Navigation Links
Adaptation in mole blood aids tunnelling
Date:7/19/2010

'Super hemoglobin' allows moles to thrive underground. Researchers writing in the open access journal BMC Evolutionary Biology have made the first identification of an adaptation in the blood of Eastern moles which allows more efficient transport of carbon dioxide, facilitating the moles' burrowing behavior.

Kevin Campbell from the University of Manitoba, Canada, worked with a team of researchers to study the blood of three underground species of North American moles. He said, "Unlike terrestrial animals, moles are routinely exposed to conditions of low oxygen and high carbon dioxide. Burrowing is difficult in itself, but is made even more challenging by the requirement to re-breathe their own expired air. We've found that one species, the Eastern mole, appears to be uniquely adapted to underground life through the evolution of a special kind of hemoglobin in their blood that greatly enhances its carbon dioxide carrying capacity".

The researchers determined the genetic code for different hemoglobin components in the three mole species and measured how well these components bind to their usual target molecules. They also tested the oxygen binding properties of whole blood samples. Speaking about the results, Campbell said, "It has been speculated that the main mechanism for the moles adaptation to subterranean life revolves around the molecule 2,3-diphosphoglycerate, or DPG, that modulates hemoglobin's oxygen binding inside the blood cells. However, in the hemoglobin of the eastern mole, the key sites which would normally bind DPG are deleted, thereby allowing for the binding of additional carbon dioxide molecules".

Adds co-author Roy Weber, University of Aarhus, Denmark, "It would be interesting to see if the hemoglobins of other burrowing species exhibit comparable specializations". The team envisions that this line of research could lead to the development of improved artificial human blood substitutes with specially engi
'/>"/>

Contact: Graeme Baldwin
graeme.baldwin@biomedcentral.com
44-203-192-2165
BioMed Central
Source:Eurekalert

Page: 1 2

Related biology news :

1. Genetic adaptations key to microbes survival in challenging environment
2. Scripps Florida scientists show lifeless prions capable of evolutionary change and adaptation
3. Experiential learning teaches change and adaptation
4. Phylogenetic analysis of Mexican cave scorpions suggests adaptation to caves is reversable
5. Adaptation is (not) in the eye of the beholder
6. Scientist plans to test for blood pressure genes affected by age
7. Discovery of natural compounds that could slow blood vessel growth
8. New blood test for Down syndrome
9. On the trail of a targeted therapy for blood cancers
10. Lower your blood pressure, hydrate your skin and reduce dental plaque -- with chocolate?
11. Building the blood-brain barrier
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2015)... SHENZHEN, China , 31 de julho de 2015 ... Genômica (ICG-10, www.icg-10.org ) será realizada pela BGI de ... China . A conferência está ... inauguração em 2006, a ICG se tornou uma das ... e um dos encontros científicos mais dinâmicos, entusiastas e ...
(Date:7/31/2015)... , July 31, 2015 The 10 th ... be held by BGI from October 22-25, 2015, in ... The conference is celebrating its 10 th anniversary this ... of the world,s most influential annual meetings in the ,omics, ... enjoyable scientific gatherings. ICG-10 focuses on recent ...
(Date:7/23/2015)... , July 23, 2015 Research ... addition of the "Global Outlook of the ... offering. The global biometrics market ... public and commercial applications owing to the uptake ... witness a transformation that enhances the growth of ...
Breaking Biology News(10 mins):A 10a. Conferência Internacional sobre Genômica (ICG-10) será em outubro 2A 10a. Conferência Internacional sobre Genômica (ICG-10) será em outubro 3The 10th International Conference on Genomics (ICG-10) to Open in October 2Global Outlook of the Biometrics Industry 2015 2Global Outlook of the Biometrics Industry 2015 3
... school students and teachers sounds like a witches brew for an ... Instead, these are the components that comprise the ... developed by researchers at Washington University in St. Louis and a ... Lars Angenent, Ph.D., assistant professor of ...
... a pair of proteins that work in concert to restart ... dormancy. The Hawley Lab has described the dual ... that awakens the long-dormant egg, allowing for production of a ... Dec. 4, 2007 issue of PLoS Biology. The ...
... may have begun in the protected spaces inside of layers ... new hypothesis. The hypothesis was developed by Helen Hansma, ... and a program director at the National Science Foundation. Hansma ... Dec. 4, at the annual meeting of the American Society ...
Cached Biology News:Microbial fuel cells turn on the juice 2Microbial fuel cells turn on the juice 3Stowers Institute's Hawley Lab identifies factors responsible for restart of meiotic cycle 2New hypothesis for origin of life proposed 2
(Date:8/3/2015)... 2015  Aethlon Medical, Inc. (Nasdaq: AEMD ), ... life-threatening diseases, today announced that it will host its ... on Thursday, August 13, 2015 at 4:30 p.m. Eastern ... the release of fiscal 2016 first quarter results.  A ... two hours after the call at the Investor Relations ...
(Date:8/3/2015)... , August 3, 2015 ... Study on 3D Cell Culture: Asia ... Persistence Market Research, the global 3D cell culture market was valued ... to expand at a CAGR of 29.1% to account ... Full Report with TOC:  http://www.persistencemarketresearch.com/market-research/3d-cell-cultures-market.asp 3D ...
(Date:7/31/2015)... , July 31, 2015 In today,s ... that help them drive positive health outcomes, improve ... source of patient care in their communities. At ... tradeshow and conference, AmerisourceBergen announced a new set ... Services Administration Organization and help independent pharmacies endure ...
(Date:7/31/2015)... ... July 31, 2015 , ... ... and quantification of partially hydrolyzed gluten in foods, has been accepted by AOAC ... method “Partially Hydrolyzed Gluten in Fermented Cereal-Based Products by R5 Competitive ELISA,” based ...
Breaking Biology Technology:Aethlon Medical To Host First Quarter Fiscal 2016 Investor Call on August 13, 2015 2Global 3D Cell Culture Market Will Reach US$ 2,717.6 Million by 2020: Persistence Market Research 2Global 3D Cell Culture Market Will Reach US$ 2,717.6 Million by 2020: Persistence Market Research 3Global 3D Cell Culture Market Will Reach US$ 2,717.6 Million by 2020: Persistence Market Research 4AmerisourceBergen Unveils Suite of Enhanced Capabilities for Independent Pharmacies at ThoughtSpot 2015 2AmerisourceBergen Unveils Suite of Enhanced Capabilities for Independent Pharmacies at ThoughtSpot 2015 3RIDASCREEN® Competitve Gliadin Receives AOAC Official First Action Status 2
... Lam Yeng Ming, 35, a lecturer with the School of ... has been awarded one of the three inaugural L,Oral Singapore ... Prof Lam and the two other women scientists have each ... contributions of women scientists to the advancement of science and ...
... , , RICHMOND, Calif., Sept. 2 ... that it will present at the BioCentury Thomson Reuters Newsmakers in ... am EDT. , , A live audio webcast ... webpage at www.transcept.com . , , ...
... , BOULDER, Colo., Sept. 2 LENA Foundation ... percent for children 24 to 48 months. LAS - the first automatic ... accurate than other autism screens currently available to parents and clinicians. , ... "We,re thrilled with this leap in accuracy, especially on the eve ...
Cached Biology Technology:NTU professor bags inaugural award honoring women in science 2NTU professor bags inaugural award honoring women in science 3Transcept Pharmaceuticals to Present at the BioCentury Thomson Reuters Newsmakers in the Biotech Industry Conference on September 16, 2009 2Transcept Pharmaceuticals to Present at the BioCentury Thomson Reuters Newsmakers in the Biotech Industry Conference on September 16, 2009 3Transcept Pharmaceuticals to Present at the BioCentury Thomson Reuters Newsmakers in the Biotech Industry Conference on September 16, 2009 4Advancement Made in Automatic Autism Screen Increases Accuracy to 91%, Scheduled for Release This Month 2Advancement Made in Automatic Autism Screen Increases Accuracy to 91%, Scheduled for Release This Month 3
...
Mouse monoclonal [2Q2147] to Aequorin ( Abpromise for all tested applications)....
Phosphotyrosine IgG mouse monoclonal antibody: Alkaline Phosphatase conjugate...
... mixed TAMRA isomers are predominantly used for ... preferred for labeling peptides and nucleotides because ... that is often required in the conjugation ... 6-TAMRA for labeling peptides and proteins. 6-TAMRA ...
Biology Products: