Navigation Links
A non-invasive intracellular 'thermometer' with fluorescent proteins has been created
Date:5/23/2012

ecules receive, and that which they emit later, to be measured. In the words of Quidant, "this difference in polarization (anisotropy) is directly connected to the rotating of the GFP molecules and therefore with temperature".

The green fluorescence of the proteins has a reward

The authors of the study ensure that biologists will be able to implement this technique in experimental set-ups and obtain the cell temperature as another observable detail. In 2008, when Osamu Shimomura, Martin Chalfie and Roger Y. Tsien won the Nobel Chemistry Prize for discovering and developing GFP, they resolved many complications in biomedical research.

In the field of molecular biology, different techniques have been suggested to monitor internal cell temperature, these researchers found limitations in measuring the intensity and spectrum of its fluorescence.

Furthermore, the option of measuring intracellular activity could establish the basis to develop a field that has not been widely studied: thermal biology at cellular level.

According to the authors of the study, the following step is to improve the method's sensitivity and resolution. In order to achieve that, the researchers work to fine tune the properties of the fluorescent proteins and optimise the detection method of its 'thermometer'.


'/>"/>
Contact: SINC
info@agenciasinc.es
34-914-251-820
FECYT - Spanish Foundation for Science and Technology
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Potential for non-invasive brain tumor treatment
2. Non-invasive cultivar? Buyer beware
3. Tel Aviv University President Co-authors Important Paper Unraveling the Effect of Spatial Organization on Intracellular Chemistry
4. Intracellular express -- why transport protein molecules have brakes
5. Development of a FRET sensor for real-time imaging of intracellular redox dynamics
6. End of an era: NIST to cease calibrating mercury thermometers
7. Researchers create new class of fluorescent dyes to detect reactive oxygen species in vivo
8. Fluorescent proteins illuminating biomedical research
9. Pitt-led researchers create quick, simple fluorescent detector for TB
10. Fluorescent cancer cells to guide brain surgeons
11. Penn researchers demonstrate a new model for drug discovery with a fluorescent anesthetic
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
A non-invasive intracellular 'thermometer' with fluorescent proteins has been created
(Date:5/17/2013)... day, insects provide the white noise of the South, but ... year, the Southern air hangs heavy from the humidity and ... more than 140 species of frogs, toads and salamanders, is ... the ponds and swamps are the auditorium for their symphonic ... and Monitoring Initiative, or ARMI, have front-row seats. ...
(Date:5/17/2013)... all ages will celebrate the science and technology ... daily lives during the inaugural Atlanta Science Festival, ... from local museums, corporations, K-12 schools and universities, ... events for children and adults at venues across ... , The annual Atlanta Science Festival is ...
(Date:5/17/2013)... Shenzhen, China---- Why Tibetan antelope can live at ... a collaborative research published in Nature Communications ... institutes provide evidence that some genetic factors may ... highland environments. The data in this work will ... and the biology of other ruminant species. , ...
Breaking Biology News(10 mins):Front-row seats to climate change 2Front-row seats to climate change 3Front-row seats to climate change 4First Atlanta Science Festival set for 2014 2The genome sequence of Tibetan antelope sheds new light on high-altitude adaptation 2
... gibbons, arboreal primates that inhabit the jungles of Southeast Asia, ... in the genomes of all other primates, including humans. This ... approximately 25 million years ago. Their results are reported ... Research . , Agouti signaling protein ( ASIP ) was ...
... two novel genes within the tumors of women with early ... and are not at risk for early relapse or cancer-related ... April 1 issue of Clinical Cancer Research. , "The HOXB13 ... marker of relapse in hormone-receptor positive breast cancer treated with ...
... cancer-causing virus that was thought to be unimportant for its ... initiate an infection and to reproduce. , The study ... a protein it makes called p13. The protein is one ... done in laboratory-grown cells suggested that the virus could live ...
Cached Biology News:Major obesity gene is 'lost in the shuffle' 2Mayo Clinic study finds two genes predict outcome for breast cancer patients 2Cancer virus protein needed for successful infection 2
(Date:5/20/2013)... Interventional cardiologist Tony Farah, MD, and his ... Cardiovascular Institute have helped pioneer many breakthroughs in ... over the past three decades, from new disease-fighting medications ... artery stent implantation. , Today, AGH officials announced that ... in the study of a novel, first-of-its kind investigational ...
(Date:5/20/2013)... 2013 In Early 2013, Dr. ... biotoxin related illnesses , announced his vision for creating ... advance his protocol for treating Chronic Inflammatory Response Syndrome ... physician to achieve certification in the Shoemaker Protocol. ... practice the Shoemaker Protocol in other parts of the ...
(Date:5/17/2013)... 2013 Dr. Sparano is Professor of ... at the Albert Einstein College of Medicine and Associate ... Medical Center. He is also Associate Director for ... the Einstein Breast Cancer Working Group, a multidisciplinary group ... research. He also serves as Vice Chair of the ...
(Date:5/17/2013)... (PRWEB) May 17, 2013 The new ... Photonics21 at the association’s recent annual meeting drew ... EC Vice-President Neelie Kroes, who called the action “a ... and a stimulant to European innovation.” , The Board ... of the new Photonics PPP at its 29 April ...
Breaking Biology Technology:Allegheny General Hospital Cardiovascular Institute Becomes Exclusive Pittsburgh Site for Study of Novel Coronary Artery Disease Device 2Allegheny General Hospital Cardiovascular Institute Becomes Exclusive Pittsburgh Site for Study of Novel Coronary Artery Disease Device 3Allegheny General Hospital Cardiovascular Institute Becomes Exclusive Pittsburgh Site for Study of Novel Coronary Artery Disease Device 4Dr. Ritchie Shoemaker Certifies Third Physician in His Treatment Protocol for Chronic Inflammatory Response Syndrome (CIRS) 2Joseph A. Sparano, MD, Named Vice Chair of ECOG-ACRIN Cancer Research Group 2Joseph A. Sparano, MD, Named Vice Chair of ECOG-ACRIN Cancer Research Group 3SPIE Joins in Praise for ‘Huge Step Forward’ for Innovation R&D Enabled by Photonics21 Actions 2SPIE Joins in Praise for ‘Huge Step Forward’ for Innovation R&D Enabled by Photonics21 Actions 3
... ... Safety Solutions Continues to Accelerate., , ... (PRWEB) June 22, 2010 -- iCardiac Technologies, Inc. , a ... top 20 pharmaceutical companies have recently selected iCardiac as a preferred vendor. iCardiac ...
... 21 A global research team led by scientists ... new study in the Proceedings of the National Academy of ... genome. Lead author, Ewen Kirkness , Ph.D., JCVI, directed ... of the genome was then conducted by a large international ...
... 21 Dyadic International, Inc. (Pink Sheets: DYAI), ... addresses the needs of the multi-billion dollar biofuels market ... biomass into ethanol and other forms of alternative energy, ... firm, The Abraham Group, to provide strategic advice and ...
Cached Biology Technology:Three Top 20 Pharmaceutical Companies Select iCardiac as Preferred Vendor 2Multinational Research Team Led by J. Craig Venter Institute's Ewen Kirkness Sequence Body Louse Genome 2Multinational Research Team Led by J. Craig Venter Institute's Ewen Kirkness Sequence Body Louse Genome 3Dyadic International Engages The Abraham Group as Strategic Advisor 2Dyadic International Engages The Abraham Group as Strategic Advisor 3Dyadic International Engages The Abraham Group as Strategic Advisor 4
ICC Diluent Buffer 250 ml...
This antibody is specific for human J-chain as defined by ELISA assay using purified human immunoglobulin fragments as solid phase target antigen....
...
Tissue-Stat ( Tissue Adherent for Mounting Formalin-Fixed and Frozen Tissue Sections.)...
Biology Products: