Navigation Links
Academia should fulfill social contract by supporting bioscience startups, case study says
Date:10/25/2012

Universities not only provide the ideal petri dish for cultivating bioscience with commercial potential, but have a moral obligation to do so, given the opportunity to translate public funding into health and jobs, according to a new case study by UCSF researchers.

In an analysis published Oct. 24, 2012 in Science Translational Medicine, researchers at the California Institute for Quantitative Biosciences (QB3) assessed the impact of the institute's efforts over the past eight years in supporting entrepreneurs on the three UC campuses in which it operates: UCSF, UC Berkeley and UC Santa Cruz.

The study found that, by lowering the hurdle even very slightly for scientists to become entrepreneurs, the scientists were able to gain extraordinary traction in translating academic research into public benefit, generating 60 new companies in the first six years and attracting 75 new bioscience entrepreneurs in the last year alone.

"This fundamentally changes the way we think of academic science," said Douglas Crawford, PhD, assistant director of QB3 and senior author on the paper. "There is a distressing paucity of new drugs in the pipeline and a clear need for new economic engines in this country. This is a call to action to address that."

The paper cites the following essential support that universities can provide:

  • Bioscience-focused incubators
  • An open network approach that enables any entrepreneur to participate
  • Competitive seed funding options
  • Real-world mentoring that gives scientist a clear sense of market needs.

In the first six years since QB3 started supporting entrepreneurs at the UCSF Mission Bay campus, its growing network of incubators helped launch 60 new bioscience companies at UCSF and across the San Francisco Bay at UC Berkeley at a cost of $1 million per year. Of those, 56 are still in business, and 13 have moved beyond the incubator network or have been purchased by larger companies.

Together, those companies have created more than 280 jobs and attracted more than $230 million in either small business grants or venture capital funding for those companies, which are primarily focused on developing therapeutics, medical devices and research tools. That's a 38-fold return on investment, despite current negative trends in seed-stage investing, in addition to the public benefit of any products those companies generate.

The federal government invests $50 billion per year in academic research, including $23 billion for life sciences from the National Institutes of Health (NIH) alone, according to the paper. Both Baltimore, which is home to universities, and the San Francisco Bay Area receive about $2 billion annually in government research and development funding, yet productivity as measured by high-tech startups was 20-fold higher in the San Francisco area than Baltimore, the analysis found.

"This is clearly not an issue of how much funding is coming to the region. It's an issue of how we think about our social contract," said Regis B. Kelly, PhD, UCSF professor of biochemistry and biophysics, executive director of QB3 and a co-author on the paper. "Most people would say the public good a university offers is in providing research and education, but if we truly want to support the public with the benefits of science, we need to stop seeing economic growth and new medications as an inadvertent byproduct of academic research."

Many U.S. universities, including UCSF, are exploring ways to work with the private sector, with the multiple goals of invigorating research on campus, expediting drug development and ultimately improving the therapies that make it to the market.

That's a relatively new way of thinking, though, and one that often has been met with both skepticism and charges of conflicts of interest by those who believe science should be completely devoid of commercial influences.

"We have a fundamental charge as scientists to make an economic impact and to translate science into public benefit," Crawford said. "That's not a traditional way of thinking of universities, but at a certain point, we need to reassess that traditional thinking and take pride in the fact that a university's public contributions extends beyond its classrooms."

The paper points to the mission statement of the NIH, the nation's largest bioscience funding agency, which specifically includes a goal "to enhance the Nation's economic well-being and ensure a continued high return on the public investment in research."

"So as academic scientists, we are actually paid to protect and improve health, to prevent disease, and to enhance economic well-being," Crawford said. "This is not a sell-out to industry. It's an obligation to society."

Among the programs cited in the paper is a year-old mentoring program known as QB3 Startup in a Box, which connects scientists with external legal, professional and business experts to guide them in starting a new company. So far, the program has helped launch more than 75 virtual companies that are currently applying for grants, establishing business plans and pitching to investors. Seventeen are already operational.

Crawford emphasized that the goal of the analysis is not to assess blame, but to find solutions, and there are many. The authors also hope to generate discussion about which solutions work. The paper can be found online at www.sciencetranslationalmedicine.org.


'/>"/>

Contact: Kristen Bole
derek.deike@gmail.com
415-502-6397
University of California - San Francisco
Source:Eurekalert

Related biology news :

1. Should we play hide-and-go-seek with our childrens vegetables?
2. Reproductive health providers should discuss environmental exposure risks with patients
3. President, CEO Leppävuori, VTT: Finland should create a national bioeconomy strategy
4. Countries should implement inclusive wealth accounting
5. Happy Fathers Day! Another reason why dads and hopeful dads should quit smoking now
6. Should high-dose interleukin-2 continue to be the treatment of choice for metastatic melanoma?
7. Environmental groups should pool efforts to reach the public
8. Prenatal whole genome sequencing: Just because we can, should we?
9. Ecologist: Genetically engineered algae for biofuel pose potential risks that should be studied
10. Scientists conclude high fructose corn syrup should not be blamed for obesity
11. Scientists find that neurological changes can happen due to social status
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2016)... -- As part of its longstanding mission to improve genetic literacy ... released its latest children,s book, titled The One ... topics of inheritance and variation of traits that are part ... school classrooms in the US. The book ... Killoran , whose previous book with 23andMe, You ...
(Date:12/20/2016)... 2016 The rising popularity of mobility ... is stoking significant interest in keyless access systems. ... low energy (BLE), biometrics and near-field communication (NFC) ... of wireless technologies in the automotive industry. This ... access systems opens the market to specialist companies ...
(Date:12/19/2016)... BARCELONA , España y TORONTO , 19 ... fusión con Northern Biologics Inc. que permitirá el desarrollo acelerado de ... ensayos clínicos en varios tipos de tumor en 2017, con múltiples ... ... de su clase con objetivo en el factor inhibidor de leucemia ...
Breaking Biology News(10 mins):
(Date:1/24/2017)... New York, NY (PRWEB) , ... January 24, ... ... index (BMI), larger waist circumference, and increased serum leptin levels had a positive ... study. The study published in the International Neurourology Journal involved ...
(Date:1/24/2017)... ... 24, 2017 , ... Nor-Tech’s leading-edge demo cluster is proving ... Intel KNL. , Currently Cal Tech researchers are testing their code on ... cluster is a no-cost, no-strings opportunity for current and prospective clients to test-drive ...
(Date:1/24/2017)... ... January 23, 2017 , ... Edward Buckler, Ph.D., a research ... National Academy of Sciences Prize in Food and Agriculture Sciences. He is being ... National Academy of Sciences (NAS) Prize in Food and Agriculture Sciences was established ...
(Date:1/24/2017)... According to a new market ... Cell-based (CD34, PBMC, BLT)), Application (Neuroscience, Hematopoiesis, Oncology, Immunology ... Companies, CRO) - Global Forecast to 2021", published by ... Market for the forecast period of 2016 to 2021. ... by 2021 from USD 73.3 Million in 2016, growing ...
Breaking Biology Technology: