Navigation Links
Advance toward a breath test to diagnose multiple sclerosis
Date:10/26/2011

Scientists are reporting the development and successful tests in humans of a sensor array that can diagnose multiple sclerosis (MS) from exhaled breath, an advance that they describe as a landmark in the long search for a fast, inexpensive and non-invasive test for MS -- the most common neurological disease in young adults. Their report appears in the journal ACS Chemical Neuroscience.

Hossam Haick and colleagues report that doctors now diagnose MS based on its characteristic symptoms, which include muscle spasms, numbness, coordination problems and slurred speech. One common tool for confirming the diagnosis and making informed decisions on treatment is magnetic resonance imaging (MRI) of the brain. Another tool is a lumbar puncture or "spinal tap" to analyze the fluid that bathes the brain and spinal cord. But MRI scans are costly, and lumbar punctures are invasive.

To overcome these obstacles, the researchers have identified volatile organic compounds that can be associated with MS from exhaled breath. Based on these findings, the researchers developed a new sensor array that can diagnose MS by analyzing the determined chemical compounds that appear in the breath of MS patients. Using the developed sensors, the researchers carried out a proof-of-concept clinical study on 34 MS patients and 17 healthy volunteers and found that the developed sensors are just as accurate as a spinal tap but without the pain or the risk of side effects. "The results presented here open new frontiers in the development of fast, noninvasive and inexpensive medical diagnosis tools for detection of chronic neurological diseases," the scientists stated. "The results could serve as a launching pad for the discrimination between different subphases of stages of multiple sclerosis as well as for the identification of multiple sclerosis patients who would respond well to immunotherapy." A large clinical study with the reported sensors is underway and will be reported in the future.


'/>"/>
Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Related biology news :

1. Leaf litter ants advance case for rainforest conservation in Borneo
2. Scientists report major advance in human antibody therapy against deadly Hendra virus
3. CHEO scientist advances biotherapeutics as published in Cancer Cell
4. JBEI identify new advanced biofuel as an alternative to diesel fuel
5. NHTSA Awards Takata-TruTouch $2.25M to Advance Worlds First Touch-based In-Vehicle Alcohol Detection Device
6. Seminar to explore advanced tools for unlocking treasures that lie right at the surface
7. A 3-D reconstructed image of neural dendritic trees using the advanced electron microscope technology
8. Recent trends show recessions effect on US advanced technology exports
9. Green light for EU co-funding of TUM Institute for Advanced Study fellowships
10. New technique advances bioprinting of cells
11. Life Sciences Discovery Fund helps launch 3 programs to advance health research and development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/13/2017)... 2017 UBM,s Advanced Design and Manufacturing event ... emerging and evolving technology through its 3D Printing and ... alongside the expo portion of the event and feature ... focused on trending topics within 3D printing and smart ... event will take place June 13-15, 2017 at the Jacob ...
(Date:4/11/2017)... N.Y. , April 11, 2017 ... fingerprints, but researchers at the New York University ... College of Engineering have found that partial similarities ... security systems used in mobile phones and other ... thought. The vulnerability lies in the ...
(Date:4/5/2017)... Today HYPR Corp. , leading innovator ... of the HYPR platform is officially FIDO® Certified ... architecture that empowers biometric authentication across Fortune 500 enterprises ... over 15 million users across the financial services industry, ... product suites and physical access represent a growing portion ...
Breaking Biology News(10 mins):
(Date:8/24/2017)... ... August 24, 2017 , ... A new objective ... suffering concussion symptoms in a recent study published in Optometry and Vision ... predicting concussion history with 92 percent accuracy using the Diopsys® NOVA™ ERG and ...
(Date:8/23/2017)... and CARDIFF, UK (PRWEB) , ... August 23, ... ... that provides neurosurgeons with the ability to manipulate 3D models of pediatric patients’ ... big step forward” by editors of the Journal of Medical Imaging. The advance ...
(Date:8/23/2017)... ... August 22, 2017 , ... ... market innovators, Munich Re , one of the world’s leading reinsurers and ... investor that accelerates the development of technologies to support the U.S. intelligence community, ...
(Date:8/23/2017)... ... August 23, 2017 , ... ... and beer sectors, South African bio-technology company, Green Cell Technologies® (GCT®), ... Its technology is directly challenging current outdated ‘pressing’ methods, ushering in a new ...
Breaking Biology Technology: