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AAOS awards recognize innovative orthopaedic research
Date:3/19/2013

CHICAGO The Kappa Delta Sorority and the Orthopaedic Research and Education Foundation (OREF) presented four research awards to scientists who are helping to close the gap between basic research and patient treatment and care. Honored at the 2013 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS), these award winners have made recent discoveries in the following areas of musculoskeletal health:

  • Bio-enhanced ACL repair
  • The diagnosis and treatment of posterolateral (outside and back) corner knee injury
  • Skeletal muscle design and the implications for orthopaedic surgery
  • The role of mechanical factors in bone healing

The Biology of ACL Injury and Repair

The 2013 Kappa Delta Ann Doner Vaughn Award was presented to Martha M. Murray, MD, of Boston Children's Hospital, for the study, "The Biology of ACL Injury and Repair."

The paper outlines 25 years of research and discovery leading to the novel development of a "bio-enhanced" ACL repair procedure that "stimulates healing and regeneration of the ACL" and minimizes future injury-related osteoarthritis in preclinical models, said Dr. Murray.

First, Dr. Murray's team determined that the premature loss of the provisional scaffold (scar tissue) surrounding the ACL prevents healing. That discovery led them to develop and test various methods to stimulate the healing of these tissues within the ACL wound site. Most promising was the creation and successful implant of a substitute, provisional scaffold that restored functional healing in animal tests. The procedure is far less invasive than current ACL repair surgery.

"This less invasive method has shown promise in preclinical models, where the strength of the repaired ACL is similar to that of an ACL reconstruction at 3 months, 6 months and 1 year," said Dr. Murray. "In addition, the premature osteoarthritis seen in the reconstructed knees was not seen in the knee
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Contact: Lauren Pearson Riley
pearson@aaos.org
708-227-1773
American Academy of Orthopaedic Surgeons
Source:Eurekalert

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