Navigation Links
Accelerated bone turnover remains after weight loss
Date:7/28/2008

COLUMBIA, Mo. When a person is losing a significant amount of weight, they expect to notice changes in their body. However, they may overlook changes happening in their bones. During weight loss through calorie-restricted diets, bones are being remodeled - breaking down old bone and forming new bone - at an accelerated rate. At the same time, bone density is decreasing, causing increased fragility. In a new study, a University of Missouri researcher and collaborators at the University of Kansas found that the potentially harmful effects of weight loss on bone persist during weight maintenance following moderate weight loss.

Researchers examined protein markers of bone breakdown and formation in 37 obese, middle-aged adults who lost 20 percent of their body weight through a severe calorie-restricted diet. Protein markers, which are released during bone breakdown and formation, are used as indirect indicators of bone remodeling. During the 3-month weight-loss phase, bone remodeling was elevated, and bone formation and breakdown were imbalanced as a result of a low energy intake. After weight loss phase, bone remodeling remained elevated during the 9-month weight maintenance phase, but bone formation and breakdown appeared to be balanced.

"When people increased their calorie intake after weight loss, the bone remodeling markers did not respond and remained above what they were before weight loss," said Pam Hinton, associate professor of nutritional sciences in the MU College of Human Environmental Sciences. "However unlike the weight loss phase, it appeared that bone breakdown and bone formation were balanced. Rapid rates of bone remodeling, regardless of the balance of breakdown and formation, can increase bone fragility."

Hinton found that a greater reduction in body weight resulted in a greater increase in bone breakdown. Having a low-carbohydrate or a low-fat diet during the weight maintenance phase had no effect on bone rem
'/>"/>

Contact: Kelsey Jackson
JacksonKN@missouri.edu
573-882-8353
University of Missouri-Columbia
Source:Eurekalert

Page: 1 2

Related biology news :

1. New technique determines the number of fat cells remains constant in all body types
2. Chesapeake Bay ecosystem health remains poor, but slightly improved in 2007
3. Video released of rapid Alzheimers improvement after new immune-based treatment
4. Dioxin risk in soil and plant tissues after long-term biosolids application
5. Children born from frozen embryos weigh more and do better than those born after fresh transfer
6. Children born after donor insemination should be told as soon as possible about their conception
7. Resuscitation technique after brain injury may do more harm than good
8. Dwarf cloud rat rediscovered after 112 years
9. Pregnancy is possible after cancer treatment
10. Many African-Americans have a gene that prolongs life after heart failure
11. Breast cancers behave differently before and after the age of 70
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... devastate honeybees in Europe, Asia and the United States ... to be impacting native honeybee populations at this time, ... pests include including Nosema microsporidia and ... be resilient to these invasive pests, which suggests to ... Europe, Asia and the United States currently are not ...
(Date:4/17/2014)... hit on a novel method to help kidney ... most effective treatment possible., Kidney stones represent a ... world. If left untreated, apart from being particularly ... other complications. In many patients treated successfully, stone ... effective pathological approach to diagnosis and treatment needs ...
(Date:4/17/2014)... painted a stark warning on the possible effects of ... effect 32 times that of carbon dioxide. Now a ... act as fully regenerable electron acceptors which helps explain ... instead of being released to the atmosphere. However, there ... may enter into a vicious cycle to release large ...
Breaking Biology News(10 mins):East African honeybees are safe from invasive pests… for now 2East African honeybees are safe from invasive pests… for now 3Methane climate change risk suggested by proof of redox cycling of humic substances 2
... and vegetables instead of cookies and soda pop. Consider ... applaud a lunchtime workout rather than criticizing the cut ... encourages walking the stairs instead of riding the elevator. ... by Community Health Councils, Inc. (CHC) in Los Angeles ...
... Cold Spring Harbor Laboratory on Long Island have identified which ... the chief target of the widely prescribed antidepressant Prozac. This ... for depression, with fewer side effects, to be developed. , ... the factors that control how, when, and where new neurons ...
... tumor and settles in a new location, where it ... assays for this process, which is known as metastasis, ... across the surface of a matrix, traveling in a ... approach misses some crucial phenomena. , Working in the ...
Cached Biology News:UCLA study of community health project shows how group dynamics affect fitness, eating habits 2UCLA study of community health project shows how group dynamics affect fitness, eating habits 3Prozac's target revealed 23-D model reveals secrets of metastasis 2
(Date:1/14/2014)... a leading provider of strategic communications services to corporations and organizations ... the United States and Europe ... is returning to the firm,s Washington, D.C. ... than two years of service as Associate Commissioner for the Office ...
(Date:1/14/2014)... AUSTIN, Texas , Jan. 14, 2014 ... analyze and research medicinal plants and therapeutic derivatives ... industry, health professionals, and researchers about the challenges ... (Logo: http://photos.prnewswire.com/prnh/20100430/DC95601LOGO ) The ...
(Date:1/14/2014)... In recent years, growing suspicion about ... product development and promotion has led to unprecedented levels ... by concerns about the insidious impact of commercialization of ... fines to the world’s biggest pharmas for illegal marketing ...
(Date:1/14/2014)...   Kinaxis ®, provider of RapidResponse ®, a cloud-based ... planning ( S&OP ) service, is proud to be a ... be held at the Hilton San Diego Bayfront, January 30 ... Elisabeth Kaszas , Director of Supply Chain at Amgen, as ...
Breaking Biology Technology:Former FDA Associate Commissioner Returns To 3D Communications 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 4World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 5World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 6World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 7World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 8The Sunshine Act: Necessary Regulation or Unnecessary Dysregulation? New Life Science Webinar Hosted by Xtalks and IRB Services 2The Sunshine Act: Necessary Regulation or Unnecessary Dysregulation? New Life Science Webinar Hosted by Xtalks and IRB Services 3Event Alert: Kinaxis Customer to Present at the Biomanufacturing Summit "Supply Chain: Improving Network Effectiveness" 2
... Sweden, March 22, 2012 The new ... leading ion-channel research groups to meet the demand for ... Dynaflow Resolve System is an advanced automated perfusion system ... any ion channel current, using any cell type, and ...
... announced today the launch of its new BioSystem™ ... further enhance its global biological logistics services. Marken ... specimens transport and has designed a system with ... box size for optimum freight costs and dry ...
... 32 social scientists and researchers from around the world, ... have concluded that fundamental reforms of global environmental governance ... system. The scientists argued in the March 16 edition ... is now for a "constitutional moment" in world politics. ...
Cached Biology Technology:Cellectricon Launches Dynaflow® Resolve System Enabling Novel Ion Channel Assays 2Marken Launches Exclusive Shipping System for Specimen Logistics 2Fundamental steps needed now in global redesign of Earth system governance 2Fundamental steps needed now in global redesign of Earth system governance 3
... your samples with eArray and Agilents custom printing. ... own microarray designs that meet your specific biological ... delivery of your arrays in weeks, anywhere in ... creation application tool that enables you to design ...
... are used to study co-translational and ... events such as signal peptide cleavage, ... can be examined by the translation ... in the presence of these microsomal ...
Procollagen type I C-terminal propeptide (human, PICP)...
... Small Molecule Localization in Early Drug ... Get essential drug compound localization ... spectrometry. Protein Discoverys imaging mass spectrometry service ... them with histological images so you can ...
Biology Products: