Navigation Links
A tiny pinch from a 'z-ring' helps bacteria cells divide
Date:10/11/2007

In process that is shrouded in mystery, rod-shaped bacteria reproduce by splitting themselves in two. By applying advanced mathematics to laboratory data, a team led by Johns Hopkins researchers has solved a small but important part of this reproductive puzzle.

The findings apply to highly common rod-shaped bacteria such as E. coli, found in the human digestive tract. When these single-celled microbes set out to multiply, a signal from an unknown source causes a little-understood structure called a Z-ring to tighten like a rubber band around each bacteriums midsection. The Z-ring pinches the rod-like body into two microbial sausages that finally split apart. To shed light on this process, the Johns Hopkins-led team developed a mathematical tool that computed the mechanical force exerted by the Z-ring when it helps these cells split.

The calculation will aid scientists who are trying to learn more about how these microbes live and reproduce. The work also may hasten the development of a new type of antibiotic that could disable the Z-ring to keep harmful bacteria in check.

The bacteria research was reported in the Oct. 9 edition of Proceedings of the National Academy of Sciences. The work was led by Sean X. Sun, an assistant professor of mechanical engineering in Johns Hopkins Whiting School of Engineering.

This type of bacteria is commonly found in the human body, said Sun, a co-author of the journal article. Understanding how organisms like this work can help us find new ways to treat bacterial illnesses, develop medications or do any type of bioengineering involving bacteria. If you want to target certain cellular activities, you need to know how single-celled creatures like this operate.

Suns team brought a fresh perspective to the study of cell activity. While traditional biologists try to identify and learn the function of tiny of bits of genetic material within cells, Sun studies how such proteins work toge
'/>"/>

Contact: Phil Sneiderman
prs@jhu.edu
443-287-9900
Johns Hopkins University
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Jumping gene helps explain immune systems abilities
2. Protein helps regulate the genes of embryonic stem cells
3. Scientists reveal the shape of a protein that helps retroviruses break into cells
4. Thai spice helps cut blood sugar swings
5. Newly Discovered Branding Process Helps Immune System Cells Pick Their Fights
6. Chemists synthesize molecule that helps body battle cancers, malaria
7. Ancient DNA helps clarify the origins of two extinct New World horse species
8. Massey Cancer Center researcher helps to identify a piece of the cancer puzzle
9. Study: Well-known protein helps stem cells become secretory cells
10. Beyond genes: Lipid helps cell wall protein fold into proper shape
11. Simple sea sponge helps scientists understand tissue rejection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... that characterize sustainable university and college programs designed ... teachers. Specifically, one or more faculty members who ... with institutional motivation and commitment can ensure that ... Math (STEM) teacher shortages are especially acute in ... institutions seeking to increase the number of STEM ...
(Date:7/24/2014)... TORONTO, June 24, 2014 Some sticky research out ... fight against a certain species of toxic grass fungus: ... this month,s Biology Letters , "Ungulate saliva inhibits ... when applied to red fescue grass (which hosts a ... results in slower fungus growth and less toxicity. , ...
(Date:7/24/2014)... 24, 2014(BRONX, NY)Researchers at Albert Einstein College of ... from The Michael J. Fox Foundation for Parkinson,s Research ... for Parkinson,s disease. This drug discovery project will test ... goal of developing a drug that acts on an ... therapies for Parkinson,s help many people manage their symptoms, ...
Breaking Biology News(10 mins):Creating sustainable STEM teacher preparation programs 2Moose drool inhibits growth of toxic fungus: York U research 2Albert Einstein College of Medicine receives grant from the Michael J. Fox Foundation to fund drug discovery project targeting Parkinson's 2Albert Einstein College of Medicine receives grant from the Michael J. Fox Foundation to fund drug discovery project targeting Parkinson's 3
... While there is no cure for lingering viral infections ... Princeton University suggests it may be possible to deactivate ... switch. , Princeton scientists Leor Weinberger and Thomas ... which human immunodeficiency virus (HIV) and other viruses transition ...
... have found a new pathway by which cells change their ... Institutes of Health, they plan to fill in the details ... could lead to a better understanding of the importance of ... Cells must interact with each other to produce system responses, ...
... University Massey Cancer Center today presented preclinical research ... meeting suggesting the potential of a new combination ... , In this study, led by Steven Grant, ... between bortezomib and romidepsin (Gloucester Pharmaceuticals) and bortezomib ...
Cached Biology News:Scientists find potential 'off-switch' for HIV virus 2Scientists find potential 'off-switch' for HIV virus 3Scientists find potential 'off-switch' for HIV virus 4New molecular pathway could reveal how cells stick together 2
(Date:7/24/2014)... Gain recognition for leadership and contribution ... biotech industry. Nominations are now being accepted for ... by the Bio Supply Management Alliance , ... professionals for the past 7 years. , Awards ... industry – Manufacturers, Service Providers, Material Suppliers, Technology ...
(Date:7/24/2014)... Security forces worldwide rely on sophisticated equipment, trained ... other public areas against terrorist attacks. A revolutionary ... about to make their job much easier. , ... Patolsky of Tel Aviv University ,s School of ... developed by the Herzliya company Tracense, picks up ...
(Date:7/24/2014)... Although most natural and synthetic processes prefer to ... potential or energyit is within the realm of ... experience constant changes in energy and phases, such ... These conditions allow humans to regulate their body ... rumble with seismic activity. , But even ...
(Date:7/24/2014)... July 24, 2014 SRI International has been ... National Institute of Allergy and Infectious Diseases (NIAID), part ... development of potential therapies for HIV infection and AIDS. ... HIV and AIDS and the complications and opportunistic infections ... preventing sexual transmission of HIV. According ...
Breaking Biology Technology:Call for Submission: BSMA’s Supply Chain Management Innovation Awards 2Call for Submission: BSMA’s Supply Chain Management Innovation Awards 3Nano-sized chip 'sniffs out' explosives far better than trained dogs 2New approach to form non-equilibrium structures 2National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 2National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 3
... across the developing world could reduce the environmental impact ... India, writing today in the Inderscience publication, International Journal ... in the developing world are encouraged to compost our ... compost bin and not all of us are willing ...
... sustainable solar energy by imitating nature. Nanotechnology researchers like ... nanoscale materials that mimic the architecture of grass and ... , A new podcast looks at how Dr. Lewis ... tiny nanoparticles into simple, inexpensive everyday products like house ...
... Lee Biosolutions, Inc, (http://www.leebio.com ) announces the ... human renin from human kidney. Human Renin ... blood pressure,and electrolyte homeostasis and therefore is of ... renin are of importance for the,development of hypertension ...
Cached Biology Technology:Landfill mining reduces environmental impact of growing waste 2
Human peripheral blood basophils, For immunohistochemistry (IHC) Cell Chip with Human Peripheral Blood Granulocytes...
Human peripheral blood neutrophils, For immunohistochemistry (IHC) Cell Chip with Human Peripheral Blood Granulocytes...
Human peripheral blood CD56+ NK cells, For immunohistochemistry (IHC) Cell Chip with Human Peripheral Blood Monocytes, B Cells, NK Cells and Stem Cells...
Plasmacytoid dendritic cells, BDCA-4+, For immunohistochemistry (IHC) Cell Chip with Human Umbilical Cord Blood Dendritic Cells...
Biology Products: