Navigation Links
A recent IRCM breakthrough impacts cancer research
Date:10/28/2010

"Our team identified three regions in ELMO that allow it to toggle between a closed/inactive and open/active shape," adds Dr. Yoran Margaron, a postdoctoral fellow in the same research unit and one of the article's co-authors. "We showed that if we disrupt ELMO's regulatory feature and maintain the protein in an open state, we can fully activate the DOCK180/Rac pathway and significantly increase the migration potential of cells."

The researchers' next step is to investigate the regulation of ELMO in cancer cells. Based on their latest findings, they will attempt to maintain ELMO in a repressed state within cancer cells to prevent metastasis, which could have a major impact on the development of potential cancer treatments.


'/>"/>

Contact: Julie Langelier
julie.langelier@ircm.qc.ca
514-987-5555
Institut de recherches cliniques de Montreal
Source:Eurekalert

Page: 1 2

Related biology news :

1. Sea Grant report synthesizes recent research on New Yorks clams
2. Recent news reports of sweetener reformulations raise questions about motivations
3. Autism Speaks responds to recent publications citing autism clusters in California
4. Arctic lake sediments show warming, unique ecological changes in recent decades
5. Ongoing human evolution could explain recent rise in certain disorders
6. Recently analyzed fossil was not human ancestor as claimed, anthropologists say
7. BIO-key(R) International Biometric Accuracy Improved by More Than 23% as Reported in Recent NIST Testing
8. At opening of XVIII International AIDS Conference, scientific, community and political leaders applaud recent progress toward universal access and urge continued momentum to finish what weve started
9. Risk of surgery for Crohns disease lower than reported in recent studies
10. Breakthrough optical technology to assess colon cancer risk, accuracy
11. Sandia, SES win Popular Mechanics Breakthrough Innovator Award
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/1/2014)... prairies and forests of the world can also be ... to a surprising new study led by Colorado State ... The research team analyzed 596 soil samples collected from ... diversity of below-ground life, most of which had never ... 16.2 percent of the organisms discovered in the park ...
(Date:9/30/2014)... of moorland burning is published today in the first ... of relieving tensions on both sides of the grouse ... Moorland Burning on the Ecohydrology of River basins) project ... practised predominantly to support red grouse populations for gun ... chemistry and physical properties, river water chemistry and river ...
(Date:9/30/2014)... --- Do we think of nature as something that we ... need to "preserve?" Or do we think of ourselves as ... of nature, but what about a house? , The ... also reflected in our actions, our speech and in cultural ... the University of Washington, the American Indian Center of Chicago ...
Breaking Biology News(10 mins):Microbes in Central Park soil: If they can make it there, they can make it anywhere 2Microbes in Central Park soil: If they can make it there, they can make it anywhere 3Grouse moor burning causes widespread environmental changes 2The cultural side of science communication 2
... Helsinki and Sibelius Academy, Helsinki, the neurobiological basis ... evaluated using candidate genes associated in the earlier ... data consisted of 343 family members from 19 ... and/or active amateurs. The musical aptitude was assessed ...
... In a new study published in Disease Models & ... the influence of known cancer genes on the development and ... with limited treatment options. Inside the cell, signals are ... or even die. Cancer often results when the molecules ...
... Thank parasites for making some of our immune proteins into ... genetics study that will appear in the June 8 issue ... 25). The study, conducted by a team of researchers in ... some of those genes into risk factors for intestinal disorders. ...
Cached Biology News:The neurobiology of musicality related to the intrinsic attachment behavior? 2Zebrafish provide a model for cancerous melanoma in humans 2Immune genes adapt to parasites 2
(Date:10/1/2014)... The U.S. Department of Labor has ... Edwardsville as part of the Trade Adjustment Assistance Community ... co-administered by the Department of Labor and Department of ... Thomas E. Perez and Secretary of Education Arne Duncan ... grants to nearly 270 colleges across the country. ...
(Date:9/30/2014)... in German . ... dots in a semiconductor layer. Quantum dots are small structures ... If a short laser pulse is fired at the photonic ... experiences a change in the electromagnetic field around it. This ... light by the dot. As soon as the refractive index ...
(Date:9/30/2014)... AMHERST, Mass. Using a bio-mimicking analog of ... of grass, an international research team led by ... has taken a major step in developing long-sought ... to electricity for use in electronic devices. ... UMass Amherst and others at Stanford University and ...
(Date:9/30/2014)... Shimadzu Scientific Instruments has released the DSES-1000 ... tool for measuring displacement in rubber and other ... movement distance, the DSES-1000 can measure elongations up ... 10 mm. In addition, it achieves +/- 0.2 ... within +/- 100 µm below 50-mm stroke. , ...
Breaking Biology Technology:U.S. Dept. of Labor Awards SIUE Nearly $10-Million Grant 2U.S. Dept. of Labor Awards SIUE Nearly $10-Million Grant 3U.S. Dept. of Labor Awards SIUE Nearly $10-Million Grant 4Ultrafast remote switching of light emission 2Blades of grass inspire advance in organic solar cells 2Blades of grass inspire advance in organic solar cells 3Shimadzu’s New Long-Travel Extensometer Increases Precision for Soft Material Testing 2
... In biological research laboratories, filtration techniques are performed to sterilize ... and separate and purify samples for processing. In most cases, ... The majority of filtration tasks ... 50 Torr (25 28Hg). A number of plastic labware ...
... , In this ... merits. A comprehensive examination of four Information Dependent Acquisition (IDA) survey ... found. A significant number of metabolites were found with each mode ... from glyburide. , Overview ...
... Purpose , ... Q TRAP LC/MS/MS system with Metabolite ID software for Phase I and ... productivity and confidence in your results. , ... Current trends in drug development are placing more emphasis on characterization of ...
Cached Biology Technology: Improving the Efficiency of Common Filtration Tasks in your Laboratory 2 Improving the Efficiency of Common Filtration Tasks in your Laboratory 3Strategies to Identify and Confirm Phase I Metabolites of Glyburide Using the 4000 Q TRAP System 2Strategies to Identify and Confirm Phase I Metabolites of Glyburide Using the 4000 Q TRAP System 3Strategies to Identify and Confirm Phase I Metabolites of Glyburide Using the 4000 Q TRAP System 4Strategies to Identify and Confirm Phase I Metabolites of Glyburide Using the 4000 Q TRAP System 5Strategies to Identify and Confirm Phase I Metabolites of Glyburide Using the 4000 Q TRAP System 6Identification of Phase I and Phase II Metabolites of Buspirone on the Q TRAP LC/MS/MS System 2Identification of Phase I and Phase II Metabolites of Buspirone on the Q TRAP LC/MS/MS System 3Identification of Phase I and Phase II Metabolites of Buspirone on the Q TRAP LC/MS/MS System 4Identification of Phase I and Phase II Metabolites of Buspirone on the Q TRAP LC/MS/MS System 5
Request Info...
Agarose-LE, 500 g. Suitable for soft agarose cloning. Nuclease-free.Gel point (1.5%): 36 1.5 C, EEO (-mr): 1200 g/cm2. Category: Nucleotides & Enzymes & Biochemicals, Ultrapure Biochemicals ....
Request Info...
Request Info...
Biology Products: