Navigation Links
A 'magnetic' solution to identify and kill tumors

Though a valuable weapon against cancerous tumors, radiation therapy often harms healthy tissue as it tries to kill malignant cells. Now, Prof. Israel Gannot of Tel Aviv University's Department of Biomedical Engineering is developing a new way to destroy tumors with fewer side effects and minimal damage to surrounding tissue.

His innovative method, soon to be published in the journal Nanomedicine, uses heat to kill the tumor cells but leaves surrounding healthy tissue intact. Using specific biomarkers attached to individual tumors, Prof. Gannot's special mixture of nano-particles and antibodies locates and binds to the tumor itself.

"Once the nano-particles bind to the tumor, we excite them with an external magnetic field, and they begin to heat very specifically and locally," says Prof. Gannot. The magnetic field is manipulated to create a targeted rise in temperature, and it is this directed heat elevation which kills the tumors, he says.

The treatment has been proven effective against epithelial cancers, which can develop in almost any area of the body, such as the breast or lung. By using a special feedback process, also developed in his laboratory, the process can be optimized for individual treatment.

A cure without casualty

The specialized cocktail of nano-particles and antibodies is administered safely and simply, through topical local injection or injection into the blood stream. As an added benefit, the mixture washes out of the body without leaving a trace, minimizing side effects.

If clinical trials are successful, the technique may become a mainstay of patient care. The nano-particles themselves are already FDA-approved, and according to Prof. Gannot, the method is effective almost any type of tumor, as long as its specific markers and its antibodies can be identified.

The countdown to demolition

In addition to being minimally invasive, this treatment boasts sheer speed. It can be applied during an out-patient procedure ― the entire technique lasts only six hours ― which allows patients to recuperate in the comfort of their own homes.

Prof. Gannot is currently applying his technique to cell lines and to ex vivo tissues and tissue-like substitutes in his lab, and plans to start in vivo experiments by next year.


Contact: George Hunka
American Friends of Tel Aviv University

Related biology news :

1. Louisiana Tech professor, researcher receives patent for electromagnetic technology
2. Researchers develop drug delivery system using nanoparticles triggered by electromagnetic field
3. Nuclear magnetic resonance aids in drug design
4. Texas Childrens Cancer Center first in Texas to magnetically lengthen nine-year-olds leg as she grows
5. Magnetic nanoparticles show promise for combating human cancer
6. Magnetic nanotags spot cancer in mice earlier than methods now in clinical use
7. Magnetic nano-shepherds organize cells
8. Magnetic nanoparticles navigate therapeutic genes through the body
9. Electromagnetic phantom exorcises specters of metal detector tests
10. Caltech geobiologists discover unique magnetic death star fossil
11. DigitalPersona Delivers New Centrally-Managed Solution for Notebook Data Protection and Remote Access Security
Post Your Comments:
(Date:4/24/2017)... , April 24, 2017 ... and partner with  Identity Strategy Partners, LLP (IdSP) ... "With or without President Trump,s March 6, 2017 ... Terrorist Entry , refugee vetting can be instilled with ... resettlement. (Right now, all refugee applications are suspended ...
(Date:4/17/2017)... Florida , April 17, 2017 NXT-ID, ... technology company, announces the filing of its 2016 Annual Report on ... and Exchange Commission. ... on Form 10-K is available in the Investor Relations section of ... as on the SEC,s website at . ...
(Date:4/11/2017)... 11, 2017 Crossmatch®, a globally-recognized leader ... today announced that it has been awarded a ... Activity (IARPA) to develop next-generation Presentation Attack Detection ... "Innovation has been a driving force within Crossmatch ... allow us to innovate and develop new technologies ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ... October 11, 2017 , ... ... and pregnancy rates in frozen and fresh in vitro fertilization (IVF) ... maternal age to IVF success. , After comparing the results from the fresh ...
(Date:10/10/2017)... ... ... Dr. Bob Harman, founder and CEO of VetStem Biopharma, Inc. spent ... entitled “Stem Cells and Their Regenerative Powers,” was held on August 31st, 2017 ... joined by two human doctors: Peter B. Hanson, M.D., Chief of Orthopedic Surgery, Grossmont ...
(Date:10/9/2017)... DIEGO , Oct. 9, 2017  BioTech ... biological mechanism by which its ProCell stem cell ... critical limb ischemia.  The Company, demonstrated that treatment ... amount of limbs saved as compared to standard ... the molecule HGF resulted in reduction of therapeutic ...
(Date:10/7/2017)... ... October 06, 2017 , ... ... instruments and applications consulting for microscopy and surface analysis, Nanoscience Instruments is ... Nanoscience Analytical offers a broad range of contract analysis services for advanced ...
Breaking Biology Technology: