Navigation Links
Adult stem cell breakthrough
Date:11/19/2008

even-centimetre tracheal segment was donated by a 51-year-old transplant donor who had who had died of cerebral haemorrhage. Spain has a policy of assumed consent for organ donation. Using a new technique developed in Padua University, the trachea was decellularised over a six-week period so that no donor cells remained.

Stem cells were obtained from the recipient's own bone marrow, grown into a large population in Professor Martin Birchall's lab at the University of Bristol, and matured into cartilage cells (chondrocytes) using an adapted method originally devised for treating osteoarthritis by Professor Anthony Hollander at the University of Bristol.

The donor trachea was then seeded with chondrocytes on the outside, using a novel bioreactor which incubates cells, developed at the Politecnico di Milano, Italy, allowing them to migrate into the tissue under conditions ideal for each individual cell type. In order to replicate the lining of the trachea, epithelial cells were seeded onto the inside of the trachea using the same bioreactor.

Four days after seeding, the graft was used to replace the patient's left main bronchus. The operation was performed in June 2008 at the Hospital Clinic, Barcelona, by Professor Paolo Macchiarini of the University of Barcelona.

Professor Macchiarini, lead author on the paper, said: "We are terribly excited by these results. Just four days after transplantation the graft was almost indistinguishable from adjacent normal bronchi. After one month, a biopsy elicited local bleeding, indicating that the blood vessels had already grown back successfully".

Martin Birchall, Professor of Surgery at the University of Bristol, added: "Surgeons can now start to see and understand the very real potential for adult stem cells and tissue engineering to radically improve their ability to treat patients with serious diseases. We believe this success has proved that we are on the verge of a new age in su
'/>"/>

Contact: Cherry Lewis
cherry.lewis@bristol.ac.uk
44-077-294-21885
University of Bristol
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. SNPs affect folate metabolism in study of Puerto-Rican adults
2. Scripps research scientists identify compounds for stem-cell production from adult cells
3. Turtle doves commit adultery
4. Efavirenz-based initial therapies associated with better outcomes in HIV-infected adults
5. NIH EUREKA award funds research at WPI aimed at turning adult skin cells into stem-like cells
6. Researchers discover atomic bomb effect results in adult-onset thyroid cancer
7. Adults who eat eggs for breakfast lose 65 percent more weight
8. Adult stem cells activated in mammalian brain
9. Childrens Memorial Hospital of Chicago receives a grant from BioMarin to support adult PKU outreach
10. Salk researchers reprogram adult stem cells in their natural environment
11. U of M researchers discover gene linked to adult-onset obesity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... 2014  Privacy Advocate and Senior Staff Attorney at ... joins the lineup of biometric and mobile commerce experts ... Executive Summit in Tampa, Florida ... speakers include Steven Rahman, Director, Technology and Strategy at Samsung, ... The theme of this year,s event is Mobility at ...
(Date:8/28/2014)... for measuring and imaging how quickly blood flows in ... how drug abuse affects the brain, which may aid ... to better treatment options for recovering drug addicts. The ... Stony Brook University in New York, USA and the ... The Optical Society,s (OSA) open-access journal Biomedical ...
(Date:8/28/2014)... mould in homes could pose a significant health risk to ... the Journal of Allergy and Clinical Immunology . , ... different countries, the research has found that the presence of ... asthma sufferers, as well as increasing the likelihood of developing ... team at the University of Exeter Medical School and is ...
Breaking Biology News(10 mins):Biometrics UnPlugged Welcomes the Electronic Frontier Foundation's Jennifer Lynch to the Mobility at the Crossroads of Commerce and Privacy Summit 2This is your brain's blood vessels on drugs 2This is your brain's blood vessels on drugs 3Indoor mold poses health risk to asthma sufferers 2
... Nanotechnology holds great promise for the future of ... the safety of nanoproducts may limit these important ... to the U.S. House Committee on Science and ... for Biological and Environmental Nanotechnology (CBEN) and executive ...
... infections, may be a strong weapon in the ... to an article in the November issue of ... seen as exotic diseases, but this is changing ... infections are a major problem for the immunocompromised, ...
... MEAS ), a designer and manufacturer of sensors ... German,Business Tax Reform 2008 on current year financial statements. ... effective on August,17, 2007, reduces the corporate income tax ... German tax rate from approximately 39% to 31%.,Although this ...
Cached Biology News:Rice University expert calls for coordination in nanotechnology research 2Gamma interferon could aid fight against fungal infections 2Measurement Specialties, Inc. Announces Impact of 'German Business Tax Reform 2008' Resulting in Lower Combined German Tax Rate - Impacts 2Q08 Reported Financial Results 2Measurement Specialties, Inc. Announces Impact of 'German Business Tax Reform 2008' Resulting in Lower Combined German Tax Rate - Impacts 2Q08 Reported Financial Results 3
(Date:8/28/2014)... CA (PRWEB) August 28, 2014 ... is offering a promotion for Eppendorf Safe ... customers to purchase the highest quality tubes at ... are ideal for customers doing chemical, medical, pharmaceutical, ... technicians who are not regularly able to afford ...
(Date:8/27/2014)... Varian Medical Systems today broke ground ... Lake City manufacturing facility and allow for the consolidation ... create 1,000 new full time jobs in the state ... home to hardworking people with immense engineering and technical ... success in the manufacturing of our state-of-the-art X-ray technology,” ...
(Date:8/27/2014)... BOSTON , Aug. 27, 2014 Rhythm, ... diseases and genetic deficiencies that result in metabolic disorders, ... on Form S-1 with the U.S. Securities and Exchange ... of shares of its common stock. The number of ... the offering have not yet been determined. ...
(Date:8/27/2014)... NEW YORK , Aug. 27, 2014 ... market research report is available in its ... Market 2014-2018 http://www.reportlinker.com/p02316661/Global-Biodegradable-Packaging-Materials-Market-2014-2018.html ... Biodegradable materials are materials that are readily ... packaging differs from conventional non-degradable packaging in ...
Breaking Biology Technology:Eppendorf Safe Lock Centrifuge Tube Promotion Now Available at Major Pipette Distributor Pipette.com 2Eppendorf Safe Lock Centrifuge Tube Promotion Now Available at Major Pipette Distributor Pipette.com 3Varian Medical Systems Groundbreaking on Facility Expansion Triggers Influx of New Jobs to Salt Lake 2Varian Medical Systems Groundbreaking on Facility Expansion Triggers Influx of New Jobs to Salt Lake 3Rhythm Files Registration Statement for Proposed Initial Public Offering 2Global Biodegradable Packaging Materials Market 2014-2018 2Global Biodegradable Packaging Materials Market 2014-2018 3Global Biodegradable Packaging Materials Market 2014-2018 4Global Biodegradable Packaging Materials Market 2014-2018 5Global Biodegradable Packaging Materials Market 2014-2018 6Global Biodegradable Packaging Materials Market 2014-2018 7
... compounds to reduce inflammation and strengthen host defences could be ... could be the most successful treatment for IBD to date, ... of the Journal of Medical Microbiology . IBD ... and bloody diarrhoea and abdominal pain. It is an emerging ...
... This release is available in German . ... research facility CNRS, south of Paris, are using electric fields ... store data permanently. This principle could not only improve random ... generation of electronic devices. This new kind of memory ...
... ... on Patent Quality, Not Quantity , ... Chicago, IL (PRWeb) January 19, 2010-- Ocean Tomo, LLC, the Chicago-based ... Bloomberg BusinessWeek. , , , , ,The study, which ranks the 25 companies with ...
Cached Biology Technology:Promising probiotic treatment for inflammatory bowel disease 2Data at the end of the tunnel 2Ocean Tomo Study Ranks Top 25 Most Inventive Companies for Bloomberg BusinessWeek, 2Ocean Tomo Study Ranks Top 25 Most Inventive Companies for Bloomberg BusinessWeek, 3Ocean Tomo Study Ranks Top 25 Most Inventive Companies for Bloomberg BusinessWeek, 4
Rat Normal Multiple Tissue Array 1 slide...
... LiCl precipitation offers major advantages over other ... precipitate DNA, protein or carbohydrates. It is the ... or cDNA synthesis from RNA preparations. Note, LiCl ... total RNA isolations. If the RNA is to ...
...
...
Biology Products: