Navigation Links
Abuse during childhood linked to uterine fibroids in African-American women
Date:1/24/2013

(Boston) According to a new study from the Slone Epidemiology Center (SEC) at Boston University, African-American women who reported sexual or physical abuse before age 11 had a greater risk of uterine fibroids in adulthood compared with women who had no such abuse history. The association was strongest for women who experienced sexual abuse.

The study, which is published online in the American Journal of Obstetrics and Gynecology, was led by Lauren A. Wise, ScD, senior epidemiologist at SEC and associate professor of epidemiology at the Boston University School of Public Health.

This study followed 9,910 premenopausal African-American women from the Black Women's Health Study. In 2005, participants provided information on lifetime experiences of physical and sexual abuse during childhood (up to age 11), adolescence (ages 12-18), and adulthood (19 and older). The incidence of fibroids was ascertained from 2005 through 2011.

The results indicate that the incidence of uterine fibroids was increased by 16 percent among women who had been physically abused during childhood and by 34 percent among women who had been sexually abused during childhood. The risk of fibroids increased with increasing severity of child abuse. The results were weaker among women who reported high levels of coping, which is consistent with previous research showing that emotional support may buffer the negative health effects of violence. There was also little indication that abuse during adolescence and adulthood increased the risk of fibroids.

"This is the second prospective study to show an association between childhood abuse and uterine fibroids diagnosed during adulthood," said Wise. She noted that mechanisms might involve the influence of psychosocial stress on the biosynthesis or metabolism of sex steroid hormones, which are thought to be involved in fibroid development and growth. In addition, child sexual abuse is associated with sexually transmitted infections, which may also increase fibroid risk.

The lifetime risk of clinically-relevant uterine fibroids is 30 percent and they are a major contributor to gynecologic morbidity, including heavy menstrual bleeding, pelvic pain and infertility. In the U.S., fibroids account for more than $9.4 billion in health care costs annually and black women are two to three times more likely to be affected by the condition.

"Given the high prevalence of fibroids in African-American women, the association is of public health importance," Wise added.


'/>"/>
Contact: Jenny Eriksen Leary
jenny.eriksen@bmc.org
617-638-6841
Boston University Medical Center
Source:Eurekalert

Related biology news :

1. Scientists find gene interactions that make cocaine abuse death 8 times more likely
2. Abuse during childhood linked to adult-onset asthma in African-American women
3. Addictive properties of drug abuse may hold key to an HIV cure
4. RI Hospital: Use of PMP may increase demand for drug treatment, reduce painkiller abuse
5. BUSM researchers find link between childhood abuse and age at menarche
6. Increasing clarity for medics in suspected physical abuse cases
7. Choline supplementation during pregnancy presents a new approach to schizophrenia prevention
8. Chromosome anchors organize DNA during cell division
9. Music with dinner: Whales sing during foraging season, not just while breeding
10. Insight into DNA reprogramming during egg and sperm cell development
11. OHSU study shows that a molecule critical to nerve cells increases drammatically during hypertension
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/6/2017)... LONDON , April 6, 2017 ... Control, RFID, ANPR, Document Readers, by End-Use (Transportation & ... Energy Facility, Oil, Gas & Fossil Generation Facility, Nuclear ... Healthcare, Educational, Other) Are you looking for ... Authentication sector? ...
(Date:4/5/2017)... , April 4, 2017 KEY FINDINGS ... anticipated to expand at a CAGR of 25.76% during ... diseases is the primary factor for the growth of ... report: https://www.reportbuyer.com/product/4807905/ MARKET INSIGHTS The global ... product, technology, application, and geography. The stem cell market ...
(Date:3/30/2017)... March 30, 2017  On April 6-7, 2017, Sequencing.com ... Genome hackathon at Microsoft,s headquarters in ... will focus on developing health and wellness apps that ... Hack the Genome is the first hackathon for ... world,s largest companies in the genomics, tech and health ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... Florida (PRWEB) , ... October 11, 2017 , ... ... Drug Administration (FDA) has granted orphan drug designation to SBT-100, its novel anti-STAT3 ... for the treatment of osteosarcoma. SBT-100 is able to cross the cell membrane ...
(Date:10/10/2017)... Poway, California (PRWEB) , ... October 10, 2017 , ... ... afternoon speaking at his local San Diego Rotary Club. The event ... San Diego, CA and had 300+ attendees. Dr. Harman, DVM, MPVM was joined ...
(Date:10/10/2017)... ... 2017 , ... The Pittcon Program Committee is pleased to ... who have made outstanding contributions to analytical chemistry and applied spectroscopy. Each award ... conference and exposition for laboratory science, which will be held February 26-March 1, ...
(Date:10/9/2017)... ... October 09, 2017 , ... The Giving Tree Wellness Center ... the needs of consumers who are incorporating medical marijuana into their wellness and ... , As operators of two successful Valley dispensaries, The Giving Tree’s two founders, ...
Breaking Biology Technology: