Navigation Links
A tall story: New research adds to growing body of knowledge of genetics of height
Date:4/6/2008

Scientists are beginning to develop a clearer picture of what makes some people stand head and shoulders above the rest. A team of researchers who last year identified the first common version of a gene influencing height has now identified a further twenty regions of the genome which together can make a height difference of up to 6cm.

The results, published together with two independent studies online today in the journal Nature Genetics, mean that scientists now know of dozens of genes and genetic regions that influence our height. This provides scientists with a fascinating insight into how the body grows and develops normally and may shed light on diseases such as osteoarthritis and cancer.

Unlike a number of other body size characteristics such as obesity, which is caused by a mix of genetic and environmental factors (so called "nature and nurture"), 90 per cent of normal variation in human height is due to genetic factors rather than, for example, diet. Last year, a team of researchers including Dr Tim Frayling from the Peninsula Medical School, Exeter, and Professor Mark McCarthy from the University of Oxford identified the first common gene variant to affect height, though it made a difference of only 0.5cm.

Now, using DNA samples from over 30,000 people, many taken from the Wellcome Trust Case Control Consortium the largest study ever undertaken into the genetics underlying common diseases and from the Cambridge Genetics of Energy Metabolism (GEM) consortium and the CoLaus Study in Switzerland, the researchers have identified 20 loci (regions of genetic code), common variations of which influence adult height.

"The number and variety of genetic regions that we have found show that height is not just caused by a few genes operating in the long bones" says Dr Frayling. "Instead, our research implicates genes that could shed light on a whole range of important biological processes.

"By identifying which gen
'/>"/>

Contact: Craig Brierley
c.brierley@wellcome.ac.uk
44-207-611-7329
Wellcome Trust
Source:Eurekalert

Page: 1 2

Related biology news :

1. Synthetic molecules may be less expensive alternative to therapeutic antibodies, researchers find
2. Smithsonian researchers show major role of bats in plant protection
3. NC State researchers identify genes key to hormone production in plants
4. Veterinary college researchers explore function of biofilm in bovine respiratory disease
5. Carnegie Mellon researchers to curb CO2 emissions
6. Answering challenges of life in extreme environments research
7. Researchers confirm dead zone off Texas coast since 1985
8. MU researcher links hormone replacement therapy to breast cancer
9. Researchers to develop ocean sanctuary noise budget to evaluate potential impact on marine mammals
10. Michigan Tech researchers link 11 genetic variations to type 2 diabetes
11. Researcher discovers pathway plants use to fight back against pathogens
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... Monash University Professor Steven Chown has been awarded ... Medal for Excellence in Antarctic Research. , SCAR, ... coordinates high quality international scientific research in the ... Antarctic region in the Earth system. The organisation ... Antarctic Treaty System, responsible for governing the region. ...
(Date:7/30/2014)... injury (SCI), traumatic brain injury (TBI) and peripheral nerve ... learned over the past 30 years regarding both the ... growth, but this large body of information has not ... his team from University of Miami in USA proposed ... consensus is emerging that one contributing factor is a ...
(Date:7/30/2014)... SAN JOSE, Calif. , July 30, 2014 ... industry-academia partnership with the United States Air Force ... project proposed by Binghamton ... for human performance monitoring (HPM). The $425,000 project, ... and electronics packaging firm i3 Electronics, Inc. ( ...
Breaking Biology News(10 mins):Nano-Bio Manufacturing Consortium Awards Funding to Binghamton University for Development of Electronics and Biometric Sensor Platforms 2Nano-Bio Manufacturing Consortium Awards Funding to Binghamton University for Development of Electronics and Biometric Sensor Platforms 3
... multiple partners almost quadruples a teenager's risk of meningococcal ... today. , Meningococcal disease is a life threatening condition ... adolescence. , The incidence and fatality rate among ... during the 1990s, but little is known about the ...
... petty criminals gone wrong, researchers at the University of ... bacterial pathogens found in a number of troublesome diseases ... is carried out by disguising themselves, then hijacking their ... Affairs and Professor of Pharmacology and Cellular and Molecular ...
... biologists, developmental biologists and computer scientists at the Universtity ... the code for how gene expression is controlled. The ... January 2006. , A genome milestone was reached in ... This has been followed by complete chemical read-outs of ...
Cached Biology News:UCSD team unmasks family of immune system invaders 2UCSD team unmasks family of immune system invaders 3Cracking the genetic code for control of gene expression 2
(Date:7/30/2014)... , July 30, 2014 A study ... the safety and efficacy of CSL Behring,s C1 ... kidney transplants in highly sensitized patients. C1-INH is ... the complement system. The study shows ... increases in the levels of complement components 3 ...
(Date:7/30/2014)... (PRWEB) July 30, 2014 While ... in health services research for a relatively long ... in interest regarding the use of these ‘big ... conditions. , By combining today’s powerful computer technology ... digital era, ‘big data’ holds significant promise for ...
(Date:7/30/2014)... , July 30, 2014   Wyle ... Fully Integrated Lifecycle Mission Support Services (FILMSS) contract ... (NASA). Under the terms of the contract, Wyle ... at Moffett Field, Calif. In particular, Wyle will ... flight development projects on the International Space Station ...
(Date:7/30/2014)... MA (PRWEB) July 30, 2014 BCC ... Global Markets for Enzymes in Industrial Applications , ... reach to nearly $7.1 billion by 2018, registering a ... growth is estimated to be recorded in the detergent ... forecast period. , Enzyme technology has influenced almost every ...
Breaking Biology Technology:Study Suggests C1-INH May Aid in Prevention of Antibody-Mediated Rejection Following Kidney Transplant 2Study Suggests C1-INH May Aid in Prevention of Antibody-Mediated Rejection Following Kidney Transplant 3Leveraging ‘Big Data’ - Methodological Considerations in Health Services Research, New Webinar Hosted by Xtalks 2Wyle Wins NASA's Fully Integrated Lifecycle Mission Support Services Contract 2Global Market for Industrial Enzymes to Reach Nearly $7.1 Billion by 2018; Detergent Enzyme Market to Record Maximum Growth 2Global Market for Industrial Enzymes to Reach Nearly $7.1 Billion by 2018; Detergent Enzyme Market to Record Maximum Growth 3
... State University have discovered a way to make a low-cost ... radiation a goal first theorized in 1861 by a ... eluded wide practical use. Other materials can do this ... low-cost way that yields the same result will have extraordinary ...
... WAKE FOREST, N.C., Feb. 23, 2012 SiREM ... ) announced today the signing of a Sales ... terms of the agreement, Tersus Environmental will market, ... and KB-1® Plus – as well as Gene-Trac® ...
... International (NASDAQ: PRXL ), a leading ... von Rickenbach, Chairman and Chief Executive Officer of PAREXEL, ... Massachusetts Biotechnology Council (MassBio) CRO/CMO Symposium , to be ... Massachusetts. The symposium, organized by the MassBio Contract Research ...
Cached Biology Technology:Discovery opens door to low-cost 'negative refraction,' new products and industries 2PAREXEL Chairman and CEO to Deliver Keynote at MassBio CRO/CMO Symposium 2PAREXEL Chairman and CEO to Deliver Keynote at MassBio CRO/CMO Symposium 3PAREXEL Chairman and CEO to Deliver Keynote at MassBio CRO/CMO Symposium 4PAREXEL Chairman and CEO to Deliver Keynote at MassBio CRO/CMO Symposium 5
MOUSE ANTI RAT KAPPA/LAMBDA:HRP Immunogen: MARK-1: Rat kappa light chains (IR202 and IR968)MARL-15: Rat lambda light chains (RH58, IR31)...
Request Info...
SAIVI Alexa Fluor 680 injectable contrast agent *bovine serum albumin*...
RABBIT ANTI QUINOLINIC ACID...
Biology Products: