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Alcohol helps the brain remember, says new study
Date:4/12/2011

ngthens those synapses that are active when dopamine is released."

Alcohol, in this model, is the enabler. It hijacks the dopaminergic system, and it tells our brain that what we're doing at that moment is rewarding (and thus worth repeating).

Among the things we learn is that drinking alcohol is rewarding. We also learn that going to the bar, chatting with friends, eating certain foods and listening to certain kinds of music are rewarding. The more often we do these things while drinking, and the more dopamine that gets released, the more "potentiated" the various synapses become and the more we crave the set of experiences and associations that orbit around the alcohol use.

Morikawa's long-term hope is that by understanding the neurobiological underpinnings of addiction better, he can develop anti-addiction drugs that would weaken, rather than strengthen, the key synapses. And if he can do that, he would be able to erase the subconscious memory of addiction.

"We're talking about de-wiring things," says Morikawa. "It's kind of scary because it has the potential to be a mind controlling substance. Our goal, though, is to reverse the mind controlling aspects of addictive drugs."


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Contact: Daniel Oppenheimer
oppenheimer@mail.utexas.edu
512-232-0682
University of Texas at Austin
Source:Eurekalert

Page: 1 2

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