Navigation Links
Advancement in tissue engineering promotes oral wound healing
Date:2/2/2009

Tampa, Fla. (Feb. 3rd, 2009) Oral tissue engineering for transplantation to aid wound healing in mouth (oral cavity) reconstruction has taken a significant step forward with a Netherlands-based research team's successful development of a gum tissue (gingival) substitute that can be used for reconstruction in the oral cavity. Their work was reported in the current issue of Cell Transplantation (17:10/11).

According to the study's lead author, Dr. Susan Gibbs of the VU University Medical Centre in Amsterdam, skin substitutes have been far more advanced than oral gingiva substitutes and, until now, no oral tissue-engineered products have been available for clinical applications. The team was the first to develop an autologous (same patient) full thickness skin substitute that Dr. Gibbs says is "proving to be very successful." However, they wanted to develop an autologous, full thickness oral substitute with the correct oral characteristics.

"Reconstructive surgery within the oral cavity is required during tumor excision, cleft palate repair, trauma, repair of diseased tissue and for generating soft tissue around teeth and dental implants," explained Dr. Gibbs. "Drawbacks of using skin as an autograft material in the oral cavity include bulkiness, sweating and hair formation and the limited amount of donor tissue available."

Their current study was aimed at constructing analogous, full-thickness oral substitutes in a similar manner to their skin substitute while maintaining the needed characteristics for successful oral transplantation. They used small amounts of patient oral tissue obtained from biopsies, then cultured and expanded the tissues in vitro over a three-week period.

Results of their study with a small number of patients showed that the gingiva substitute was "promising" and supported the need to carry out a larger patient study in the future.

"This study emphasized the importance of closely matching
'/>"/>

Contact: Dr. Susan Gibbs
s.gibbs@vumvc.nl
Cell Transplantation Center of Excellence for Aging and Brain Repair
Source:Eurekalert

Page: 1 2

Related biology news :

1. Frontiers in Optics presents scientific advancements
2. UC Irvine receives $2.18M to explore nano advancements in DNA sequencing
3. Leading researchers and experts gather to discuss latest advancements in drug discovery
4. American Association for the Advancement of Science honors four Iowa Staters
5. 13 UCR faculty members recognized by American Association for the Advancement of Science
6. A step toward tissue-engineered heart structures for children
7. Researchers create system to build transplant tissue
8. Chloroplast f and m Thioredoxins Discovered in Nonphotosynthetic Tissues
9. Natural product discovery by Cleveland medical researchers blocks tissue destruction
10. Knocking out cell receptor may help block fat deposits in tissues, prevent weight gain
11. Intravenous gene therapy protects normal tissue of mice during whole-body radiation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/21/2014)... (SACRAMENTO, Calif.) Mothers of children with autism are significantly ... during their pregnancies than the mothers of children who ... UC Davis MIND Institute has found. , Low iron ... autism in the child if the mother was 35 ... or if she suffered from metabolic conditions such as ...
(Date:9/21/2014)... In recent years, new strains of bacteria have emerged ... these superbugs, including drug-resistant forms of tuberculosis and staphylococcus, ... at least 23,000. Despite the urgent need for new ... antibiotics in the past decade. , MIT engineers have ... Using a gene-editing system that can disable any target ...
(Date:9/19/2014)... Call it the Jimmy Durante of dinosaurs ... nasal profile. The new dinosaur, named Rhinorex ... University and Brigham Young University, lived in what ... during the Late Cretaceous period. , Rhinorex, which ... and a close relative of other Cretaceous hadrosaurs ...
Breaking Biology News(10 mins):Mothers of children with autism less likely to have taken iron supplements 2Battling superbugs 2Battling superbugs 3Battling superbugs 4New hadrosaur noses into spotlight 2
... to the evolutionary puzzle to explain why certain mammal families ... In research published in Proceedings of the Royal Society ... Dr Alistair Evans proposed a new theory explaining the diversity ... around two grams, to the blue whale which clocks in ...
... June 24, 2013 /PRNewswire-iReach/ -- Strax Rejuvenation, one of the ... just announced a "Get Ready for Summer" promotion that features ... (Photo: http://photos.prnewswire.com/prnh/20130624/CG36984 ) For ... syringe instead of the usual price of $550; and Radiesse ...
... from a rare metabolic complication during pregnancy are programmed to ... Journal of Clinical Investigation . The study is ... babies born to mothers with intrahepatic cholestasis of pregnancy (ICP), ... by the build-up of bile acids in the bloodstream. ...
Cached Biology News:From minute to massive -- mammal size evolution explained 2Non-Surgical Procedures are Now Available at a Discount at Strax Rejuvenation 2Non-Surgical Procedures are Now Available at a Discount at Strax Rejuvenation 3Rare pregnancy condition programs babies to become overweight in later life 2Rare pregnancy condition programs babies to become overweight in later life 3
(Date:9/22/2014)... 22, 2014 Pearl's Premium Ultra Low ... drought tolerant grass seed this week with the release ... announcement coincides with the fact that it is time ... many believe. , As of the date 6/4/13, ... reviews by industry experts and the media including: ...
(Date:9/22/2014)... tiny cell fragments whose job it is to stop ... nucleus. But they can "feel" the physical environment around ... , Platelets respond to surfaces with greater stiffness by ... on" other platelets and other components of the clotting ... we give them credit for, in that they are ...
(Date:9/22/2014)... create a highly sensitive chemical sensor based on the ... electronic properties that the researchers were able to exploit ... times. , The study is available online in advance ... Salehi- Khojin, asst professor of mechanical and industrial engineering ... Bijandra Kumar, post doc where they are doing research ...
(Date:9/22/2014)... Topical BioMedics, Inc., is celebrating 20 ... their suffering, restoring hope an quality of life and ... possible because of the innovative cellular biomedicines research that ... reality. , The company was founded in 1994 ... (president, chief of research, and Topricin inventor), Aurora Paradise ...
Breaking Biology Technology:Pearl's Premium Ultra Low Maintenance Lawn Seed Announces A Major Breakthrough In Drought Tolerant Grass Seed 2Platelets modulate clotting behavior by 'feeling' their surroundings 2Graphene imperfections key to creating hypersensitive 'electronic nose' 2Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 2Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 3Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 4Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 5Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 6
... insiders knowingly misrepresented the ... company ... Shapiro filed a,proposed class-action lawsuit on behalf of CellCyte Genetics ... company and chief executive officer Gary A.,Reys, background, causing company ...
... Jan. 18 Brinks Hofer Gilson & Lione, one ... States, is,pleased to announce that 21 of its attorneys ... survey conducted by Law & Politics magazine.,Additionally, 11 Brinks ... Martin Addy, chair of the Appellate Group at Brinks, ...
... Record 20 Million Signatures Collected on myLifetime.com in ... Bipartisan Breast Cancer Patient Protection Act Allows Women Choice to, Recuperate ... ... Cancer Surgery -, NEW YORK, Jan. 18 "Desperate ...
Cached Biology Technology:Hagens Berman Sobol Shapiro: Lawsuit Filed Against CellCyte Genetics Corporation 2Hagens Berman Sobol Shapiro: Lawsuit Filed Against CellCyte Genetics Corporation 3Twenty-One Brinks Hofer Gilson & Lione Attorneys Named 2008 'Illinois Super Lawyers' 2Emmy(R)- and Golden Globe(R)-Nominated Actress Marcia Cross to Join Lifetime Networks and Members of Congress From Both Parties at Capitol Hill Press Conference 2Emmy(R)- and Golden Globe(R)-Nominated Actress Marcia Cross to Join Lifetime Networks and Members of Congress From Both Parties at Capitol Hill Press Conference 3
Request Info...
Human acetylcholine receptor (AChR)-alpha. Exhibits homogenous, high affinity,binding to the receptor. Binds weakly to a64-78. Inhibits binding of many,myasthenia gravis sera to human AChR....
...
Hybridization Buffer 3.6 ml...
Biology Products: