Navigation Links
A unique arrangement for egg cell division
Date:8/13/2007

Heidelberg, 09 August 2007 - Which genes are passed on from mother to child is decided very early on during the maturation of the egg cell in the ovary. In a cell division process that is unique to egg cells, half of the chromosomes are eliminated from the egg before it is fertilised. Using a powerful microscope, researchers from the European Molecular Biology Laboratory (EMBL) have now revealed how the molecular machinery functions that is responsible for chromosome reduction of egg cells in mice. In the current issue of Cell they report the assembly of this machinery, which is very different from what happens in all other cells in the body. The process is likely conserved across species and the new insights might help shed light on defects occurring in human egg cell development.

The first step in the development of an egg cell is the division of its progenitor cell, the oocyte. Unlike other cells in the body, an oocyte does not divide equally to produce two identical daughter cells. Instead, it undergoes a reducing division, which halves its genetic material to generate a single egg cell with 23 instead of the normal 46 chromosomes in humans. It is crucial that the egg has half the normal set of chromosomes, because the second half is brought in by the sperm cell during fertilisation. The molecular apparatus that makes sure that the egg ends up with the correct number of chromosomes is a bipolar spindle consisting of protein filaments, called microtubules that are part of the cells skeleton. Spindle microtubules attach themselves to the chromosomes, separate them and pull one half out of the oocyte into a small polar body that is later discarded.

Microtubule spindles are found in all dividing cells. What is special about oocytes is that they lack specialised spindle-forming organelles, called centrosomes, says Jan Ellenberg, Coordinator of the Gene Expression Unit at EMBL, all other cells contain two centrosomes from where the microtubules originate.
'/>"/>

Contact: Lena Raditsch
lena.raditsch@embl.de
49-622-138-78125
European Molecular Biology Laboratory
Source:Eurekalert

Page: 1 2

Related biology news :

1. The transparent organism: EMBLEM and Carl Zeiss give labs a unique look at life
2. Scientists discover unique microbe in Californias largest lake
3. Breast Cancer May Be Uniquely Sensitive To Inhibitors Of PI3K Pathway
4. Unique library of plant genes germinates, takes root at UNC
5. Invitrogen Launches i-Path -- A Unique Systems Biology Platform at BIO 2005
6. Cultural norms not unique to human societies
7. Jumping genes contribute to the uniqueness of individual brains
8. New, unique microscope for nanotech
9. Computers to save unique type of American red squirrel
10. Uniquely human component of language found in gregarious birds
11. Immune system response to viral DNA is unique
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... 2014 Winners of The Economist,s prestigious Innovation ... to take place at the JW Marriott Hong Kong on Friday, ... will share their experiences and the lessons those hold for others. ... innovation over the past decade, will be presented at a ceremony ... summit. It will be the first time the ceremony has come ...
(Date:9/29/2014)... DC September 29, 2014 -- Plants have ... bacteria help the pants extract nutrients and defend ... pathogens from contaminating fruits and vegetables. Now, scientist ... bacteria inside of seeds; thus ensuring that sprouting ... from the University of Notre Dame, presented their ...
(Date:9/29/2014)... school? According to a new Food and Brand Lab ... can increase participation in the National School Lunch Program ... vegetables by 16%! , Chefs Move to Schools (CMTS), ... chefs with schools in order to provide nutrition instruction ... service workers. , A CMTS event was held in ...
Breaking Biology News(10 mins):Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 2Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 3Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 4Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 5Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 6Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 7Plants prepackage beneficial microbes in their seeds 2Chefs move to schools can increase school meal participation and vegetable intake among students 2
... may hold the answer to making solar cells a ... of Engineering Physics at McMaster University, Cleanfield Energy and ... partnership to pursue the commercialization of nanowire technology in ... of nanowire technology developed at McMaster is able to ...
... 2008) Determined to revive the grossly depleted soils ... of poverty and hunger, the Alliance for a Green ... five-year program to restore the fertility of Africas soils. ... into soils where rapid nutrient loss is sapping the ...
... at the Picower Institute for Learning and Memory at MIT ... they have created a way to see, for the first ... circuit in a living animal. This revolutionary method allowed ... to see how bypassing a major memory-forming circuit in the ...
Cached Biology News:Nanowires hold promise for more affordable solar cells 2Alliance for a Green Revolution in Africa commits 180M to revive farmers' depleted soils 2Alliance for a Green Revolution in Africa commits 180M to revive farmers' depleted soils 3Alliance for a Green Revolution in Africa commits 180M to revive farmers' depleted soils 4New MIT tool probes brain circuits 2
(Date:9/30/2014)... Sept. 30, 2014 Pacific Northwest Biotechnology, ... Summary Global Markets Direct,s, ,Pacific Northwest Biotechnology, ... an overview of the Pacific Northwest Biotechnology, LLC,s ... provides comprehensive information on the current therapeutic developmental ... comparative analysis at various stages, therapeutics assessment by ...
(Date:9/30/2014)... Sept. 30, 2014 Nematicide is a ... Nematodes are microscopic parasitic roundworms, found in massive ... other plants and animals. Nematicides have tended to ... properties promoting migration through the soil. A single ... plant-parasitic nematodes. With more than 10,000 species classified, ...
(Date:9/30/2014)... Follow us on LinkedIn –Cholesterol ... cholesterol carrier or lipoprotein in the blood. Such tests ... in the body, especially along the walls of blood ... other cardiovascular disorders. Cardiovascular Diseases (CVD) is the leading ... on a regular basis, to assess an individual’s risk ...
(Date:9/30/2014)... Hungary , September 30, 2014 ... and intuitive browsing of chemistry in documents ... chemistry software solutions and consulting services for life ... chemical information and generate Markush structures from documents. ... an organizations intellectual property, however generating and understanding ...
Breaking Biology Technology:Pacific Northwest Biotechnology, LLC - Product Pipeline Review - 2014 2Pacific Northwest Biotechnology, LLC - Product Pipeline Review - 2014 3Nematicides Market by Types (Fumigants, Organophosphates, Carbamate and Bio-Nematicides), Applications (Agrochemicals, Industrial, and Others), and Geography (North America, Europe, Asia-Pacific & ROW) - Global Trends & Forecasts to 2019 2Surging Diabetic, Obese and Hypertensive Population Drives the Global Cholesterol Testing Market, According to New Report by Global Industry Analysts, Inc. 2Surging Diabetic, Obese and Hypertensive Population Drives the Global Cholesterol Testing Market, According to New Report by Global Industry Analysts, Inc. 3Surging Diabetic, Obese and Hypertensive Population Drives the Global Cholesterol Testing Market, According to New Report by Global Industry Analysts, Inc. 4ChemAxon Introduces ChemCurator for Chemical Information Extraction and Markush Structure Creation 2
... Fiserv Inc. has unveiled a program of healthcare ... processing and health-plan administration. , ,Spurred on ... banking is a set of services which includes ... payments between parties in healthcare transactions. , ...
... The increased use of clinical technologies in healthcare does ... for care decisions, particularly when technology vendors include strong ... developers market their products more directly to consumers, they ... attendees of the recent Digital Healthcare Conference ...
... events, is coming to Milwaukee again on June 22 and 23 ... both global and Wisconsin-area technology companies. , ,The conference will feature ... Networks , Agilent , EqualLogic , Inacom , ... Runner Business Class and other companies. , ,Attendees will have ...
Cached Biology Technology:Liability issues not seen as roadblock to healthcare technology advancements 2Liability issues not seen as roadblock to healthcare technology advancements 3
... Normal;heading 1;heading 2;Many ... and experimental situations ... standard transfection and ... systems. ViraPower Lentiviral ...
Immunogen: Synthetic peptide: M(1) C V P R S G L I L S(11) Storage: -20 C, Avoid Freeze/Thaw Cycles...
... pPIC3.5K vectors carry the kanamycin resistance gene ... Pichia. Spontaneous generation of multiple insertion events ... levels of Geneticin Reagent. Pichia transformants are ... their level of resistance to Geneticin Reagent. ...
...
Biology Products: