Navigation Links
AMP commends SACGHS whole genome sequencing focus, raises ethical questions and forms working group
Date:6/16/2010

WASHINGTON, DC (June 15, 2010) Today, the Association for Molecular Pathology (AMP) presented public comments to the Secretary's Advisory Committee on Genetics, Health and Society (SACHGS) meeting focused on whole genome sequencing. In anticipation of advances in sequencing and its incorporation into clinical practice, AMP raised ethical and laboratory practice concerns for the Committee's consideration.

"In the next five years, the application of whole genome sequencing techniques in the lab and subsequently the clinic is a very real possibility," said Dr. Karen Mann, President of AMP. "There is a coming shift from using targeted molecular tests to using whole genome sequencing techniques and AMP commends the Committee for focusing its attention on the many challenges to the adoption of whole genome sequencing into clinical care."

As the technology advances, AMP's concerns focus on the clinical applications of whole genome sequencing. The advent or adoption of the technology itself is not controversial, but how clinical laboratories apply the technology and physicians utilize the information to inform clinical decision-making can generate many ethical challenges and laboratory practice questions.

AMP believes that the cornerstone of integrating this technology into laboratory practice will be the assessment of its clinical utility. Dr. Mann posed the question, "How can three billion base pairs of sequence and identification of the sequence of ~20,000 genes be coupled to clinical utility?" She added that "it will be difficult for molecular pathologists to associate meaning with the data generated by these tests and define a normal genome." AMP further believes that determining normal variation will be a major challenge when interpreting sequence results from tumor samples.

In its comments, AMP highlighted the following challenges and encouraged SACGHS to discuss these areas of concern:

  • Clin
    '/>"/>

Contact: Mary Steele Williams
mwilliams@amp.org
301-634-7921
Association for Molecular Pathology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. IEEE-USA commends president for asking Congress to double support for critical research
2. Expert recommends town councils to design low-allergy impact green spaces
3. APS commends President Obamas memorandum on scientific integrity
4. Research recommends compromise when choosing conservation site
5. Science Coalition commends Presidents strategy for innovation
6. Study recommends better handling of milk in restaurants
7. Health Physics Society recommends considering action for indoor radon below current guidelines
8. IOM report recommends framework to evaluate science behind health claims for foods and drugs
9. International panel recommends redirecting the world community toward sustainable growth
10. Intravenous gene therapy protects normal tissue of mice during whole-body radiation
11. Big Mac: The whole world on your plate
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/15/2014)... 2014 NXT-ID, Inc. (NASDAQ: NXTD and ... the growing mobile commerce market releases photos and video of the ... Monday October 13 th . Gino Pereira ... and angel investor Mr. Chad A. Verdi rang the ... thanked his investors and employees "for their work and dedication in ...
(Date:10/14/2014)... of years since T. rex took its ... scientists is breathing life back into dinosaurs using high-powered ... research has important implications for how dinosaurs used their ... sense of smell and cool their brains. , ... student Jason Bourke, lead author of the new study ...
(Date:10/14/2014)... – Scientists from The Scripps Research Institute (TSRI) have ... Health (NIH) to lead an investigation of Lassa fever ... Africa. The study aims to understand how Lassa fever ... others survive the inflection. , "The ultimate goal ... how Lassa fever virus causes disease and develop new ...
Breaking Biology News(10 mins):Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 3Dinosaur breathing study shows that noses enhanced smelling and cooled brain 2Dinosaur breathing study shows that noses enhanced smelling and cooled brain 3Scripps Research Institute team receives $6.6 million to investigate deadly Lassa virus 2
... the first-ever study to assess the social impact of ... that approximately 35 percent of children with food allergies, ... to have experienced bullying, teasing, or harassment as a ... experiencing teasing or harassment, 86 percent were reported to ...
... chevron formation or cyclists learned the value of drafting, fungi ... so as to spread them as high and as far ... , spews thousands of spores nearly simultaneously to form a ... a wind that carries many of the spores 20 times ...
... that plasmonic nanobubbles, generated around gold nanoparticles with a ... vivo by creating tiny, shiny vapor bubbles that reveal ... in the October print edition of the journal ... on zebra fish implanted with live human prostate cancer ...
Cached Biology News:First study of its kind finds children with food allergies are often victims of bullying 2Fungal spores travel farther by surfing their own wind 2Fungal spores travel farther by surfing their own wind 3Fungal spores travel farther by surfing their own wind 4'Gold' fish thrive, cancers die 2'Gold' fish thrive, cancers die 3
(Date:10/19/2014)... The report "Unmanned Ground Vehicle Market ... Payload, Type & by Geography - Forecasts & ... ground vehicle market into various sub segments with ... The report also identifies the factors driving this ... with the adoption trends. , The unmanned ground ...
(Date:10/18/2014)... October 18, 2014 The Asian arthroscopic ... Asia with analysis and forecast of revenue. The arthroscopic ... $712.3 million by 2018, at a CAGR of 6.5% ... of the Asian arthroscopic devices market, to get an ... a glimpse of the segmentation of arthroscopic devices market ...
(Date:10/18/2014)... October 18, 2014 According to a ... & Well Type - Global Trends & Forecasts up ... $31 billion in 2011. This value is expected to ... by 2017, with 10% CAGR during the same period. ... fracturing production market in terms of hydraulic horse power ...
(Date:10/17/2014)... SAN DIEGO and HILDEN, ...   , Translational research ... new capabilities being presented at the American Society ... Volume of 250,000-plus DNA samples linked to Ingenuity ... superior depth for genomic analysis  Ingenuity ...
Breaking Biology Technology:Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 2Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 3Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 4Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 5The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 2The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 3The Asian arthroscopic devices market is estimated to grow to $712.3 million by 2018 - New Report by MicroMarket Monitor 4Hydraulic Fracturing Market Projected To Reach $64 Billion by 2017 - New Report by MarketsandMarkets 2Hydraulic Fracturing Market Projected To Reach $64 Billion by 2017 - New Report by MarketsandMarkets 3Hydraulic Fracturing Market Projected To Reach $64 Billion by 2017 - New Report by MarketsandMarkets 4QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 2QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 3QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 4QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 5QIAGEN Demonstrates Expanded Bioinformatics Workflows at ASHG; Strong Market Adoption as Researchers Analyze Genomic Data on More Than a Quarter-Million Samples in Secure Private Cloud 6
... (2004) Synaptotagmin V and IX isoforms control , ... Sci 117:3119-3127. , ... , Journal of Cell Science, Iezzi and ... and the p Silencer 1.0-U6 vector in , ...
... Byrom, Vince , Pallotta, David Brown*, and Lance Ford* ... Austin, TX 78744-1832 * Corresponding authors <A , ... , , ... Labeling GAPDH and c-myc siRNA with either fluorescein , ...
... GLOBINclear-Human Globin mRNA Removal Kit , , ... from blood total RNA with a simple magnetic bead procedure (no , ... Increases sensitivity of gene , ... , Integrates ...
Cached Biology Technology:Your Data: Use of pSilencer 1.0-U6 siRNA Expression Vector in the Analysis of Synaptotagmin Location and Function 2Your Data: Use of pSilencer 1.0-U6 siRNA Expression Vector in the Analysis of Synaptotagmin Location and Function 3Your Data: Use of pSilencer 1.0-U6 siRNA Expression Vector in the Analysis of Synaptotagmin Location and Function 4Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 2Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 3Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 4Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 5Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 6Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 7Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 8Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 9Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 10Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 11Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 12Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 13Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 14Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 15Visualizing siRNA in Mammalian Cells: Fluorescence Analysis of the RNAi Effect 16Unmask Blood RNA for Gene Expression Profiling 2Unmask Blood RNA for Gene Expression Profiling 3Unmask Blood RNA for Gene Expression Profiling 4
Certified U.S. origin. Bovine Serum:, *Certified U.S. origin. Available raw, nonsterile filtered, or sterile filtered. , , *Sterility tested , , *Low Hemoglobin levels , , *Mycoplasma testing upon...
...
12(S)-HETE-d8 is used as an internal standard for the quantification of 12(S)-HETE by stable isotope dilution mass spectrometry....
Full-length cDNA 5-PRIME end of clone CS0DE013YM09 of Placenta of Homo sapiens (human). [Source:Uniprot/SPTREMBL;Acc:Q86TS7] Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
Biology Products: