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ASU receives prestigious $6.25 million multi-disciplinary research award from Department of Defense
Date:7/2/2012

e Department of Chemistry and Biochemistry. "He and his group members have produced a rapid and constant stream of innovative ideas and patents, an extreme rate of first-rate publications, an impressive portfolio of new approaches to teaching and training and an astounding rate of winning research funding, He is the embodiment of what ASU is doing as it reimagines and redefines its role in modern society. He has become one of the foremost academic leaders of his field."

Yan's research approach uses nature---in this case, DNA, the essential building block of all life on Earth---as the architectural underpinnings of a biomimicry approach to advance nanotechnology and ultimately build nano-scale devices.

"I am always very interested in designer architecture," said Yan. "Every architect needs a set of design rules. In the past, we have developed a variety of novel or unique strategies to design arbitrarily-shaped 2-D and 3-D structures by pursuing applications of DNA nanotechnology and attaching nanoparticles, enzymes, and proteins to make them more functional."

Yan will lead an elite team of researchers to increase their understanding of the design rules of constructing 3-D artificial enzyme centers and ultimately build nano-scale devices that mimic important biological systems, such as important biochemical pathways implicated in diseases or energy conversion during photosynthesis. The research team draws on expertise across several scientific fields and includes fellow ASU co-investigators Neal Woodbury and Don Seo; Mark Bathe, of the Massachusetts Institute of Technology; William Shih, Harvard Medical School; and Nils Walter, University of Michigan.

"There are so many biochemical pathways available in nature, and nature is so complicated," said Yan. "There are two main aspects of biochemical pathways: One is to convert mass, The other is to convert energy. We just want to grab some of the content and simplify it, and make it use
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Contact: Joe Caspermeyer
joseph.caspermeyer@asu.edu
480-727-0369
Arizona State University
Source:Eurekalert

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