Navigation Links
A worm-and-mouse tale: B cells deserve more respect
Date:2/26/2009

By studying how mice fight off infection by intestinal worms a condition that affects more than 1 billion people worldwide scientists have discovered that the immune system is more versatile than has long been thought. The work with worms is opening a new avenue of exploration in the search for treatments against autoimmune diseases like diabetes and asthma, where the body mistakenly attacks its own tissues.

The findings, reported by scientists who performed the work at the Trudeau Institute in Saranac Lake, N.Y., and who are now at the University of Rochester Medical Center, appear in the March issue of the journal Immunity. The article was published online Feb. 26.

The research focuses mainly on B cells, one of many types of immune cells that the body maintains to fight off invaders like bacteria, viruses, and parasites. Besides B cells, there are T cells, macrophages, neutrophils, monocytes, mast cells and others, all working in concert to keep an organism healthy. The cells cruise our bodies, looking to eliminate infectious threats before they become a serious risk to our health.

For many years, scientists believed that the major job of B cells was to identify foreign invaders and tag them with antibodies, marking the microbe for destruction by the immune system. But scientists are discovering that B cells do much more, resulting in new information about our immune system that could be useful for developing more effective vaccines and better treatments for many types of disease.

In the past few years, Frances Lund, Ph.D., professor of Medicine in the Division of Allergy/Immunology and Rheumatology at the University of Rochester Medical Center, has found an array of unexpected functions for B cells. In the laboratory, she has found that B cells produce chemical signaling molecules known as cytokines that spur other immune cells in the body to action. Her team has also shown that B cells are crucial for presenting
'/>"/>

Contact: Tom Rickey
tom_rickey@urmc.rochester.edu
585-275-7954
University of Rochester Medical Center
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. From stem cells to new organs: Stanford and NYU scientists cross threshold in regenerative medicine
2. UCLA stem cells scientists make electrically active motor neurons from iPS cells
3. Researchers generate functional neurons from somatic cells
4. Researcher seeks to turn stem cells into blood vessels
5. Cells with double vision
6. Singapore research organisations team up to advance drug discovery using brain tumor stem cells
7. CSHL researchers identify gene that helps plant cells keep communication channels open
8. Artificial cells, simple model for complex structure
9. Engineers create intelligent molecules that seek-and-destroy diseased cells
10. CSHL scientists discover how companion cells to sperm protect them from genetic damage
11. Dont go changing: New chemical keeps stem cells young
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... Women who are poor experience higher cortisol levels ... levels of the stress hormone, putting them at ... to a new research from the University of Colorado ... American Journal of Human Biology , is the ... directly to the socioeconomic status of their mothers during ...
(Date:8/20/2014)... 4,000 members, it triggers an important first stage in ... of comb used for rearing male reproductive, called drones. ... and Behaviour at Cornell University, led by Michael Smith, ... The results are published in Springer,s journal Naturwissenschaften ... isn,t always a honeybee colony,s top priority. Early ...
(Date:8/20/2014)... leaves, photosystem 1 (PS1) absorbs light and its ... carbon dioxide to biomass. Photovoltaic devices, mostly build ... but produce electricity. One approach for the development ... the semi-conductor with the isolated membrane protein complexes ... a highly stable PS1 from thermophilic cyanobacteria that ...
Breaking Biology News(10 mins):CU Denver researcher shows economic disparities impact infant health 2Worker bees 'know' when to invest in their reproductive future 2A semi-artificial leaf faster than 'natural' photosynthesis 2
... island of Madagascar harbors a unique biodiversity that evolved ... Numerous plant and animal species are found solely on ... most prominent representatives of the island,s unique fauna. They ... are two species of the genus Eulemur that also ...
... African Australians Inc Award at Parliament House on ... remarkable contributions to Australia, Africa and the world ... engagement by African Australians." Professor Hayes heads ... Institute of Medical Research, while also holding a ...
... New research findings from the Centre for Permafrost (CENPERM) ... University of Copenhagen, document that permafrost during thawing may ... the atmosphere and that the future water content in ... permafrost thawing. The findings may lead to more accurate ...
Cached Biology News:Scientists from Mainz and Antananarivo describe Lavasoa Dwarf Lemur as new primate species 2Professor Vanessa Hayes awarded for exceptional Africa-related work 2Professor Vanessa Hayes awarded for exceptional Africa-related work 3New knowledge about permafrost improving climate models 2
(Date:8/21/2014)... 2014 SoundConnect , a ... as one of the nation’s Fastest Growing Private ... the 2nd consecutive year. Inc. magazine today ranked ... 500|5000, an exclusive ranking of the nation's fastest-growing ... look at the most important segment of the ...
(Date:8/20/2014)... time, chemists have succeeded in measuring vibrational motion of ... study reveals how vibration of a single molecule differs ... The study was performed at the University of California, ... of Jyvskyl works as a visiting fellow under professor ... The second team was lead by Professor Eric O. ...
(Date:8/20/2014)... Francisco, CA (PRWEB) August 20, 2014 ... Conference is being held on October 29-30 in ... perspectives from industry, academic and government researchers and clinicians ... in the space. , In the twelve years ... one hundred therapies have been introduced with pharmacogenetic information ...
(Date:8/20/2014)... (PRWEB) August 20, 2014 ... released today including improvements to the enterprise replication ... connectors for Lucene, SOLR and Elasticsearch. This release ... this high performance triplestore – GraphDB™ was formerly ... in deploying the only mature enterprise resilient RDF ...
Breaking Biology Technology:SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 2SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 3Seeing a molecule breathe 26th Annual Personalized and Precision Medicine Conference Bringing Together Thought Leaders to Discuss Clinical Implementation, Dx Reimbursement, Big Data, and Sequencing 2Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 2Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 3Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 4
... The following was,released today by the Tech Council of ... that is paying off but,it must be safeguarded and ... other states seek 21st century,economic engines we Marylanders can ... drivers, the bioscience industry. This blossoming industry,has expanded over ...
... a New Generation of Drug Candidates ... for Inflammatory ... Germany,September 10 Cellzome Inc. and GlaxoSmithKline (LSE & NYSE:,GSK) ... and market novel kinase-targeted therapeutics to treat inflammatory,diseases., The ...
... that a research scientist and university professor gets to see his ... months, Richard W. Siegel will get to watch his name scroll ... new title that seems light years away from laboratory benches and ... has been a three-year labor of love for Siegel. From securing ...
Cached Biology Technology:Protect Maryland's Bioscience Industry 2Protect Maryland's Bioscience Industry 3GlaxoSmithKline and Cellzome Announce Major Strategic Alliance 2GlaxoSmithKline and Cellzome Announce Major Strategic Alliance 3GlaxoSmithKline and Cellzome Announce Major Strategic Alliance 4Professor-turned-producer learns the movie biz 2Professor-turned-producer learns the movie biz 3Professor-turned-producer learns the movie biz 4Professor-turned-producer learns the movie biz 5
... by R. Edwards (1996) • ... types of immunoassays, including RIA, ... and on the photoluminescent and ... information is also given on ...
ANTI S. ENTERID LPS...
B.D. Hames and D.M. Glover (1996) • This issue covers T-Cell antigen receptor genes; T-Lymphocyte signal transduction; B-Cell activation antibody engineering and the complement system and other ...
Request Info...
Biology Products: