Navigation Links
AACR names Perou 2009 Outstanding Investigator for Breast Cancer Research

CHAPEL HILL, NC Calling his work "one of the most important findings in breast cancer and health disparities in the last decade," the American Association for Cancer Research (AACR) has named Charles M. Perou, Ph.D. the 2009 Outstanding Investigator Award for Breast Cancer Research, funded by Susan G. Komen for the Cure.

Perou, who is an associate professor of genetics, pathology & laboratory medicine, and a member of UNC Lineberger Comprehensive Cancer Center, will present an invited lecture this week at the 32nd Annual San Antonio Breast Cancer Symposium and receive an honorarium.

Perou's work sets the stage to redefine breast cancer into multiple subtypes of disease. His findings are causing the entire field to reevaluate all preconceived notions regarding what causes breast cancer and how to treat it. Recognition of his accomplishments by AACR and Komen demonstrate the power of his ideas and their rapid acceptance by the scientific and clinical communities.

Perou's research crosses the disciplines of biology, genetics, bioinformatics, epidemiology and the clinical treatment of breast cancer. His major contribution to the field has been leading a team that has characterized the diversity of breast tumors and classified them in a way that helps physicians better understand why some cancers do not respond to standard therapies and to tailor treatment to the patient's disease type.

He and his colleagues have demonstrated that breast tumors can be classified into five molecular subtypes, with his lab focusing particular attention on the basal-like tumor subtype, which has a poor prognosis when given standard therapy. He is also currently studying the mechanisms that give rise to each tumor subtype, why some subtypes respond to chemotherapy and others do not, and he is using animal models and human clinical trials samples to develop new therapies targeted to each of the different subtypes.

With UNC Lineberger members Dr. Bob Millikan, who is the Barbara Sorenson Hulka Distinguished Professor of Epidemiology in the Gillings School of Global Public Health, and Dr. Lisa Carey, associate professor of hematology/oncology and director of the UNC Breast Center, Perou has translated these molecular subtypes to the wider patient population. Using a North Carolina-based study of a population-representative breast cancer patient set, this team found that pre-menopausal African American women are diagnosed with one particular subtype, the basal-like tumor, twice as often as their Caucasian counterparts providing significant insight into racial disparities that have long been known to exist in breast cancer mortality. Ongoing work is demonstrating that each breast cancer subtype has distinct risk factors.

In presenting the award, AACR notes that Perou's laboratory discoveries are being incorporated into clinical practice the treatment of patients worldwide. The organization also cites his international leadership in bioinformatics analysis of gene expression data and notes that these techniques will help researchers better compare animal models of cancer with those in humans, potentially speeding up preclinical trials of new therapeutic agents.


Contact: Ellen de Graffenreid
University of North Carolina School of Medicine

Related biology news :

1. Entomological Society of America names 2009 award winners
2. Biophysical Society names 2010 award recipients
3. Entomological Society of America names 2009 Fellows
4. Technology Review names Carnegie Mellons Treuille as a top young innovator
5. Impact Factor names Cell top research journal
6. UC Riverside researcher names lichen after President Barack Obama
7. AIBS names 2009 emerging public policy leaders
8. Names turn preschoolers into vegetable lovers
9. WCC Smart Search & Match Names Tarvinder Sembhi as VP Sales for the ID Market
10. WCC Smart Search and Match Names Rudie Lion - Product Marketing Manager
11. WCC Smart Search and Match Names Rudie Lion - Product Marketing Manager
Post Your Comments:
Related Image:
AACR names Perou 2009 Outstanding Investigator for Breast Cancer Research
(Date:6/20/2016)... -- Securus Technologies, a leading provider of civil ... investigation, corrections and monitoring announced that after exhaustive ... the final acceptance by all three (3) Department ... (MAS) installed. Furthermore, Securus will have contracts for ... October, 2016. MAS distinguishes between legitimate wireless device ...
(Date:6/7/2016)...  Syngrafii Inc. and San Antonio Credit Union ... integrating Syngrafii,s patented LongPen™ eSignature "Wet" solution into ... result in greater convenience for SACU members and ... existing document workflow and compliance requirements. ... Highlights: ...
(Date:6/1/2016)... 2016 Favorable Government Initiatives Coupled ... Criminal Identification to Boost Global Biometrics System Market Through ... Research report, " Global Biometrics Market By Type, ... Opportunities, 2011 - 2021", the global biometrics market is ... account of growing security concerns across various end use ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... ... June 27, 2016 , ... Parallel 6 , the leading software ... Clinical Reach Virtual Patient Encounter CONSULT module which enables both audio and ... clinical trial team. , Using the CONSULT module, patients and physicians can schedule a ...
(Date:6/24/2016)... 2016  Regular discussions on a range of subjects including ... two entities said Poloz. Speaking at a lecture ... , he pointed to the country,s inflation target, which is ... "In certain areas there ... common economic goals, why not sit down and address strategy ...
(Date:6/23/2016)... Wausau, WI (PRWEB) , ... June 23, 2016 ... ... probiotic supplements, is pleased to announce the launch of their brand, UP4™ Probiotics, ... supplements for over 35 years, is proud to add Target to its list ...
(Date:6/23/2016)... Lawrence, MA (PRWEB) , ... June 23, 2016 ... ... the Peel Plate® YM (Yeast and Mold) microbial test has received AOAC Research ... test platform of microbial tests introduced last year,” stated Bob Salter, Vice President ...
Breaking Biology Technology: