Navigation Links
A mother’s nutrition--before pregnancy--may alter the function of her children’s genes
Date:9/20/2012

Bethesda, MDEveryone knows that what mom eats when pregnant makes a huge difference in the health of her child. Now, new research in mice suggests that what she ate before pregnancy might be important too. According to a new research report published online in The FASEB Journal, what a group of female mice atebefore pregnancychemically altered their DNA and these changes were passed to her offspring. These DNA alterations, called "epigenetic" changes, drastically affected the pups' metabolism of many essential fatty acids. These results could have a profound impact on future research for diabetes, obesity, cancer, and immune disorders.

"As parents, we have to understand better that our responsibilities to our children are not only of a social, economical, or educational nature, but that our own biological status can contribute to the fate of our children, and this effect can be long-lasting," said Mihai Niculescu, M.D., Ph.D., study author from Nutrition Research Institute at the University of North Carolina at Chapel Hill, in Chapel Hill, N.C. "My hope is that, along with many other scientists, we will reveal this tight biological relationship between us as parents, and our children, and how we can improve the lives of our children using our own biological machinery."

To make this discovery, Niculescu and colleagues split mouse females into two groups before gestation, and fed them either a control diet, or a diet deficient in alpha-linolenic acid or ALA. This was achieved by replacing the type of fats in the diet, while keeping the number of calories the same. The females were bred with mouse males kept on a control diet. Immediately after the moms delivered the pups, each of these two initial groups were further split in two, so that each half of the initial groups received a flaxseed oil supplemented diet (rich in ALA), while the other halves from each group remained on the same d
'/>"/>

Contact: cmooneyhan@faseb.org
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1 2

Related biology news :

1. U of M faculty find antimicrobials altering intestinal bacteria composition in swine
2. Farmer-led irrigation schemes could alter food security in sub-Saharan Africa, South Asia
3. Intense prep for law school admission test alters brain structure
4. Natural regeneration building urban forests, altering species composition
5. Acute stress alters control of gene activity
6. New process doubles production of alternative fuel while slashing costs
7. Gene mutations linked to most cases of rare disorder -- Alternating Hemoplegia of Childhood
8. Gastric bypass surgery alters gut microbiota profile along the intestine
9. Toward an alternative for antibiotics to fight bacterial infections?
10. Amniotic fluid yields alternatives to embryonic stem cells
11. Scripps Research Institute Scientists Develop Alternative to Gene Therapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... 2014 Aware, Inc. (NASDAQ: AWRE ), ... financial results for its third quarter ended September 30, 2014. ... $6.0 million, an increase of 40% compared to $4.3 million ... third quarter of 2014 was $4.1 million compared to $1.0 ... in the current three month period was primarily due to: ...
(Date:10/18/2014)... patients with undiagnosed, suspected genetic conditions, a certain type ... molecular diagnostic yield than traditional molecular diagnostic methods, according ... study is being released to coincide with the American ... which sequences the protein­coding region of the genome (the ... a cell or organism), has been rapidly applied in ...
(Date:10/17/2014)... news release is available in German . ... only a very few drugs. When treating overdoses, doctors are ... is especially difficult if there is a combination of drugs ... playing and accidentally swallows his grandmother,s pills? ETH professor Jean-Christophe ... wanted to find an answer to this question. "The task ...
Breaking Biology News(10 mins):Aware, Inc. Reports Third Quarter 2014 Financial Results 2Aware, Inc. Reports Third Quarter 2014 Financial Results 3Aware, Inc. Reports Third Quarter 2014 Financial Results 4Aware, Inc. Reports Third Quarter 2014 Financial Results 5Aware, Inc. Reports Third Quarter 2014 Financial Results 6Aware, Inc. Reports Third Quarter 2014 Financial Results 7Study examines type of exome sequencing and molecular diagnostic yield 2Study examines type of exome sequencing and molecular diagnostic yield 3Emergency aid for overdoses 2Emergency aid for overdoses 3
... and physicists from the Alfred Wegener Institute, Helmholtz Centre ... all of the Southern Hemisphere humpback whales ( Megaptera ... of the Antarctic summer. Part of the population remains ... report this in a current issue of scientific journal ...
... 8, 2013 An ambitious partnership among more than ... Gamble,s (P&G,s) nonprofit program, Children,s Safe Drinking ... billion quarts of clean drinking water to families in ... just getting started. CSDW Manager Allison Tummon Kamphuis, ...
... of our health-conscious times and is seen as an important ... salt in the diet and specifically sodium is ... pressure however, scientists have found that salt,s other oft-overlooked constituent ... by researchers at the University of Glasgow has revealed that ...
Cached Biology News:Surprising underwater-sounds: Humpback whales also spend their winter in Antarctica 2Surprising underwater-sounds: Humpback whales also spend their winter in Antarctica 3Surprising underwater-sounds: Humpback whales also spend their winter in Antarctica 4Water-purification plant the size of a fast-food ketchup packet saves lives 2Yin-yang effect of sodium and chloride presents salt conundrum 2
(Date:10/22/2014)... Khaimah, UAE (PRWEB) October 22, 2014 ... life science and healthcare projects, announces the addition of ... DRCOG DCH to its advisory team. Dr. Siddiqui will ... team. , A graduate of University College ... was subsequently degreed in medicine in 2001. With further ...
(Date:10/22/2014)... , Oct. 22, 2014 Nuvilex, Inc. ... approximately 400 million people worldwide are living with diabetes, ... people by 2030.  The global market for diabetes treatments ... approximately 330,000 people worldwide died from pancreatic cancer.  Pancreatic ... due to cancer in the United States ...
(Date:10/20/2014)... Texas (PRWEB) October 20, 2014 ... announced that a team from Iowa State University won ... design contest. Using a Convey HC-2ex, the team’s solution ... 14 times faster than the second place finisher. , ... world embarked upon the month long challenge, using a ...
(Date:10/20/2014)... -- PureTech , a science and technology ... announced today the closing of a $55 million ... Perpetual, a $120 Billion group of funds. The ... pipeline forward and to advance new healthcare related ... to really go for the big ideas that ...
Breaking Biology Technology:Dr. Yousef Siddiqui joins the Grace Century Advisory Team 2Nuvilex Brief Analyst Report: Thinking Outside the Box by BrokerBank Securities, Inc. 2Team from Iowa State Wins 2014 MemoCODE Design Contest Using Convey HC-2ex 2Team from Iowa State Wins 2014 MemoCODE Design Contest Using Convey HC-2ex 3PureTech Announces Expansion with Oversubscribed $55M Funding Round 2PureTech Announces Expansion with Oversubscribed $55M Funding Round 3PureTech Announces Expansion with Oversubscribed $55M Funding Round 4PureTech Announces Expansion with Oversubscribed $55M Funding Round 5PureTech Announces Expansion with Oversubscribed $55M Funding Round 6
... N.J., Nov. 19 Synvista Therapeutics, Inc. (AMEX: ... the FDA has received its application for 510(k) clearance for its ... review process, during which the FDA will determine whether the kit ... in vitro diagnostic. , , ...
... 19 Bavarian Nordic,has invoiced the U.S. authorities ... allowed under the RFP-3 contract to manufacture and ... vaccine. This milestone,payment was triggered by the recent ... Phase II study with IMVAMUNE(R) in HIV infected ...
... 19 /PRNewswire-FirstCall/ - GeneNews Limited (TSX: GEN), a ... the early detection of diseases and personalized health ... Colorectal Cancer Advisory Board. Drs. Lawrence Cohen, Jeffrey ... Stein will advise GeneNews on clinical and patient ...
Cached Biology Technology:Synvista Therapeutics Announces 510(k) Submission for Its HAPTOCHEK(TM) Test Kit 2Bavarian Nordic Receives USD 25 Million Milestone Payment After Submission of Important IMVAMUNE(R) Data to The U.S. Health Authorities 2GeneNews appoints Canadian Colorectal Cancer Advisory Board 2GeneNews appoints Canadian Colorectal Cancer Advisory Board 3
A univariate (peak height or area) quantitative multi-component analysis package....
... The AquaMax DW4 liquid handling system ... thorough washing all in one instrument. The ... for dispensing and plate washing96-, 384- and ... microplate washing. AquaMax DW4 has been optimized ...
This free-standing laminar flow hood provides a horizontal flow of HEPA-filtered air to create a clean processing area. Air return slots along the front and side edges of the work area enhance system...
... series embodies all aspects of classical microscopy ... powerful Achromatic Super Contrast (ASC) objectives coupled ... this microscope combines flexibility and professional microscopy ... B1 series, the DM-B1 steps into the ...
Biology Products: