Navigation Links
A revolutionary new 3-D digital brain atlas
Date:6/21/2013

processing complete histological sections of the brain.

The advance in resolution is analogous to the transition from older line maps to Google satellite images. Zooming into older maps provides no more detail or information. Similarly, zooming into an MRI scan provides no further detail it just reveals the blocky 1mm pixellation. The BigBrain brain atlas is the equivalent of Google street view, zooming in provides a new level of information that hasn't been offered before in 3D.

Current atlases based on histological slices are in 2D. BigBrain redefines these traditional neuroanatomy maps such as those of Brodmann by providing an ultra-view of the brain using fully automated 3D techniques. Atlases based on MRIs do not allow for the integration of information at the level of cortical layers, columns, micro circuits, or the larger cells. BigBrain enables researchers to see at 20 micron resolution (1000 microns in a millimetre) throughout the brain.

The implications of BigBrain to explore and analyze the human brain are innumerable. It can be used to integrate and correlate data from a wide range of modalities: genetic, molecular neuroscience, electrophysiological and pharmacological among many. It will enable and accelerate computational modelling for simulation of brain functions, normal development and degeneration caused by disease. BigBrain will vastly improve the importance and interpretation of low-resolution dynamic in-vivo data obtained by MRI and PET, by combining the data with the enormous detail and spatial resolution of the static BigBrain atlas. It will enhance neurosurgical procedures, for example placing deep brain stimulators and will advance clinical research, for example, localizing the site of intractable epilepsy to certain specific type of nerve cells.


'/>"/>

Contact: Anita Kar
anita.kar@mcgill.ca
514-398-3376
McGill University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Revolutionary Face Recognition Media Exploitation System Now Available to Enhance Public Safety in Europe
2. Carnegie debuts revolutionary biosphere mapping capability at AGU
3. DARPA director: Revolutionary weapons require strong S&T partnerships
4. Physicists explore properties of electrons in revolutionary material
5. WHOI scientists/engineers partner with companies to market revolutionary new instruments
6. Sandia seeks commercial partners for revolutionary SpinDx medical diagnostic tool
7. Revolutionary project will obtain entire genome sequences in fight against Alzheimers
8. DigitalPersona Announces U.are.U Software Development Kit (SDK) for Android Applications
9. LASIK Goes Digital
10. Papa Johns Restaurants in China Speed and Secure Workflow with DigitalPersona Fingerprint Biometrics
11. DigitalPersona Fingerprint Readers Receive STQC Certification for UIDAI Program in India
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... Salk professor and Howard Hughes Medical Institute investigator, ... named recipients in the 2014 round of grants ... the BRAIN (Brain Research through Advancing Innovative Neurotechnologies) ... announced September 30, provides more than $3 million ... years. , The BRAIN Initiative, launched last year, ...
(Date:9/30/2014)... water may increase the risk of stillbirth and ... by a Boston University School of Public Health ... Environmental Health , compared 1,091 PCE-exposed pregnancies ... Cape Cod, Ma., where water was contaminated in ... the installation of vinyl-lined asbestos cement pipes. PCE ...
(Date:9/30/2014)... live in almost any aquatic environment on Earth, but ... species are pushed to the limit. The amount of ... critical for how different species cope in the future, ... of Gothenburg, published in the scientific journal Proceedings ... continues apace thanks to increasing levels of greenhouse gases ...
Breaking Biology News(10 mins):Salk scientists receive $3 million for BRAIN Initiative grant 2Contaminated water linked to pregnancy complications, BU study finds 2Shape up quickly -- applies to fish, too! 2
... in ecological or environmental conservation remains contentious the ... demand that governments regulate and encourage restoration projects; ... corporations makes such interventions politically difficult. However, ... a handful of developing nations, alongside South Africa, ...
... , RIVERSIDE, Calif. Alan McHughen , a ... University of California, Riverside, has been chosen by the ... Sciences to receive a 2011-2012 Jefferson Science Fellowship ... selected for the fellowships this year. Successful ...
... is redefining the rules by which we live and at ... level, several areas of the globe are in danger of ... and maybe, one day, live in floating houses. Depending ... others in their adjustment to the effects of global warming, ...
Cached Biology News:UC Riverside plant biotechnologist receives prestigious Jefferson Science Fellowship 2UC Riverside plant biotechnologist receives prestigious Jefferson Science Fellowship 3Floating houses 2Floating houses 3
(Date:9/30/2014)... , September 30, 2014 ... intuitive browsing of chemistry in documents ... software solutions and consulting services for life science ... information and generate Markush structures from documents. ... organizations intellectual property, however generating and understanding Markush ...
(Date:9/30/2014)... Sept. 30, 2014 FemCap Inc., www.femcap.com ... its receipt of a patent No: US, 8,795,248 B2 ... also received FDA clearance in the U.S., 510(K) K121857, ... in Europe. This patent is related to its menstrual cup ... the company is releasing FemmyCycle Teen, a third menstrual ...
(Date:9/30/2014)... SoundConnect, an award ... dedicated to supporting business communication solutions, including business ... a carrier services specialist has joined ... connected and productive at all times. This growth ... businesses to cloud communications services. On a ...
(Date:9/30/2014)... Back in the 1970’s, many companies calculated their ... which included space for circulation and file storage. “It ... at Nidea Corporate Real Estate / ITRA Global , ... 2000, however, 250 square feet per employee became the ... to 175 to 225 square feet, and over the next ...
Breaking Biology Technology:ChemAxon Introduces ChemCurator for Chemical Information Extraction and Markush Structure Creation 2The FemmyCycle 2SoundConnect Expands Carrier Services Division 2ITRA Global Reports on How Companies Are Squeezing More Employees into Less Office Space 2ITRA Global Reports on How Companies Are Squeezing More Employees into Less Office Space 3
... , ... , , , Antibodies ... arrays) or as biopharmaceutical therapeutics. In,all cases the successful production ... criteria include: protein identification,quantitation and the monitoring of purity and ...
... , ... , , , ... of the Agilent 2100 bioanalyzer in combination,with the Protein 200 Plus ... denaturing gel-elctrophoresis (SDSPAGE).,The results showed that the Agilent 2100 bioanalyzer provides,fast ...
... , ... , , , , ... an siRNA sequence,for a target gene, which are of,high importance ... crucial.,An efficient method to optimize,transfection and gene silencing,is critical for ...
Cached Biology Technology:Quality control of antibodies using the,2100 bioanalyzer and the Protein 200,Plus assay 2Quality control of antibodies using the,2100 bioanalyzer and the Protein 200,Plus assay 3Comparison of different protein,quantitation methods 2Comparison of different protein,quantitation methods 3Comparison of different protein,quantitation methods 4Comparison of different protein,quantitation methods 5Comparison of different protein,quantitation methods 6Comparison of different protein,quantitation methods 7Comparison of different protein,quantitation methods 8Comparison of different protein,quantitation methods 9Confirming gene silencing,mechanism by pGFP/GFP22 ,siRNA co-transfection 2Confirming gene silencing,mechanism by pGFP/GFP22 ,siRNA co-transfection 3Confirming gene silencing,mechanism by pGFP/GFP22 ,siRNA co-transfection 4