Navigation Links
A magnetic nanoparticles-based method for DNA extraction from the saliva after stroke
Date:12/24/2013

C677T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene is a risk factor for stroke. Studies have report a higher C677T homozygosity frequency in Chinese than in Europeans. Usually, the detection of genetic diseases is rather complicated on a large scale owing to the invasive sampling and a cumbersome DNA extraction process. In a study by Dr. Li Yi and team from Peking University Shenzhen Hospital in China, DNA from stroke patients and healthy controls was extracted from the saliva using a magnetic nanoparticles-based method and from the blood using conventional methods. Real-time PCR results revealed that the C677T polymorphism was genotyped by PCR using DNA extracted from both saliva and blood samples. The genotype results were confirmed by gene sequencing, and results for saliva and blood samples were consistent. Therefore, this noninvasive magnetic nanoparticles-based method using saliva samples could be used to screen for the MTHFR C677T polymorphism in target populations. This study was published in the Neural Regeneration Research (Vol. 8, No. 32, 2013).


'/>"/>

Contact: Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
Source:Eurekalert  

Page: 1

Related biology news :

1. Tickling the brain with magnetic stimulation improves memory in schizophrenia
2. Artificial atoms allow for magnetic resonance on individual cells
3. Magnetic map guides salmon home
4. Salmon may use magnetic field as a navigational aid
5. First evidence of fish sensing geomagnetic fields from a Czech Christmas market
6. Video-article shows how to purify magnetic bacteria
7. The magnetic sense
8. Novel method could help bring cancer biomarkers to clinic
9. New method of DNA editing allows synthetic biologists to unlock secrets of a bacterial genome
10. New method for stabilizing hemoglobin could lead to stable vaccines, artificial blood
11. SU biologist develops method for monitoring shipping noise in dolphin habitat
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
A magnetic nanoparticles-based method for DNA extraction from the saliva after stroke
(Date:11/30/2016)... , Nov. 30, 2016 Not many of us realize that we spend ... recovery so we need to do it well. Inadequate sleep levels have been found ... pressure, stroke, diabetes, and even cancer. Maybe now is the best time ... could help them to manage their sleep quality? Continue ... ...
(Date:11/29/2016)... VILNIUS, Lithuania , Nov. 29, 2016 ... high-precision biometric identification and object recognition technologies, ... kit (SDK) for fingerprint recognition solutions that ... extract a fingerprint template using less than ... used in compact devices that have limited ...
(Date:11/24/2016)... , Nov. 23, 2016 Cercacor today introduced ... and their trainers non-invasively measure hemoglobin, Oxygen ... Rate, and Respiration Rate in approximately 30 seconds. Smaller ... easy and immediate access to key data about their ... a training regimen. Hemoglobin carries oxygen ...
Breaking Biology News(10 mins):
(Date:12/6/2016)... ... December 06, 2016 , ... ... the world’s largest privately-held contract pharmaceutical development and manufacturing organisation, today ... biopharma outsourcing company combining a leading CRO and the industry’s only Contract ...
(Date:12/6/2016)... ... ... Discovering new clues to natural treatments that could allow our bodies to ... And searching for keys to our immune systems by studying parasite-resistant fish. These are ... Edith and Peter O’Donnell Awards by The Academy of Medicine, Engineering and ...
(Date:12/6/2016)... Fort Collins, Colorado (PRWEB) , ... December 06, ... ... developer of dynamic aqueous plasma technology platforms, announced today that the company has ... five-year Master Research and Development Agreement (MRDA) with the CSU Office of the ...
(Date:12/6/2016)... -- According to a new market research report "Microfluidics ... Application (Genomics, Proteomics, Capillary Electrophoresis, POC, Clinical, Environmental, Drug Delivery) - ... projected to reach USD 8.78 Billion by 2021 from USD 3.65 ... period (2016 to 2021). Continue Reading ... ...
Breaking Biology Technology: