Navigation Links
A new nuance to neurons
Date:8/23/2011

pecialized cells with very long extensions sometimes a meter or more in length.

Down these spaghetti-like nerve fibers travel electrical impulses, which will cause the neuron to release some of these tiny vesicle sacs, spilling their chemical contents into the synapse, a gap between the nerve ending and the next neuron. The chemicals then seep over to the adjoining neuron, sometimes triggering it to fire in turn.

This basic game of neurotransmission is played trillions of times over by the 10 billion or so neurons in the human brain. Some neurons are so active that they fire as many as 100 times a second, requiring mechanisms to sustain these high rates.

The vesicles play a crucial role in this process because they allow neurons to fire when ready. Neurons use the vesicles to package the chemicals and transport them in advance so that they can release as soon as an electrical impulse arrives. Since the release sites are far away from the cell center, the vesicles must recycle locally to maintain high rates of release.

For years, scientists have observed that while all vesicles appear identical, they actually exist in two different pools. The smaller pool, found at the extreme land's end of the neuron, holds the ones that release neurotransmitters when an electrical impulse arrives. After release, the vesicles are quickly recycled for continued use, and for this reason scientists have called this the "recycling" pool of vesicles.

The second pool of vesicles can be much larger, accounting for up to 80 percent of all the vesicles at a synapse. Surprisingly, these vesicles do not respond to electrical impulses. Instead they sit dormant when the signal arrives and, because of this, scientists have dubbed this the "resting" pool.

"It's not clear what they respond to or what their function is," Edwards said.

Because the vesicles in the two pools appear to be identical under the microscope, nobody knew if the
'/>"/>

Contact: Jason Socrates Bardi
jason.bardi@ucsf.edu
415-502-4608
University of California - San Francisco
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Stabilizing force for good communication between neurons and muscle cells found
2. Mediator in communication between neurons and muscle cells found
3. Protecting neurons could halt Alzheimers, Parkinsons diseases
4. How mirror neurons allow us to learn and socialize by going through the motions in the head
5. Researchers generate functional neurons from somatic cells
6. UCLA stem cells scientists make electrically active motor neurons from iPS cells
7. ORNL, St. Jude track neurons to predict and prevent disease
8. Basic guides to PCR, labeling neurons featured in Cold Spring Harbor Protocols
9. Phasic firing of dopamine neurons is key to brains prediction of rewards
10. Alzheimer cell death in Zebrafish: Demise of neurons observed live for the first time
11. Impaired transport in neurons triggers prion disease
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
A new nuance to neurons
(Date:6/18/2015)... YORK , June 18, 2015 This ... US$ Million by the following Product Segments, which includes ... Systems, Chemiluminescence Immunoassay Systems, Radio Immunoassay Systems, and Nephelometric ... the US, Canada , ... Asia-Pacific , Latin America ...
(Date:6/17/2015)... Calif. , June 17, 2015  Synaptics ... human interface solutions, today announced that Xiaomi, one ... the Synaptics ® ClearPad ® family ... display driver integrated circuits (DDICs) for its latest ... By leveraging ClearPad for full in-cell display solutions ...
(Date:6/16/2015)... , June 16, 2015 Fingerprint Cards ... fingerprint sensors in the company,s portfolio from one of its ... planned to mainly take place during the third quarter 2015. ... Asia . Jörgen Lantto, CEO of ...   the   growing interest from smartphone OEMs in integrating ...
Breaking Biology News(10 mins):Global Immunoassay Systems Market 2Global Immunoassay Systems Market 3Global Immunoassay Systems Market 4Global Immunoassay Systems Market 5Global Immunoassay Systems Market 6Global Immunoassay Systems Market 7Global Immunoassay Systems Market 8Global Immunoassay Systems Market 9Global Immunoassay Systems Market 10Global Immunoassay Systems Market 11Global Immunoassay Systems Market 12Global Immunoassay Systems Market 13Global Immunoassay Systems Market 14Global Immunoassay Systems Market 15Global Immunoassay Systems Market 16Global Immunoassay Systems Market 17Global Immunoassay Systems Market 18Global Immunoassay Systems Market 19Global Immunoassay Systems Market 20Global Immunoassay Systems Market 21Global Immunoassay Systems Market 22Global Immunoassay Systems Market 23Global Immunoassay Systems Market 24Global Immunoassay Systems Market 25Global Immunoassay Systems Market 26Global Immunoassay Systems Market 27Global Immunoassay Systems Market 28Global Immunoassay Systems Market 29Synaptics Touchscreen and Display Driver IC Solutions Power Xiaomi's Latest Flagship Smartphones 2Synaptics Touchscreen and Display Driver IC Solutions Power Xiaomi's Latest Flagship Smartphones 3FPC Receives Order for Touch Fingerprint Sensors of 375 MSEK 2
... November 18, 2008 The American Journal of Preventive ... will be featured at the "Changing Climate Changing ... event is Guest Editor Howard Frumkin, MD, DrPH, speaking ... "Climate change is a key public health challenge. ...
... Internationally recognized climate scientist and economist Jae Edmonds ... carbon capture and sequestration in climate stabilization in the ... Greenhouse Gas Technologies. He is one of nearly a ... National Laboratory who will present new findings and insights ...
... Biologists at Washington University in St. Louis have made major ... potentially harmful genes. Differential gene expression ... For instance, although every cell in the human body ... get activated to make an eye different from a toe. ...
Cached Biology News:Issues at intersection of climate change and health impact global well-being 2Issues at intersection of climate change and health impact global well-being 3Issues at intersection of climate change and health impact global well-being 4PNNL leadership in carbon sequestration featured at international conference 2New gene-silencing pathway found in plants 2New gene-silencing pathway found in plants 3New gene-silencing pathway found in plants 4
(Date:7/3/2015)... ... July 03, 2015 , ... ... industry-leading products for use in applications such as animal waste reduction, bioremediation, ... plants and restaurant kitchen settings, announced today that it will be showcasing, ...
(Date:7/3/2015)... , July 3, 2015 ... voivat hakea verkossa osoitteessa  http://www.openinnovationinscience.at ... Open Innovation in Science" -jatkokoulutusohjelmaan ... Boltzmann Gesellschaftin (LBG) tekemän, kansainvälisiä ... mukaan terveystieteiden kaksi suurinta haastetta ...
(Date:7/3/2015)... ... July 03, 2015 , ... The Alexander Group, ... professional service industries alike-- typically known for its consummate professionalism-- embarks each year ... cause and break from their day jobs. , "Our motto has always been ...
(Date:7/3/2015)... ... 03, 2015 , ... The global failure analysis market is expected to reach ... bioscience market is expected to grow at the highest CAGR of 8.46%; its growth ... the research labs and academic institutions for root cause analysis of failure. The market ...
Breaking Biology Technology:DryLet to Highlight Benefits of Patented ManureMagic™ at North American Manure Expo in Chambersburg, PA July 14-15, 2015 2Maailman ensimmäinen tiedemiesten koulutukseen suunniteltu avoimen innovaation ohjelma käynnistyy 2Maailman ensimmäinen tiedemiesten koulutukseen suunniteltu avoimen innovaation ohjelma käynnistyy 3The Alexander Group Declares Their Independence with a Bit of Levity 2Failure Analysis Market to Grow at 7.52% CAGR to 2020 2Failure Analysis Market to Grow at 7.52% CAGR to 2020 3Failure Analysis Market to Grow at 7.52% CAGR to 2020 4Failure Analysis Market to Grow at 7.52% CAGR to 2020 5
... , IRVINE, Calif., Aug. 31 ... of Pulse CO-Oximetry(TM) and Measure-Through Motion and Low-Perfusion pulse oximetry, ... the Thomas Weisel Partners Healthcare Conference 2009 at the Four ... at 10:20 a.m. EDT. A live audiocast of the ...
... NOVATO, Calif., Aug. 31 Raptor Pharmaceuticals Corp. ("Raptor" ... will hold its 2009 Annual Meeting of Stockholders on Monday, September ... at 9 Commercial Blvd., Suite 200, Novato, California. All stockholders of ... at such annual meeting and all stockholders of Raptor are invited ...
... , , , ... ARAY ), a global leader in the field ... treatment planning capabilities of the CyberKnife(R) Robotic Radiosurgery System at ... (ESTRO) Conference on Physics and Radiation Technology for Clinical Radiotherapy ...
Cached Biology Technology:Masimo to Present at the Thomas Weisel Partners Healthcare Conference 2009 2Raptor Pharmaceuticals Schedules 2009 Annual Meeting of Stockholders 2Raptor Pharmaceuticals Schedules 2009 Annual Meeting of Stockholders 3Accuray to Showcase CyberKnife Treatment Planning Capabilities at Preeminent Radiation Oncology Conference 2Accuray to Showcase CyberKnife Treatment Planning Capabilities at Preeminent Radiation Oncology Conference 3Accuray to Showcase CyberKnife Treatment Planning Capabilities at Preeminent Radiation Oncology Conference 4