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A protein that protects against Alzheimer's?
Date:1/6/2009

ective and reparative role of this protein.

When can we expect medication?

A number of steps remain before this research can translate into effective drugs against neurodegenerative conditions. The original investigator, Professor ric Rassart, explains, "You cannot simply inject ApoD, as it has to enter the brain in order for it to be active. We have successfully demonstrated the role of ApoD, but now we need to understand the action of this protein. Only then will we be able to think about creating a drug to prevent these types of diseases and to slow their progression. All the same, this discovery by Sonia Do Carmo and her collaborators is a significant breakthrough, as we know very little about the mechanisms of neurodegenerative diseases."

The discovery has aroused considerable interest among the molecular biology community. Two major scientific journals have already published the research findings: Aging Cell (Vol. 7: 506-515, 2008) and Journal of Neuroscience (Vol. 28: 10330-10338, 2008).


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Contact: Claire Bouchard
bouchard.claire@uqam.ca
514-987-3000
Universit du Qubec Montral
Source:Eurekalert

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