Navigation Links
Adaptation in mole blood aids tunnelling
Date:7/19/2010

'Super hemoglobin' allows moles to thrive underground. Researchers writing in the open access journal BMC Evolutionary Biology have made the first identification of an adaptation in the blood of Eastern moles which allows more efficient transport of carbon dioxide, facilitating the moles' burrowing behavior.

Kevin Campbell from the University of Manitoba, Canada, worked with a team of researchers to study the blood of three underground species of North American moles. He said, "Unlike terrestrial animals, moles are routinely exposed to conditions of low oxygen and high carbon dioxide. Burrowing is difficult in itself, but is made even more challenging by the requirement to re-breathe their own expired air. We've found that one species, the Eastern mole, appears to be uniquely adapted to underground life through the evolution of a special kind of hemoglobin in their blood that greatly enhances its carbon dioxide carrying capacity".

The researchers determined the genetic code for different hemoglobin components in the three mole species and measured how well these components bind to their usual target molecules. They also tested the oxygen binding properties of whole blood samples. Speaking about the results, Campbell said, "It has been speculated that the main mechanism for the moles adaptation to subterranean life revolves around the molecule 2,3-diphosphoglycerate, or DPG, that modulates hemoglobin's oxygen binding inside the blood cells. However, in the hemoglobin of the eastern mole, the key sites which would normally bind DPG are deleted, thereby allowing for the binding of additional carbon dioxide molecules".

Adds co-author Roy Weber, University of Aarhus, Denmark, "It would be interesting to see if the hemoglobins of other burrowing species exhibit comparable specializations". The team envisions that this line of research could lead to the development of improved artificial human blood substitutes with specially engineered properties.


'/>"/>

Contact: Graeme Baldwin
graeme.baldwin@biomedcentral.com
44-203-192-2165
BioMed Central
Source:Eurekalert

Related biology news :

1. Genetic adaptations key to microbes survival in challenging environment
2. Scripps Florida scientists show lifeless prions capable of evolutionary change and adaptation
3. Experiential learning teaches change and adaptation
4. Phylogenetic analysis of Mexican cave scorpions suggests adaptation to caves is reversable
5. Adaptation is (not) in the eye of the beholder
6. Scientist plans to test for blood pressure genes affected by age
7. Discovery of natural compounds that could slow blood vessel growth
8. New blood test for Down syndrome
9. On the trail of a targeted therapy for blood cancers
10. Lower your blood pressure, hydrate your skin and reduce dental plaque -- with chocolate?
11. Building the blood-brain barrier
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2017)... GENOA, Italy , May 23, 2017  Hunova, the first robotic ... and trunk, has been officially launched in Genoa, Italy ... Europe and the USA . The ... launched on the market by the IIT spin-off Movendo Technology thanks to ... view the Multimedia News Release, please click: ...
(Date:4/19/2017)... 2017 The global military biometrics ... marked by the presence of several large global players. ... five major players - 3M Cogent, NEC Corporation, M2SYS ... nearly 61% of the global military biometric market in ... global military biometrics market boast global presence, which has ...
(Date:4/11/2017)... BEACH GARDENS, Fla. , April 11, 2017 ... identity management and secure authentication solutions, today announced ... contract by Intelligence Advanced Research Projects Activity (IARPA) ... for IARPA,s Thor program. "Innovation has ... onset and IARPA,s Thor program will allow us ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... , ... October 12, 2017 , ... ... today announced the three Winners and six Finalists of the 2017 Blavatnik Regional ... by the Blavatnik Family Foundation and administered by the New York Academy of ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... a United States multicenter, prospective clinical study that demonstrates the accuracy of ... capable of identifying clinically significant acute bacterial and viral respiratory tract infections ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... partners with the pharmaceutical and biotechnology industries to improve patient outcomes and quality ... Several trends in analytical testing are being attributed to new regulatory requirements for ...
(Date:10/11/2017)... N.C. (PRWEB) , ... October 11, 2017 , ... ... ARCS® Foundation President Andi Purple announced Dr. Suneel I. Sheikh, the co-founder, ... ( ASTER Labs ), Inc. has been selected for membership in ARCS ...
Breaking Biology Technology: