Navigation Links
ACRG and BGI report new evidence for the genetic bases of liver cancer
Date:7/1/2013

r targeted therapies. Our findings in this study provide a better understanding of molecular basis of hepatocarcinogenesis and provide new clues to improving the diagnosis and treatment of liver cancer in the future."

"We detected a series of genes and pathways implicated in HBV-associated HCC using whole genome sequencing, which contribute to a better understanding of the tumor biology and targeted drug screening," said Dr. James Hardwick, Vice President of ACRG, and Director of Informatics & Analysis at Merck, "The ACRG was established to fuel research directed towards improving our understanding of cancers affecting Asian populations. By working together, we are able to generate important breakthroughs that can be transformed to better fight against liver cancer in the future."

"As clinicians, we are very excited about the several prevalent and actionable mutations identified from the study, including activating mutations of JAK1, which warrant testing several existing inhibitors for the treatment of the disease preclinically and clinically," said Dr. Ronnie Poon, Chair Professor and Chief, Division of Hepatobiliary and Pancreatic Surgery, The University of Hong Kong.


'/>"/>

Contact: Jia Liu
liujia@genomics.cn
BGI Shenzhen
Source:Eurekalert

Page: 1 2

Related biology news :

1. APS issues new policy requiring identification of sex or gender in reporting scientific research
2. Report presents designs for study of cancer risks near US nuclear facilities
3. Researchers report potential for a moderate New England red tide in 2012
4. Aware, Inc. Reports First Quarter 2012 Financial Results
5. Radiologists study necessity of additional imaging recommendations in PET/CT oncologic reports
6. BGI reports the completed sequence of foxtail millet genome
7. Science reporters win ASM Public Communications Award
8. ACRG and BGI report findings from genomics research on recurrent hepatitis B virus integration
9. iView Systems iTrak® version 5.5 delivers optimized Incident Reporting
10. Report details efforts to improve, advance indoor microbial sampling
11. New report examines effects of trees killed by bark beetles on wildfire
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2014)... Some infants born with neonatal abstinence syndrome (NAS) ... difficult time going through withdrawal than others, but ... genetic and epigenetic (when genes are turned on ... potential factors, researchers at Boston University School of ... a first of its kind study to identify ...
(Date:8/19/2014)... Center at San Antonio and The University of Texas ... more than $750,000 in grants through the San Antonio ... 2003, SALSI is a model of how a general ... join forces for greater research and graduate education. , ... on public health issues and diseases of global impact. ...
(Date:8/19/2014)... 2014A new ovoid structure discovered in the Nakhla Martian ... variety of minerals, and shows evidence of undergoing a ... the permafrost and mixing of surface and subsurface fluids. ... analytical studies to determine the origin of this new ... ovoid formed, point to the most likely conclusion, and ...
Breaking Biology News(10 mins):In-utero methadone, Subutex exposure could alter gene expression, cause severe Neonatal Abstience Syndrome 2San Antonio Life Sciences Institute awards $750,000 to innovators 2San Antonio Life Sciences Institute awards $750,000 to innovators 3Life on Mars? Implications of a newly discovered mineral-rich structure 2
... the ends of bones where they meet in a ... can lead to degenerative disease. Treatments and experimental approaches ... but currently there is no method to fully restore ... delivery of therapeutic proteins to the injured site is ...
... of good advice to help us avoid becoming obese, such ... surprising piece of advice based on a promising area of ... that certain viruses may cause obesity, in essence making obesity ... a new study, "Adipogenic potential of multiple human adenoviruses in ...
... depression-like social withdrawal syndrome, repeated defeat by dominant animals ... its brain that could help to explain why depression ... the National Institutes of Health's (NIH) National Institute of ... this animal model of depression, silencer molecules turned off ...
Cached Biology News:Stem cells from muscles can repair cartilage 2Stem cells from muscles can repair cartilage 3Contagious obesity? Identifying the human adenoviruses that may make us fat 2Contagious obesity? Identifying the human adenoviruses that may make us fat 3Contagious obesity? Identifying the human adenoviruses that may make us fat 4Depression model leaves mice with molecular scar 2
(Date:8/20/2014)... Bulgaria (PRWEB) August 20, 2014 ... was released today including improvements to the enterprise ... and connectors for Lucene, SOLR and Elasticsearch. This ... for this high performance triplestore – GraphDB™ was ... interested in deploying the only mature enterprise resilient ...
(Date:8/19/2014)... Columbia, Md. (PRWEB) August 19, 2014 ... integrated liquid chromatography systems, Prominence-i and Nexera-i, adding ... UHPLC systems. Combining excellent functionality, an intuitive operating ... performance and a more efficient workflow for conventional ... systems feature innovative, intuitive and intelligent design so ...
(Date:8/19/2014)... DANVILLE, Pa. , Aug. 19, 2014 ... C has been nominated for a Centers for Disease ... to addressing a major public health concern. ... Health System, is one of a team of researchers ... (CDC) Charles C. Shepard Science Award for Data Methods ...
(Date:8/19/2014)... 19, 2014 Research and Markets  has announced ... - Global Strategic Business Report" report to their offering. ... Solid Oxide Fuel Cells (SOFCs) in US$ Thousands. The report ... , Europe , Asia-Pacific ... are provided for the period 2012 through 2020. Market data ...
Breaking Biology Technology:Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 2Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 3Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 4Shimadzu’s New i-Series Integrated Liquid Chromatography Systems Provide Laboratories Wider Range of Analytical Capabilities 2Shimadzu’s New i-Series Integrated Liquid Chromatography Systems Provide Laboratories Wider Range of Analytical Capabilities 3Geisinger investigator nominated for federal award 2Geisinger investigator nominated for federal award 3Global Solid Oxide Fuel Cells (SOFCs) - Strategic Business Report 2014 2
... a new generation of piezoelectric nanogenerators with two types ... to be the first self-powered nanometer-scale sensing devices that ... The new devices can measure the pH of liquids ... current produced from mechanical energy in the environment. ...
... FRANCISCOScientists at Carnegie Mellon University,s Department of Chemistry and ... state-of-the-art in live cell fluorescent imaging by developing a ... from violet to the near-infrared. The new technology, ... of individual proteins in living cells in real time. ...
... ... of Business Award in the Commercial Site category by the Small Business Commerce Association (SBCA). ... identified through statistical research and monthly surveys. , ... Emeryville, CA (PRWEB) March 25, 2010 -- BioSoteria, Inc ., a ...
Cached Biology Technology:Researchers use improved nanogenerators to power sensors based on zinc oxide nanowires 2Researchers use improved nanogenerators to power sensors based on zinc oxide nanowires 3Carnegie Mellon scientists create rainbow of fluorescent probes 2Drug Safety Firm BioSoteria Receives 2009 Best of Business Award 2
... Early Drug Development with Imaging Mass Spectrometry ... compound localization data in early drug development ... spectrometry service maps unlabeled ions ... you can localize drugs and metabolites prior ...
... The AccuSpot automates LC micro-fractionation, ... With the AccuSpot system, LC eluent ... onto target plates, in trace amounts. ... target plates for MALDI-TOF-MS measurements. When ...
... The JNK (c-Jun NH2-terminal kinase) ... three identified MAP kinase pathways in ... response to environmental stress, is associated ... itself, and is implicated in the ...
... knockdown of all human, mouse, and ... Genomewide, predesigned siRNAs for a ... , Ready-to-use, convenient matching solutions for ... Cost-effective RNAi and downstream analysis ...
Biology Products: