Navigation Links
A study using Drosophila flies reveals new regulatory mechanisms of cell migration
Date:3/21/2014

Cell migration is highly coordinated and occurs in processes such as embryonic development, wound healing, the formation of new blood vessels, and tumour cell invasion. For the successful control of cell movement, this process has to be determined and maintained with great precision. In this study, the scientists used tracheal cells of the fruit fly Drosophila melanogaster to unravel the signalling mechanism involved in the regulation of cell movements.

The research describes a new molecular component that controls the expression of a molecule named Fibroblast Growth Factor (FGF) in Drosophila embryos. The importance of FGF in cell migration was already known but little information was available on its genetic regulation. In the study, Arajo and her team have discovered that a protein called Hedgehog, known to be involved in morphogenesis, regulates FGF expression.

"This is the first time that a direct connection has been demonstrated between the Hedgehog pathway and an increase in FGF during cell migration," says Arajo.

"The results are really interesting for biomedicine," explains the researcher, "as the Hedgehog pathway is overexpressed in some of the most invasive tumours, such as the most common kind of skin cancer."

The team explains that this is a step forward for research into cell migration mechanisms and that future applications will emerge as further investigation and studies are conducted.


'/>"/>
Contact: Sònia Armengou
armengou@irbbarcelona.org
34-934-037-255
Institute for Research in Biomedicine (IRB Barcelona)
Source:Eurekalert  

Page: 1

Related biology news :

1. Wind farms can provide society a surplus of reliable clean energy, Stanford study finds
2. TGen study identifies gene fusion as likely cause of rare type of thyroid cancer
3. Study finds forest corridors help plants disperse their seeds
4. Diversity in UK gardens aiding fight to save threatened bumblebees, study suggests
5. The power of poison: Study examines pesticide poisoning of Africas wildlife
6. Study finds no evidence that vitamin D supplements reduce depression
7. Study of complete RNA collection of fruit fly uncovers unprecedented complexity
8. Study fingers chickens, quail, in spread of H7N9 influenza virus
9. Study finds that fast-moving cells in the human immune system walk in a stepwise manner
10. Motion and muscles dont always work in lockstep, researchers find in surprising new study
11. Study suggests potential association between soy formula and seizures in children with autism
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
A study using Drosophila flies reveals new regulatory mechanisms of cell migration
(Date:12/15/2016)... LONDON , Dec. 14, 2016 "Increase ... mobile biometrics market" The mobile biometrics market is expected ... USD 49.33 billion by 2022, at a CAGR of ... by factors such as the growing demand for smart ... mobile transactions. "Software component is expected to ...
(Date:12/7/2016)... According to a new market research report "Emotion Detection and Recognition Market by ... Area, End User, And Region - Global Forecast to 2021", published by MarketsandMarkets, ... to USD 36.07 Billion by 2021, at a Compound Annual Growth Rate (CAGR) ... ... MarketsandMarkets Logo ...
(Date:12/6/2016)... 2016  Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH) ... of €500.0 million principal amount of its 1.414% senior unsecured ... 2.425% senior unsecured notes due 2026. The ... 2016, subject to the satisfaction of customary closing conditions.  The ... The Company intends to use the net ...
Breaking Biology News(10 mins):
(Date:1/16/2017)... ... January 16, 2017 , ... ... Tibbetts Award from the U.S. Small Business Administration. The Tibbetts Award ... economic or social impact […] and are considered the best of the best ...
(Date:1/14/2017)... Diego, CA (PRWEB) , ... January 14, 2017 ... ... of Proximo™, a new service providing complete end-to-end genome assemblies to researchers around ... complete genomes eliminates a major obstacle in answering a wide range of scientific ...
(Date:1/13/2017)... , Jan 13, 2017 Research and Markets ... Manufacturing, Application - Global Forecast to 2021" report to their ... The ... from USD 3.39 Billion in 2016, at a CAGR of 26.3%. ... basis of product, manufacturing type, and application. Factors such as rising ...
(Date:1/13/2017)... ... 2017 , ... Two Kalamazoo entrepreneurs have launched AgTonik LLC ... farms, greenhouses and hydroponics operations use to increase yields and promote plant growth. ... of customers using this high grade fulvic acid extracted from a mineral deposit ...
Breaking Biology Technology: