Navigation Links
A strategy to fix a broken heart
Date:8/9/2010

rofessor of pathology and bioengineering.

"The first thing that transplanted heart cells have to do is survive. And when you transition them from a culture dish to the body, initially they don't have a blood supply. So we have to promote the host blood supply as fast as possible," Murry said.

"We're very optimistic that this scaffold will help keep the muscle cells alive after implantation and will help transition them to working heart muscles," Murry said.

The scaffold is made from a jelly-like hydrogel material developed by first author, UW bioengineering doctoral student Lauran Madden. A needle is used to implant the tiny (third of a millimeter wide by 4 millimeters long) scaffold rods into the heart muscle. But the scaffold can support growth of larger clumps of heart tissue, Madden said.

The next steps will involve adjusting the scaffold degradation time so that the scaffold degrades at the same rate that cardiac cells proliferate and that blood vessels and support fibers grow in, and then implant a cell-laden scaffold into a damaged heart.

"What we have now is a really good system going in the dish, and we're working to transition it to in the body," Madden said.

Beat BioTherapeutics, a Seattle startup co-founded by Ratner, Murry and co-author Michael Laflamme, a UW assistant professor of pathology, plans to license the technology to help bring it to patients.


'/>"/>

Contact: Hannah Hickey
hickeyh@uw.edu
206-543-2580
University of Washington
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. UM School of Medicine scientists develop new strategy that may improve cognition
2. Molecular discovery suggests new strategy to fight cancer drug resistance
3. Scientists call for a new strategy for polar ocean observation
4. Flus evolution strategy strikes perfect balance
5. A new effective strategy for treating tobacco addiction was developed by researchers from the CAS
6. Physics strategy tested as solution for antibiotic resistance
7. Novel strategy for generating induced pluripotent stem cells for clinical use is safe and efficient
8. Global study shows health joins green as business strategy
9. Novel Parkinsons treatment strategy involves cell transplantation
10. Study highlights forest protected areas as a critical strategy for slowing climate change
11. Plants discover the benefits of good neighbors in strategy against herbivores
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
A strategy to fix a broken heart
(Date:10/22/2014)... BEDFORD, Mass., Oct. 21, 2014 Aware, Inc. (NASDAQ: ... and services, today reported financial results for its third quarter ... quarter of 2014 was $6.0 million, an increase of 40% ... Operating income in the third quarter of 2014 was $4.1 ... 2013. Higher operating income in the current three month period ...
(Date:10/17/2014)... is critical and pertinent for practicing physicians and clinicians ... epidemic. The Journal, Disaster Medicine and Public Health ... and Public Health, to surround the public, medical professionals ... moment. , On October 17, the journal published ... primer was prepared by Dr. Eric Toner, internist and ...
(Date:10/16/2014)... and Mary,s Virginia Institute of Marine Science have ... Protection Agency to identify the streams and wetlands ... tools to help local governments and citizens conserve ... on a dataset of tidal-marsh observations first gathered ... this historical baseline can today,s researchers accurately map ...
Breaking Biology News(10 mins):Aware, Inc. Reports Third Quarter 2014 Financial Results 2Aware, Inc. Reports Third Quarter 2014 Financial Results 3Aware, Inc. Reports Third Quarter 2014 Financial Results 4Aware, Inc. Reports Third Quarter 2014 Financial Results 5Aware, Inc. Reports Third Quarter 2014 Financial Results 6Aware, Inc. Reports Third Quarter 2014 Financial Results 7EPA grant will help localities conserve headwater wetlands 2EPA grant will help localities conserve headwater wetlands 3
... tragic Gulf oil spill has faded from nightly television newscasts ... tragic accident are still with us today. In their new ... Dilemma," Joseph Tainter and Tadeusz Patzek explain the real causal ... history. This disaster was not an isolated incident. ...
... Kan. -- Scientists may soon be able to make pest ... models for new technologies, all thanks to a tiny finding ... doctoral candidate in biochemistry, Pune, India, is the senior author ... Proceedings of the National Academy of Sciences , also ...
... nearly sixty atmospheric pollutants have been studied using the ... 1996 to 2009. Concentrations of pollutants in Lapland are ... concentrations in Southern Finland. Many of the concentrations studied ... showed a decreasing trend. Lower concentrations were ...
Cached Biology News:From protein to planes and pigskin 2From protein to planes and pigskin 3Air quality has continued to improve in Finnish Lapland 2
(Date:10/22/2014)... The Americas Inorganic Refrigerants Market report defines and ... analysis and forecast of revenue. , Browse through ... report, to get an idea of the in-depth ... the segmentation in the Americas inorganic refrigerants market, ... , http://www.micromarketmonitor.com/market/americas-inorganic-refrigerants-4191654241.html , Inorganic refrigerants ...
(Date:10/22/2014)... (PRWEB) October 22, 2014 Currently ... Sartorius, A & D Weighing, Rice Lake, and ... Semi-Micro Balance . The Sartorius CPA Semi-Micro Balance ... affordable high-quality, precise, and user-friendly laboratory balance. , ... laboratory equipment, their laboratory balances are well known ...
(Date:10/22/2014)... 2014 /PRNewswire/ - iCo Therapeutics ("iCo" or "the Company") ... for its Oral Amphotericin B program.  The company ... vitro work involving samples from HIV/AIDS patients ... complete pre clinical studies and regulatory filings to ... trial, utilizing approximately $700,000 of funding and technological ...
(Date:10/20/2014)... Mapp Biopharmaceutical,s valiant effort to produce ... fight the Ebola outbreak will make the public ... of pharmaceuticals can be, according to Kalorama Information.  ... some may be taken aback by the three-month ... knowledge are well aware of the complex issues ...
Breaking Biology Technology:The Americas Inorganic Refrigerants Market is estimated to grow to $71.6 million by 2018 - New Report by MicroMarket Monitor 2The Americas Inorganic Refrigerants Market is estimated to grow to $71.6 million by 2018 - New Report by MicroMarket Monitor 3Pipette.com Launches the Addition of Sartorius CPA Semi-Micro Balance to Their Product Portfolio with Special Promotional Pricing 2Pipette.com Launches the Addition of Sartorius CPA Semi-Micro Balance to Their Product Portfolio with Special Promotional Pricing 3iCo Therapeutics Announces Advancement of Oral Amphotericin B Program 2iCo Therapeutics Announces Advancement of Oral Amphotericin B Program 3Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 2Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 3
... Biosciences, Inc. (Nasdaq: RDEA ) announced today that ... present at the following upcoming investor conferences: ... 10:00 a.m. EDT on Monday, June 6, 2011. Wells ... EDT on Wednesday, June 22, 2011. ...
... 2011 Reportlinker.com announces that a new ... catalogue: Biochips and Microarrays ... http://www.reportlinker.com/p0350354/Biochips-and-Microarrays---Technologiesmarkets-and-companies.html?utm_source=prnewswire&utm_medium=pr&utm_campaign=Genomics This report ... on technologies and applications. The report starts ...
... grant from the National Institutes of Health (NIH), Arizona State ... world,s smallest molecular motors works in living cells. In the ... that has perplexed scientists for more than 40 years. ... examines the Fo molecular motor, its mechanism of action and ...
Cached Biology Technology:Ardea Biosciences to Present at Upcoming Investor Conferences 2Reportlinker Adds Biochips and Microarrays - Technologies, markets and companies 2Reportlinker Adds Biochips and Microarrays - Technologies, markets and companies 3NIH grant ratchets up ASU research in molecular motors 2NIH grant ratchets up ASU research in molecular motors 3
Human/Rat Neurogenin-2 MAb (Clone 7G4) Protein Family: Neural Crest Cell Markers, Transcription Factors...
Rat CINC-2 alpha/beta Affinity Purified Polyclonal Ab...
Monkey IL-2 ELISPOT Kit with white/opague microtiter plates...
Mouse TREM-2 Affinity Purified Polyclonal Ab...
Biology Products: