Navigation Links
Activated stem cells in damaged lungs could be first step toward cancer
Date:5/26/2009

ed, the investigators were able to show that the abundant population of progenitor cells that normally maintain the epithelial layer in the lung could be rapidly wiped out with a strong chemical, naphthalene. Then the rare proliferative cells became active and grew into large patches.

The researchers at Duke and Cancer Research UK used a unique whole-lung imaging method to examine and identify the location of stem cells in the lung tissue of mice, and determine the role they play in both healthy and damaged mouse lungs.

They found that, while the stem cells don't appear to be involved in the normal maintenance of healthy or moderately injured lungs, they do play a vital role in repairing severely damaged lungs.

Even though this repair mechanism is important for restoring lung function, it can come at a price. An acquired mutation in that rare cell or its descendants leads to clonal patches of many identical cells. Secondary mutations in any one of these cells may provide the signals needed for unregulated cell growth and tumor progression.

"This work provides a plausible mechanism to account for this type of event that we previously didn't have," Stripp said.


'/>"/>

Contact: Mary Jane Gore
mary.gore@duke.edu
919-660-1309
Duke University Medical Center
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Parus Interactive Awarded Patent for Speech-Activated Remote System Management
2. bioMETRX, Inc. Partners with Biometric Solutions, LLC to Deliver Next Generation Finger Activated Technology
3. Adult stem cells activated in mammalian brain
4. ESF EURYI award winner aims to stop cancer cells reading their own DNA
5. Newly created cancer stem cells could aid breast cancer research
6. AIDS interferes with stem cells in the brain
7. Clemson scientists shed light on molecules in living cells
8. Social habits of cells may hold key to fighting diseases
9. UF scientists reveal how dietary restriction cleans cells
10. Human derived stem cells can repair rat hearts damaged by heart attack
11. Scientists identify embryonic stem cells by appearance alone
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Activated stem cells in damaged lungs could be first step toward cancer
(Date:6/24/2015)... 24, 2015  Synaptics Inc. (NASDAQ: SYNA ... today announced that Sharp has selected its industry-leading ... for its latest flagship smartphone device, the AQUOS ... million shipments of its fingerprint ID sensor technology, ... scalability and leadership in the biometrics market through ...
(Date:6/24/2015)... MARTIGNY, Switzerland , June 24, 2015 /PRNewswire/ ... strategic partnership with emerging biometric password solution one ... http://photos.prnewswire.com/prnh/20150623/225014LOGO one face in, ... offers a ground-breaking and affordable multifactor-authentication biometric answer ... speaker recognition technology, provided in partnership with KeyLemon, ...
(Date:6/23/2015)... Research and Markets( ... "Body-Worn Temperature Sensors Market - Global Industry ... - 2020" report to their offering. ... global body-worn temperature sensors market. The global body-worn ... basis of types, care setting, patient demographic, applications ...
Breaking Biology News(10 mins):Synaptics Brings Natural ID Technology to Sharp's Newest Flagship Smartphone 2KeyLemon Announces Partnership With Biometric Password Solution onefacein 2Body-Worn Temperature Sensors Market - Global Industry Analysis 2
... is available in German . , ... has developed a model, which identifies potential habitats and corridors ... Rheinland-Pfalz as an example, it was demonstrated that almost half ... enabling a maximum population of 1600 females. The model can ...
... is a link between alcohol consumption and increased risk of ... 5,870 young adult women. The study, published in ... found that the risk increased 3% for every additional alcoholic ... observe any increase in risk of seasonal allergic rhinitis according ...
... Achieves record biometric revenues and profitability, WALL, ... Board: BKYI), a leader in wireless public safety ... profitability and strong revenue growth for its second ... continuing operations for the quarter ended June 30,2008 ...
Cached Biology News:Let the cat keep chasing the mouse 2Let the cat keep chasing the mouse 3Let the cat keep chasing the mouse 4Alcohol is associated with risk of perennial allergic rhinitis 2BIO-key(R) Reports Profitability on Strong Revenue Growth for Second Quarter 2008 2BIO-key(R) Reports Profitability on Strong Revenue Growth for Second Quarter 2008 3BIO-key(R) Reports Profitability on Strong Revenue Growth for Second Quarter 2008 4BIO-key(R) Reports Profitability on Strong Revenue Growth for Second Quarter 2008 5
(Date:7/6/2015)... ... 2015 , ... Proove Biosciences , a commercial and ... Advisory Board meeting in Palm Springs, California. At the bi-annual meeting, the Medical ... new clinical practice and research ideas. The Board also discussed the development of ...
(Date:7/6/2015)... 6, 2015  Emdeon Inc. today announced ... agreement to acquire Altegra Health, a national ... combine data aggregation and analytics with unique ... actionable insights and improved management for value-based ... risk adjustment and quality analytics and Emdeon,s ...
(Date:7/6/2015)... Research and Markets ... the "Biotechnology for the Non-Biotechnologist" conference ... Non-Biotechnologist, ideal for non-Scientists and Scientists needing to ... of biotechnology. Ideal for Non-Scientists and ... techniques, and potential of biotechnology Why ...
(Date:7/6/2015)... leading Regulatory Service provider, today announced that it has opened a new ... . Navitas, expansion into Latin America will ... , the third largest economy in Latin America . ... ... regulatory professionals in close to or the same time zone and ...
Breaking Biology Technology:Proove Biosciences Gathers Key Opinion Leaders in Pain Management for Medical Advisory Board Meeting in Palm Springs, California 2Proove Biosciences Gathers Key Opinion Leaders in Pain Management for Medical Advisory Board Meeting in Palm Springs, California 3Emdeon to Acquire Altegra Health 2Emdeon to Acquire Altegra Health 3Emdeon to Acquire Altegra Health 4Navitas Launches Latin American Regulatory Operations Hub in Bogota, Colombia 2Navitas Launches Latin American Regulatory Operations Hub in Bogota, Colombia 3
... the Gladstone Institute of Neurological Disease (GIND) have uncovered ... (AD) and other neurodegenerative diseases. The results might lead ... examined a protein called tau that has been strongly ... author on the study. "Tau forms toxic protein aggregations ...
... Maui County officials at that time agreed with ... that someone with their experience in scrap metal ... In March of 2005, the headline of the Maui ... Stepping into this island-wide disaster was SOS Metals ...
... Sept. 22 Signal Genetics, a privately held predictive ... company will work with Array BioPharma to help push ... helping bring personalized medicine and companion diagnostics to patients ... and antibody producing cells. Signal Genetics, groundbreaking ...
Cached Biology Technology:Gladstone scientists identify strategy to reduce toxic proteins associated with Alzheimer's disease 2SOS Metals Island Recycling Sold to Schnitzer Steel Industries 2
... Morris Water MazeRecords animal movements in a ... subjects at once in a predefined sequence of ... instruments all built around a video camera, frame ... track two fields at once and up to ...
... Place AvoidanceIncludes all features of Tracker, plus ... a user defined subsection of the arena, and ... family of instruments all built around a video ... that can track two fields at once and ...
... Last innovation from Magnetofection technology, ... delivery system available. Simple, rapid and ... compatible and non toxic. Specifically designed ... gene silencing at very low doses ...
Denhardt's Solution is a mixture of blocking agents used in membrane-based hybridization protocols. The solution contains 1% Ficoll (type 400) 1% polyvinylpyrrolidone and 1% bovine serum albumin. Ste...
Biology Products: