Navigation Links
'A stark warning:' Smoking causes genetic damage within minutes after inhaling
Date:1/15/2011

WASHINGTON, Jan. 15, 2011 In research described as "a stark warning" to those tempted to start smoking, scientists are reporting that cigarette smoke begins to cause genetic damage within minutes not years after inhalation into the lungs.

Their report, the first human study to detail the way certain substances in tobacco cause DNA damage linked to cancer, appears in Chemical Research in Toxicology, one of 38 peer-reviewed scientific journals published by the American Chemical Society.

Stephen S. Hecht, Ph.D., and colleagues point out in the report that lung cancer claims a global toll of 3,000 lives each day, largely as a result of cigarette smoking. Smoking also is linked to at least 18 other types of cancer. Evidence indicates that harmful substances in tobacco smoke termed polycyclic aromatic hydrocarbons, or PAHs, are one of the culprits in causing lung cancer. Until now, however, scientists had not detailed the specific way in which the PAHs in cigarette smoke cause DNA damage in humans.

The scientists added a labeled PAH, phenanthrene, to cigarettes and tracked its fate in 12 volunteers who smoked the cigarettes. They found that phenanthrene quickly forms a toxic substance in the blood known to trash DNA, causing mutations that can cause cancer. The smokers developed maximum levels of the substance in a time frame that surprised even the researchers: Just 15-30 minutes after the volunteers finished smoking. Researchers said the effect is so fast that it's equivalent to injecting the substance directly into the bloodstream.

"This study is unique," writes Hecht, an internationally recognized expert on cancer-causing substances found in cigarette smoke and smokeless tobacco. "It is the first to investigate human metabolism of a PAH specifically delivered by inhalation in cigarette smoke, without interference by other sources of exposure such as air pollution or the diet. The results reported here should serve as
'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1 2

Related biology news :

1. Dr. George Stark receives 2011 Herbert Tabor/Journal of Biological Chemistry Lectureship from ASBMB
2. School attendance, refusal skills combat smoking risk in youth
3. Study reveals cancer-linked epigenetic effects of smoking
4. Smoking during pregnancy may harm the childs motor control and coordination
5. Personalized approach to smoking cessation may be reality in 3-5 years
6. MSU researchers testing vaccine to help people quit smoking
7. Gene fusions may be the smoking gun in prostate cancer development, U-M study finds
8. Children living in apartments with nonsmoking adults still exposed
9. Smoking during radiation therapy for head and neck cancers linked to poorer outcomes
10. GUMC to develop smoking cessation aids based on unconventional nicotine addiction theory
11. Obesity and passive smoking reduce oxygen supply to unborn baby
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... 13, 2014. The fire is human-caused and is ... in size and is mostly being fueled by grass ... night due to higher humidity. Yesterday (8/15), firefighters ... construct a fireline on the West and North sides of ... fire: , 7 20-person Crews, 4 Hot Shot Crews, 1 ...
(Date:9/16/2014)... take up residence in and on the human body ... according to new research at Washington University School of ... individuals carry about five types of viruses on their ... Biology . The study is the first comprehensive analysis ... , The research was conducted as part of ...
(Date:9/16/2014)... for the dinosaurs 66 million years ago decimated the ... extent than their deciduous peers, according to a study ... the journal PLOS Biology . , Applying ... fossilized leaves of angiosperms flowering plants excluding ... ecology of a diverse plant community thriving during a ...
Breaking Biology News(10 mins):Healthy humans make nice homes for viruses 2Healthy humans make nice homes for viruses 3Meteorite that doomed dinosaurs remade forests 2Meteorite that doomed dinosaurs remade forests 3Meteorite that doomed dinosaurs remade forests 4
... at Chicago have discovered how some bacteria can survive ... to the drugs. The findings, published in the April ... to more effective antibiotics to treat a variety of ... pathogenic microbes can turn on the genes that protect ...
... Cleveland Botanical Garden and Kent State Universitys Liquid Crystal ... explore the potential of liquid crystal technology for creating ... held on Wade Oval, the Garden and the University ... the first phase of the project. One contains ...
... Roque Vinicio Cspedes, a junior at the University of ... a minor in Spanish, has been awarded a prestigious ... SOARS is a paid summer research internship for undergraduate ... This summer Cspedes will travel to Boulder, Colo. and ...
Cached Biology News:UIC scientists discover how some bacteria survive antibiotics 2'Smart' greenhouse research partnership unveiled 2Meteorology student SOARS toward excellence, overcomes obstacles 2
(Date:9/16/2014)... -- Biocom, the association representing the Southern California ... Annual National Health Information Technology Week, which brings ... our health care system. " ... most vibrant hubs for health IT and digital health ... testing to remote patient monitoring," said Joe Panetta ...
(Date:9/16/2014)... (PRWEB) September 16, 2014 ... world’s most efficient method for delivering dissolved gases ... Equipment Inc. as a manufacturer’s representative firm ... gas dissolution products for municipal water and wastewater ... Quebec. , H2Flow was founded in 1992 and ...
(Date:9/16/2014)... 16, 2014  The Council for Entrepreneurial Development ... in the country, today released a mid-year update ... It showed that in the first ... startups in the technology, life science, advanced ... from a variety of sources. Significant investment in technology ...
(Date:9/16/2014)... Ky. , Sept. 16, 2014  LABSCO, ... technologies and products to hospitals, physician office laboratories ... that, effective October 1, 2014, it will serve ... specified hospital market segments and as a semi-exclusive ... the 48 contiguous United States ...
Breaking Biology Technology:Biocom Recognizes National Health IT Week 2BlueInGreen® Expands into Canada – Signs Representative Agreement with H2Flow Equipment Inc. 2CED's Mid-Year Update to its Innovators Report Shows NC Startups Attracting Investment From Across the Globe with Several High-Profile Investment Deals, IPOs and Acquisitions Signaling Strength of Entrepreneurial Sector 2CED's Mid-Year Update to its Innovators Report Shows NC Startups Attracting Investment From Across the Globe with Several High-Profile Investment Deals, IPOs and Acquisitions Signaling Strength of Entrepreneurial Sector 3CED's Mid-Year Update to its Innovators Report Shows NC Startups Attracting Investment From Across the Globe with Several High-Profile Investment Deals, IPOs and Acquisitions Signaling Strength of Entrepreneurial Sector 4LABSCO Secures Alliance With Siemens Healthcare Diagnostics 2LABSCO Secures Alliance With Siemens Healthcare Diagnostics 3
... Oxford Finance Corporation (Oxford), a subsidiary of Sumitomo Corporation, ... Sanborn to its Business Development group. As director, Business ... life science companies, primarily in western North America. ... a lender and equity investor, banker, executive and entrepreneur. ...
... may be better ways to engineer the planet,s climate ... University of Calgary climate scientist says in two new ... in a condensable vapour above the Earth, are two ... sulphur dioxide gas into the atmosphere," says David Keith, ...
... that a new market research report is available ... markets and companies http://www.reportlinker.com/p0203545/Nanobiotechnologies--applications-markets-and-companies.html ... and utilization of materials, devices, and systems through ... (a nanometer is one billionth of a meter. ...
Cached Biology Technology:U of C scientist offers better ways to engineer Earth's climate to prevent dangerous global warming 2U of C scientist offers better ways to engineer Earth's climate to prevent dangerous global warming 3U of C scientist offers better ways to engineer Earth's climate to prevent dangerous global warming 4Reportlinker Adds Nanobiotechnologies- Applications, Markets and Companies 2Reportlinker Adds Nanobiotechnologies- Applications, Markets and Companies 3Reportlinker Adds Nanobiotechnologies- Applications, Markets and Companies 4Reportlinker Adds Nanobiotechnologies- Applications, Markets and Companies 5Reportlinker Adds Nanobiotechnologies- Applications, Markets and Companies 6Reportlinker Adds Nanobiotechnologies- Applications, Markets and Companies 7Reportlinker Adds Nanobiotechnologies- Applications, Markets and Companies 8Reportlinker Adds Nanobiotechnologies- Applications, Markets and Companies 9Reportlinker Adds Nanobiotechnologies- Applications, Markets and Companies 10Reportlinker Adds Nanobiotechnologies- Applications, Markets and Companies 11Reportlinker Adds Nanobiotechnologies- Applications, Markets and Companies 12Reportlinker Adds Nanobiotechnologies- Applications, Markets and Companies 13Reportlinker Adds Nanobiotechnologies- Applications, Markets and Companies 14Reportlinker Adds Nanobiotechnologies- Applications, Markets and Companies 15Reportlinker Adds Nanobiotechnologies- Applications, Markets and Companies 16Reportlinker Adds Nanobiotechnologies- Applications, Markets and Companies 17Reportlinker Adds Nanobiotechnologies- Applications, Markets and Companies 18Reportlinker Adds Nanobiotechnologies- Applications, Markets and Companies 19Reportlinker Adds Nanobiotechnologies- Applications, Markets and Companies 20Reportlinker Adds Nanobiotechnologies- Applications, Markets and Companies 21
Self Closing Forceps...
... cells right in your 35mm dish ... dish Perfusion Chamber has separate openings ... dampen the fluctuations of the liquid ... prevent bubbles from entering the chamber. ...
... cells (BTI-TN-5B1-4) derived from Trichoplusia ni ... to be capable of expressing significantly ... compared to other insect cells. High ... doubling time as adherent cultures- Quick adaptation ...
... steadylite plus assay system offers ... sensitivity, Designed for batch-processing systems, ... higher density microplates such as ... free, Convenient storage conditions ( ...
Biology Products: