Navigation Links
A new candidate pathway for treating visceral obesity
Date:5/6/2012

by oxidizing fat (a chemical reaction involving oxygen) in their research.

Especially exciting for the prospects of targeting Aldh1a1 for therapeutic benefit, the researchers found that knocking down expression of the Aldh1a1 gene by injecting antisense molecules into mice made fat by diet resulted in less visceral fat, less weight gain, lower glucose levels, and protection against cold exposure as compared to control mice.

"Brown fat, and mechanisms that might allow white fat to take on brown fat characteristics, has been receiving increasing attention as a possible way to treat obesity and its complications," said Plutzky. "Although more work is needed, we can add specific aspects of retinoid metabolism to those factors that appear involved in determining white versus brown fat."

According to the Centers for Disease Control and Prevention, one-third of adults in the United States are obese. Current methods to reduce obesity include exercise, dietary therapy, medications and surgery.


'/>"/>

Contact: Lori J. Shanks
ljshanks@partners.org
617-534-1604
Brigham and Women's Hospital
Source:Eurekalert

Page: 1 2

Related biology news :

1. Voters prefer candidates with deep voices
2. Promising results in mice on needle-free candidate universal vaccine against various flu viruses
3. Scientists discover new drug candidates for cystic fibrosis and other diseases
4. First genome-wide association study for dengue identifies candidate susceptibility genes
5. TB vaccine candidate shows early promise
6. Scientists find new drug candidates for set of protein-folding diseases
7. The impact of candidates statements about climate change on electoral success
8. Team awarded $7.5 million to identify potential drug candidates to treat nicotine addiction
9. Novartis and collaborators discover novel antimalarial drug candidate
10. Lexicon to Present Clinical Data for Diabetes Drug Candidate, LX4211, at Two Major Healthcare Conferences
11. Researchers discover weak link in Alzheimers drug candidates
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/13/2015)... YORK , April 13, 2015 ... by TechSci Research, "Global Biometrics Market Forecast & Opportunities, ... register a CAGR of around 14% till 2020. ... governments for large scale implementation and review of ... and launch of new products with greater efficiency, ...
(Date:4/6/2015)... , Apr. 6, 2015 NXT-ID, Inc. (NASDAQ: ... biometric authentication company focused on the growing mobile ... provisional patent 62/143028 for MINIATURE, MULTI-PURPOSE ... TRANSFER  NXT-ID introduces a new revolutionary ... patent surrounds the use of miniature antenna modules ...
(Date:4/1/2015)... 2015  NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... the growing mobile commerce market, announces the second shipment ... underway to early access pre-order customers. ... retail outlets including Walmart, Target, AT&T, Dunkin, Donuts, Stop ... accepted at all outlets and very easy to use. ...
Breaking Biology News(10 mins):Global Biometrics Market to Cross US$ 21 Billion by 2020: TechSci Research 2NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 2NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 3NXT-ID Patents Miniature, Low Power Wireless Magnetic Stripe 4NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 2NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 3NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 4
... for the once almost universally fatal childhood cancer acute ... near future, thanks to improvements in diagnosis and treatment ... St. Jude Children's Research Hospital. Almost 4,000 cases of ... about two-thirds of which are in children and adolescents, ...
... A new study by Rebecca Baggaley, Neil Ferguson, and ... HIV epidemic in poor countries will not be controlled ... achieved. As they demonstrate in an article in the ... methods such as counseling patients and their communities about ...
... the first clear proof that global warming is causing outbreaks ... populations and driving many species to extinction. , Published in ... reveals how the warming may alter the dynamics of a ... disease, the author's say, has hundreds of species around the ...
Cached Biology News:St. Jude projects 90 percent cure rate for ALL 2St. Jude projects 90 percent cure rate for ALL 3St. Jude projects 90 percent cure rate for ALL 4St. Jude projects 90 percent cure rate for ALL 5Access to antiretrovirals unlikely to reduce HIV infection rates 2Climate change drives widespread amphibian extinctions 2
(Date:4/30/2015)... , April 30, 2015 /PRNewswire/ - BioAmber Inc. (NYSE: ... chemicals, today announced that it has commenced an underwritten public ... to grant the underwriters a 30-day option to purchase ... of common stock offered in the public offering. The ... be no assurance as to whether or when the ...
(Date:4/30/2015)... , April 30, 2015 The following is an ... Directors of China Cord Blood Corp (NYSE: CO ) ... committee of the independent directors of China Cord Blood Corp ... offer of $6.40 per share from Golden Meditech Holdings Co ... per share would greatly benefit Golden Med and Mr. Kam, ...
(Date:4/30/2015)... SAN DIEGO , April 30, 2015 /PRNewswire/ ... company engaged in the development of biosimilar therapeutics ... today announced the closing of its previously announced ... common stock at a public offering price of ... full by the underwriters of their option to ...
(Date:4/30/2015)... WuXi PharmaTech (Cayman) Inc. ("WuXi" or the ... R&D services provider, today announced that its board of ... April 29, 2015, from a consortium (the "Consortium") led ... chairman and chief executive officer of the Company, and ... transaction (the "Transaction") involving the acquisition of all outstanding ...
Breaking Biology Technology:BioAmber Inc. Announces Public Offering Of Common Stock 2BioAmber Inc. Announces Public Offering Of Common Stock 3April 30, 2015 Open Letter to the Board of China Cord Blood Corp from Jayhawk Capital 2April 30, 2015 Open Letter to the Board of China Cord Blood Corp from Jayhawk Capital 3April 30, 2015 Open Letter to the Board of China Cord Blood Corp from Jayhawk Capital 4April 30, 2015 Open Letter to the Board of China Cord Blood Corp from Jayhawk Capital 5Pfenex Inc. Announces Closing of Public Offering of Common Stock and Full Exercise of Underwriters' Option to Purchase Additional Shares 2WuXi PharmaTech Announces Receipt of Proposal 2WuXi PharmaTech Announces Receipt of Proposal 3WuXi PharmaTech Announces Receipt of Proposal 4WuXi PharmaTech Announces Receipt of Proposal 5WuXi PharmaTech Announces Receipt of Proposal 6
... Advance Ganaxolone Program for the Treatment of EpilepsyBRANFORD, Conn., ... drugs to treat serious neurological and psychiatric disorders, today ... financing. The funding comes on the heels of the ... ganaxolone as an adjunctive therapy in adults with partial ...
... Ohio State University researchers have developed a new strategy ... grand challenge in physics. , What they,ve discovered could ... of new high-tech materials. , In 2008, the Defense ... to tackle an ambitious problem: trap atoms inside a ...
... Copan Diagnostics, Inc. is proud to announce the first ... Vancouver General Hospital. Copan WASP(R): Walk-Away Specimen Processor is ... samples. The breakthrough technology behind the WASP, coupled with ... automation, make the WASP the first instrument of its ...
Cached Biology Technology:Marinus Pharmaceuticals Raises $20 Million in Series B Financing 2Marinus Pharmaceuticals Raises $20 Million in Series B Financing 3Marinus Pharmaceuticals Raises $20 Million in Series B Financing 4Marinus Pharmaceuticals Raises $20 Million in Series B Financing 5Physicists discover important step for making light crystals 2Physicists discover important step for making light crystals 3Vancouver General Hospital is the First Canadian Institution to Implement Copan WASP(R): Walk-Away Specimen Processor 2
... EKMax™ is a recombinant preparation of ... EKMax™ Enterokinase is expressed and isolated from ... highly purified enzyme preparation (2). It recognizes ... bond after the lysine residue. The enzyme ...
... (rat) - Diluted Antiserum for RIA, Host: ... U-23 (rat) Immunology Products, Host: Rabbit ... our corresponding peptide and 1 ... Neuromedin U-23 (rat) (H-9295) and ([ 1 ...
...
...
Biology Products: