Navigation Links
Alan Ashworth to receive award for his breakthrough work in breast cancer

Molecular biologist Alan Ashworth, Ph.D., FRS, the director of the Breakthrough Breast Cancer Research Centre at the Institute of Cancer Research in London will receive the David T. Workman Memorial Award on May 17. The two-year grant of $50,000 from the Samuel Waxman Cancer Research Foundation will support Dr. Ashworth's work with PARP inhibitors in BRCA-mutated cancers.

"I'm both surprised and delighted that the Waxman Foundation has thought to honor me in this way," said Dr. Ashworth. "Recognition from your peers is incredibly important and I'm thrilled."

Dr. Ashworth helped discover the BRCA2 breast cancer gene in 1995. After realizing that BRCA-related cancers had a flawed DNA repair pathway, Dr. Ashworth and his team worked with a biotechnology company to study the use of PARP inhibitors to treat these cancers. They learned that BRCA-defective cancer cells were 1,000 times more sensitive to PARP inhibitors than cells that were normal. His lab is studying the use of PARP inhibitors to treat cancers such as endometrial cancer, ovarian cancer and breast cancer, including triple-negative breast cancer, which responds poorly to normal chemotherapy.

Speaking about Dr. Ashworth's research in triple-negative breast cancer, Samuel Waxman, M.D., the Scientific Director of the Waxman Foundation said it represents a contribution from a scientist unraveling a genomic defect in breast cancer that has resulted in a novel treatment for women who would otherwise have a poor prognosis.

Michael Nierenberg, the Chair of the Foundation added, "The Waxman Foundation is committed to bridging the gap between lab science and the patient. We are excited to help further the important work of Dr. Ashworth and his lab."

Recent recipients of the Workman Award include Stephen Baylin, M.D., and Peter Jones, Ph.D., in 2008 for the development of demethylating agents and epigenetic therapy for hematologic malignancies and Douglas Lowy, M.D., and John Schiller, Ph.D., in 2006 for their advance in preventing cervical cancer with the HPV vaccine.


Contact: Jenny Song
Samuel Waxman Cancer Research Foundation

Related biology news :

1. Rutgers Genetics receives $7.8 million for autism research
2. Herr receives Heinz Award for Technology, the Economy and Employment
3. UCI receives $5M from Edwards Lifesciences
4. Yu receives research funding from the Wallace H. Coulter Foundation
5. UGA Odum School of Ecology professor receives grant to study West Nile Virus in NYC
6. UC Riverside biologist receives prestigious MacArthur Fellowship
7. UC Irvine receives $2.18M to explore nano advancements in DNA sequencing
8. Penn biochemist receives NIH New Innovators Award
9. NYUs Center for Genomics & Systems Biology receives $4.4 million NSF grant
10. K-State chemistry professor to receive Masao Horiba award
11. Einstein researcher receives NIH grant to explore epigenetic regulation of the human genome
Post Your Comments:
(Date:5/16/2016)...   EyeLock LLC , a market leader of ... an IoT Center of Excellence in Austin, ... of embedded iris biometric applications. EyeLock,s iris ... security with unmatched biometric accuracy, making it the most ... EyeLock,s platform uses video technology to deliver a fast ...
(Date:4/28/2016)... and BANGALORE, India , April ... EdgeVerve Systems, a product subsidiary of Infosys (NYSE: ... today announced a global partnership that will provide ... to use mobile banking and payment services.      ... a key innovation area for financial services, but it also ...
(Date:4/19/2016)... , UAE, April 20, 2016 ... be implemented as a compact web-based "all-in-one" system solution ... the biometric fingerprint reader or the door interface with ... of modern access control systems. The minimal dimensions of ... ID readers into the building installations offer considerable freedom ...
Breaking Biology News(10 mins):
(Date:6/27/2016)...   Ginkgo Bioworks , a leading organism ... today awarded as one of the World Economic ... most innovative companies. Ginkgo Bioworks is engineering biology ... world in the nutrition, health and consumer goods ... customers including Fortune 500 companies to design microbes ...
(Date:6/24/2016)... DIEGO , June 24, 2016 ... more sensitively detects cancers susceptible to PARP inhibitors ... circulating tumor cells (CTCs). The new test has ... HRD-targeted therapeutics in multiple cancer types. ... targeting DNA damage response pathways, including PARP, ATM, ...
(Date:6/24/2016)... ... June 24, 2016 , ... Researchers at the Universita Politecnica delle Marche in ... peritoneal or pleural mesothelioma. Their findings are the subject of a new article on ... biomarkers are signposts in the blood, lung fluid or tissue of mesothelioma patients that ...
(Date:6/23/2016)... ... June 23, 2016 , ... UAS LifeSciences, one of ... their brand, UP4™ Probiotics, into Target stores nationwide. The company, which has been ... Target to its list of well-respected retailers. This list includes such fine stores ...
Breaking Biology Technology: