Navigation Links
Advance toward earlier detection of melanoma

Scientists are reporting development of a substance to enhance the visibility of skin cancer cells during scans with an advanced medical imaging system that combines ultrasound and light. The hybrid scanner could enable doctors to detect melanoma, the most serious form of skin cancer, in its earliest and most curable stages, the report in the monthly journal ACS Nano indicates.

Lihong Wang, Younan Xia, and colleagues point out that early diagnosis is key to improving survival in patients with melanoma. The five-year survival rate for melanoma is about 98 percent if detected early but can be as low as 15 percent when detected at an advanced stage. Existing imaging techniques for early detection of melanoma produce low-quality images, can "see" only a fraction of an inch below the skin, and use potentially harmful radioactive materials. A promising new technique called photoacoustic tomography (PAT) can overcome these problems. The system shoots light into tumors, which slightly heats up the cancer cells and produces high frequency sound waves that provide images of the tumor. But the PAT system lacks an optimal contrast agent that can easily enter skin cancer cells and make them visible.

The scientists developed such an agent by attaching a peptide (one of the building blocks of proteins) that targets skin cancer cells to gold "nanocages." These hollow gold nanoparticles have a box-like shape and are barely 1/50,000th the width of a human hair. When injected into mice with skin cancer, the nanocages improved the image quality of the cancer cells by three-fold compared to nanoparticles lacking the peptide. The gold nanocages also show promise as a way to kill skin cancer cells using heat or anti-cancer drugs, they add.


Contact: Michael Bernstein
American Chemical Society

Page: 1

Related biology news :

1. Stevens awarded $1M for advanced biofuels research
2. Taking the next step toward advanced artificial limbs
3. Advance offers revolution in food safety testing
4. Sig-Tec(R) and BIO-key(R) Deliver Advanced Biometric Security Solution to Ohio County Law Enforcement Agency
5. New data resource to advance computer-aided drug design
6. Annual Bibliography of Significant Advances in Dietary Supplement Research 2007
7. New book includes advances in the science and practice of transfusion and transplantation
8. State fund advances titanium powder research, 9 other Iowa State projects
9. Brandeis and Smart Balance team up to advance heart-healthy research
10. Marine invasive species advance 50km per decade, World Conference on Marine Biodiversity told
11. Clemson researchers advance nano-scale electromechanical sensors
Post Your Comments:
Related Image:
Advance toward earlier detection of melanoma
(Date:9/29/2015)... -- iDAvatars is excited to be named one of the first ... official announcement was recently made at an invite-only IBM ... San Francisco , where iDAvatars presented a demo of ... "It is both an honor and a privilege to ... market the cognitive power of IBM Watson in our product, ...
(Date:9/28/2015)... , September 28, 2015 ... expected to reach USD 12.03 billion by 2020, growing ... Technological advancements such as Backside Illumination (BSI) technique to ... over the forecast period.      (Logo: ... of the chip to reduce loss and, thus, reduce ...
(Date:9/26/2015)... -- Results of a TactioRPM pilot project in a ... Stanford Medicine X Conference. In a presentation titled ... Devices and Pharmacogenomics", Roger Simard , Pharmacist ... senior patients equipped with connected health devices and ... TactioRPM remote patient monitoring platform were empowered to ...
Breaking Biology News(10 mins):
(Date:10/12/2015)... Belgium , Oct. 12, 2015 ... full results from a completed clinical study of its NuQ ... been published in the online issue of Clinical Epigenetics ... peer-reviewed study was conducted in collaboration with Lund ... by Roland Andersson , MD, PhD, Professor of Surgery ...
(Date:10/10/2015)... 10 octobre 2015 Le 8 octobre, l,honorable Doris ... Registre du Congrès sa déclaration de soutien à ... autour du plasma (IPAW), qui se tiendra du ... Plasma Protein Therapeutics Association (PPTA) et ... , Sensibiliser l,opinion publique mondiale autour du ...
(Date:10/9/2015)... DIEGO , Oct. 9, 2015  DePuy Synthes ... Flex with Q-PACK ®  Technology**, the only ... in trauma-related extremity procedures (foot and ankle, hand and ... announcement was made here at the 2015 Orthopaedic Trauma ... (provides a natural scaffold for new bone growth) and ...
(Date:10/8/2015)... PALM BEACH, Fla. , Oct. 8, 2015 /PRNewswire/ ... leader in synthetic biology, today announced the appointment of ... Head of Environment Sector, succeeding Nir Nimrodi ... Development.  Mr. Vaillancourt will direct Intrexon,s endeavors to generate ... North America , where he held a ...
Breaking Biology Technology: