Navigation Links
A new application allows online statistical analysis of gene-expression data

The journal Computers in Biology and Medicine has published an article on the new IT application BootstRatio, created by IDIBELL researchers. The application allows online statistical analysis of data from gene expression. It is accessible through and any scientist is already to use it.

Researchers at the Human Molecular Genetics group at IDIBELL, led by Dr. Virginia Nunes, had a problem to provide signification to the results of statistical analyses of gene expression data. Most of the statistical calculations which are done to compare gene expression data assume a normal distribution of data and this distribution is not always real.

Together with Ramon Clries, statistician at IDIBELL's Cancer Prevention and Control group, Dr. Nunes decided to work on a statistical analysis using resampling techniques that allows to generate a hypothetical distribution of the data without any initial distribution and exposing the data in a comprehensible language to the scientist.

That was the beginning of BootstRatio, which can be accessed from a remote server. "After the researcher enters the data, in a few time the program sends the results via email in a comprehensible language to the scientist," explains Miguel Lopez de Heredia, CIBERER researcher at the Human Molecular Genetics group at IDIBELL. "Statisticians and biologists sometimes speak different languages. This new tool allows a biological interpretation of the results of statistical analysis. "

Dr. Clries explains that the application BootstRatio "is very easy to use and it doesn't require statistical expertise."


Contact: Arantxa Mena
IDIBELL-Bellvitge Biomedical Research Institute

Page: 1

Related biology news :

1. Nanotechnology in Medical Applications: The Global Market
2. Cell Therapeutics, Inc. Expects That the European Medicines Agencys (EMA) Committee for Medicinal Products for Human Use (CHMP) May Issue an Opinion on the Marketing Authorization Application ("MAA") on Pixuvri™ in Mid-February
3. Quantitative imaging application to gut and ear cells are reported in 2 Nature papers
4. Manipulating way bacteria talk could have practical applications, Texas A&M profs say
5. SomaLogic and Ambergen announce agreement for commercial applications of photocleavable biotin
6. Mechanical stress can help or hinder wound healing depending on time of application
7. Aware Develops Next-Generation Biometric Enrollment Application for Department of Justice
8. DigitalPersona Showcases Fingerprint Biometrics for Civil ID Applications at the Biometric Consortium Conference
9. Flexible electronics hold promise for consumer applications
10. Hebrew University student turns paper mill waste into green material for industrial applications
11. Groundbreaking new journal on the applications of digital games to human health
Post Your Comments:
(Date:11/12/2015)...   Growing need for low-cost, easy to ... paving the way for use of biochemical sensors ... in clinical, agricultural, environmental, food and defense applications. ... medical applications, however, their adoption is increasing in ... emphasis on improving product quality and growing need ...
(Date:11/9/2015)... Calif. , Nov. 9, 2015  Synaptics Inc. ... interface solutions, today announced broader entry into the automotive ... solutions that match the pace of consumer electronics human ... biometric sensors are ideal for the automotive industry and ... Europe , ...
(Date:10/29/2015)... 2015 Daon, a global leader in mobile ... a new version of its IdentityX Platform , ... America have already installed IdentityX v4.0 and ... FIDO UAF certified server component as an ... FIDO features. These customers include some of the largest ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... Malaysia , Nov. 24, 2015  Asia-Pacific ... contract research organisation (CRO) market. The trend of ... in lower margins but higher volume share for ... capacity and scale, however, margins in the CRO ... Organisation (CRO) Market ( ), finds ...
(Date:11/24/2015)... 2015 Cepheid (NASDAQ: CPHD ) today ... following conference, and invited investors to participate via webcast. ...      Tuesday, December 1, 2015 at 11.00 a.m. Eastern Time ...      Tuesday, December 1, 2015 at 11.00 a.m. Eastern Time ... New York, NY      Tuesday, December 1, 2015 ...
(Date:11/24/2015)... /CNW/ - iCo Therapeutics ("iCo" or "the Company") (TSX-V: ... the quarter ended September 30, 2015. Amounts, unless ... presented under International Financial Reporting Standards ("IFRS"). ... Andrew Rae , President & CEO of ... only value enriching for this clinical program, but ...
(Date:11/24/2015)... ... 2015 , ... International Society for Pharmaceutical Engineering (ISPE) closed ... events for pharmaceutical manufacturing: 2015 Annual Meeting. The conference took place in Philadelphia, ... number of attendees in more than a decade. , “The 2015 Annual ...
Breaking Biology Technology: