick’s first and ... robust growth in the past year after an intensive restructuring. Under the leadership ... Programs and expanded its board of directors to revitalize the organization. As a ...
Breaking Biology Technology: