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A multidisciplinary approach and a new field help to understand cell behavior
Date:11/21/2012

amily of epidermal growth factor receptors that is, how a cellular chemical chain reaction goes awry to create cancer. To answer this fundamental question, Dr. Lidke stimulates cells at precise times and in a precise order using tiny chambers and pumps developed by Sandia National Labs' microfluidics teams. She then uses newly-developed imaging technologies, such as hyperspectral microscopy and super-resolution microscopy, to look at particular molecules within the stimulated cells.

These new technologies use cutting-edge physics, chemistry, engineering and mathematics to produce and analyze images but they also create a previously unknown problem. "These imaging technologies are generating vast amounts of data," says Dr. Oliver. "The bottleneck now is the image analysis. Microscopists are generating so much data that they must use entirely new analysis techniques." So the second part of the conference is a series of interactive sessions led by physicists, mathematicians and engineers to advance the fields of data capture, large dataset analysis, and imaging data analysis. The scientists will share ideas about ways to organize the overwhelmingly large sets of data and to distill important information from them.

"The partnership between Sandia National Labs and the UNM Cancer Center has really helped to bring this conference together," says Dr. Oliver. "We're thrilled to engage physical scientists and engineers in answering biological questions about cancer."


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Contact: Janet Oliver
joliver@salud.unm.edu
University of New Mexico Cancer Center
Source:Eurekalert

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