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AgriLife scientist: Functional amino acids regulate key metabolic pathways
Date:11/19/2010

COLLEGE STATION - Functional amino acids play a critical role in the development of both animals and humans, according to a Texas AgriLife Research scientist.

In a journal article appearing in the American Society for Nutrition (Advances in Nutrition 1:31-37, 2010), Dr. Guoyao Wu, AgriLife Research animal nutritionist and senior faculty fellow in the department of animal science at Texas A&M University, calls for scientists to "think out of the box" and place more emphasis on this area of study.

"We need to move forward and capitalize on the potential of functional amino acids in improving health and animal production," he said.

A functional amino acid is an amino acid that can regulate key metabolic pathways to improve health, growth, development and reproduction of animals and humans, Wu said.

"This involves cell signaling through amino acids and their metabolites, and the metabolic pathways may include protein synthesis, antioxidative reactions and oxidation of energy substrates," he said. "A functional amino acid can be either a 'nonessential' or an 'essential' amino acid."

Past research emphasis has focused primarily on essential amino acids. However, Wu says both essential amino acids and non-essential amino acids should be taken into consideration.

"This is important when formulating balanced diets to maximize growth performance in livestock species, poultry and fish," he said. "It is also recommended that nonessential amino acids be provided to humans to prevent growth retardation and chronic diseases."

Wu's previous research discovered that arginine, an amino acid, contributes many positive benefits in growth and embryo development in pigs, sheep and rats. Arginine also aids in fighting obesity. Wu has identified this as an important area for expanded research on new amino acids and health.

"Currently in the U.S., more than 60 percent of adults are overweight or obese," he sa
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Contact: Dr. Guoyao Wu
g-wu@tamu.edu
979-845-1817
Texas A&M AgriLife Communications
Source:Eurekalert

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