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A new indicator for breast cancer relapse identified
Date:6/19/2012

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The results obtained from this project have opened up new roads of investigation that will have to centre on identifying the pharmaceuticals that induce the expression of the 14-3-3 protein sigma in breast tumours and characterise their effect on tumour cells. They also hope to define which genes activated by the NF-kB complex are important for tumour progression in this group of patients and to study their potential as possible therapeutic targets.

According to Espinosa 'This opens up the possibility of researching and employing specific therapeutic strategies for this concrete group of patients who, in principle, have bad prognoses and an especially high risk of relapse'.

The study was initially led and developed at the IMIM by Dr Llus Espinosa's and Anna Bigas' group and collaboration from researchers and doctors from the Hospital del Mar, the Jimenez Daz Foundation, the Barcelona Institute of Biomedical Research (IRB) and Pompeu Fabra University.


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Contact: Marta Calsina
mcalsina@imim.es
34-933-160-680
IMIM (Hospital del Mar Research Institute)
Source:Eurekalert

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