Navigation Links
A study reveals how cells communicate to activate the cell division machinery
Date:5/5/2008

uture biomedical applications. Marco Miln goes on to say, this finding could provide clues about how to repress the cell proliferation signals in cancer.

The context is relevant

Furthermore, the research has elucidated the relationship between Notch and Wnt/Wingless in the control of proliferation and the development of the fly wing. In fact, Notch has a repressor function, that is to say, when it is activated the cell division machinery is arrested. Only when Wnt/Wingless starts to work is Notch silenced, thereby triggering the cascade of genes that allow proliferation. Notch works in this context as a tumor suppressor, explains Miln, while Wnt/Wingless acts as an oncogen, that is, by canceling the action of Notch it allows the cell division machinery to operate. But the fundamental point for the researchers is that Notch and Wnt/Wingless can interchange their roles depending on the context in which they are operating because the true executors of the action are the genes that these proteins regulate, in this case dMyc and bantam.

Researchers ask how, for example, in function of the tissue that is affected, Notch can serve as a tumor suppressor or as an oncogene. The conclusions drawn from this study, point to effectors being regulated by this pathway. We have highlighted the importance of the context in which these signaling pathways work and that knowledge about the underlying regulatory elements is crucial to understand how a certain function is performed, explains Herranz.

According to Miln, diseases like cancer cannot be understood without taking into account how the distinct elements are integrated: that is to say, crosstalk between neighboring cells, effector genes and cell cycle machinery. Now we must look for similarities in vertebrates and humans to see whether these elements work in the same way in diseases, concludes.


'/>"/>

Contact: Sonia Armengou
sonia.armengou@irbbarcelona.org
34-934-037-255
Institute for Research in Biomedicine (IRB Barcelona)
Source:Eurekalert

Page: 1 2

Related biology news :

1. Childhood obesity indicates greater risk of school absenteeism, Penn study reveals
2. A study by the MUHC and McGill University opens a new door to understanding cancer
3. Study begins to reveal clues to the cause and progression of sepsis
4. Clones on task serve greater good, evolutionary study shows
5. New study warns limited carbon market puts 20 percent of tropical forest at risk
6. New study examines how rearing environment can alter navigation
7. Study links cat disease to flame retardants in furniture and to pet food
8. New continent and species discovered in Atlantic study
9. Study shows link between alcohol consumption and hiv disease progression
10. Feeling hot, hot, hot: New study suggests ways to control fever-induced seizures
11. Study finds environmental tests help predict hospital-acquired Legionnaires disease risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... team of researchers from The Chinese University of Hong ... of wild soybean linked to salt tolerance, with implication ... soil. This study published online in Nature Communications ... information for crop improvement. , Soybean is an important ... selection, cultivated soybeans have less genetic diversities than their ...
(Date:7/11/2014)... group members to reduce aggression and gain access to ... grooming activities shows a certain pattern across the day. ... Biology Letters . , Grooming between individuals in ... motives. To be groomed has hygienic benefits and is ... can provide access to infants, mating opportunities and high ...
(Date:7/11/2014)... have explored two different ways that allow unprecedented ... the formation of oxygen molecules in photosynthesis. The ... journal Nature Communications . , "The new ... for water oxidation, which are key components for ... of solar energy in fuels like hydrogen, ethanol ...
Breaking Biology News(10 mins):BGI reports a novel gene for salt tolerance found in wild soybean 2Baboons groom early in the day to get benefits later 2Molecular snapshots of oxygen formation in photosynthesis 2
... are an important food source for fish and other aquatic ... this week in the Proceedings of the National Academy ... diets are supported by material that originates on land in ... to clarifying the role that watershed inputs play in aquatic ...
... BUFFALO, N.Y. -- An innovative, educational computing platform developed ... the cloud (remote, high-capacity, scalable servers) is helping UB ... new level. Soon, high-school and middle-school students will benefit ... by UB faculty members with a $250,000 National Science ...
... and Nanyang Technological University (NTU) are collaborating to enhance ... with oil., If successful, the wider application of the ... companies here to produce distilled water for their industrial ... at Singapore,s Jurong Island, which produce a lot of ...
Cached Biology News:Aquatic food web tied to land 2With cloud computing, the mathematics of evolution may get easier to learn 2With cloud computing, the mathematics of evolution may get easier to learn 3With cloud computing, the mathematics of evolution may get easier to learn 4memsys-NTU partnership to enhance water desalination technology 2
(Date:7/11/2014)...  Researchers have pioneered a revolutionary new way ... called Virtual Finger, allows scientists to move through ... synapses using the flat surface of their computer ... studies orders of magnitude more efficient, saving time, ... many areas of experimental biology. The software and ...
(Date:7/10/2014)... Product and process impurities in biopharmaceuticals ... are often “lost in the noise,” making their ... Dr. Rowel Tobias, Senior Scientist, Protein Chemistry at ... Quality at Nanotherapeutics, Inc., to lear about a ... and quantitation while achieving the required specificity and ...
(Date:7/10/2014)... Terascala, the industry leader in HPC ... former vice president of product management for Flexera Software, ... marketing. Terascala’s software when combined with leading compute and ... performance and most reliable solutions for processing big data. ... expansion and broaden its product portfolio. His leadership in ...
(Date:7/10/2014)... Angeles, CA (PRWEB) July 10, 2014 ... and Bioanalytical techniques during 18-20 August, 2014 at Double ... critically review the recent developments in Analytical & Bioanalytical ... the globe. , Speaking on this occasion, Dr. Srinubabu ... Analytica Acta conference is a remarkable one in ...
Breaking Biology Technology:Virtual Finger Enables Scientists To Navigate And Analyze 3D Images Of Complex Biological Structures 2Virtual Finger Enables Scientists To Navigate And Analyze 3D Images Of Complex Biological Structures 3Novel Ms Techniques Speed Detection of Biopharmaceutical Product and Process Impurities, New Webinar Hosted by Xtalks 2Terascala Expands Executive Team 2Terascala Expands Executive Team 3A Critical Review of Analytical Techniques for Improved Living Standards 2A Critical Review of Analytical Techniques for Improved Living Standards 3A Critical Review of Analytical Techniques for Improved Living Standards 4
... , , , For determining the optimal reagent for your cells , ... Contents , Kit Contents , Storage and Stability , ... Introduction , , , ... , , Effectene ...
... , QIAshredder spin columns are designed for simple and rapid homogenization , of cell ... , , Format: , ... , , Sample ... plant cell or tissue lysates, white blood cell lysates, , ...
... , , , Library siRNA is available against ... , Library siRNA is synthesised using patented TOM-Amidite chemistry, and , ... annealed, , desalted, and ready to use. A detailed certificate ... order. Library siRNAs are ready for transfection, , and are ...
Cached Biology Technology:Transfection Reagent Selector Kit Handbook 2Transfection Reagent Selector Kit Handbook 3Transfection Reagent Selector Kit Handbook 4Transfection Reagent Selector Kit Handbook 5Transfection Reagent Selector Kit Handbook 6Transfection Reagent Selector Kit Handbook 7Transfection Reagent Selector Kit Handbook 8Transfection Reagent Selector Kit Handbook 9Transfection Reagent Selector Kit Handbook 10Transfection Reagent Selector Kit Handbook 11Transfection Reagent Selector Kit Handbook 12Transfection Reagent Selector Kit Handbook 13Transfection Reagent Selector Kit Handbook 14Transfection Reagent Selector Kit Handbook 15Transfection Reagent Selector Kit Handbook 16Transfection Reagent Selector Kit Handbook 17Transfection Reagent Selector Kit Handbook 18Transfection Reagent Selector Kit Handbook 19Transfection Reagent Selector Kit Handbook 20Transfection Reagent Selector Kit Handbook 21Transfection Reagent Selector Kit Handbook 22Transfection Reagent Selector Kit Handbook 23Transfection Reagent Selector Kit Handbook 24Transfection Reagent Selector Kit Handbook 25Transfection Reagent Selector Kit Handbook 26Transfection Reagent Selector Kit Handbook 27Transfection Reagent Selector Kit Handbook 28Transfection Reagent Selector Kit Handbook 29Transfection Reagent Selector Kit Handbook 30QIAshredder Homogenizer 2
Mouse monoclonal to OCIL ( Abpromise for all tested applications)....
... SV40 Large T antigen initiates ... of replication in the presence ... This product can be used ... DNA Replication Kit cat. no. ...
NuParaffin Kit Application: Flow Cytometry Reactivity: Human...
Request Info...
Biology Products: