Navigation Links
A low dose of caffeine when pregnant may damage the heart of offspring for a lifetime
Date:12/16/2008

A new study published online in The FASEB Journal shows that the equivalent of one dose of caffeine (just two cups of coffee) ingested during pregnancy may be enough to affect fetal heart development and then reduce heart function over the entire lifespan of the child. In addition, the researchers also found that this relatively minimal amount of exposure may lead to higher body fat among males, when compared to those who were not exposed to caffeine. Although the study was in mice, the biological cause and effect described in the research paper is plausible in humans.

According to Scott Rivkees, Yale's Associate Chair of Pediatric Research and a senior researcher on the study, "Our studies raise potential concerns about caffeine exposure during very early pregnancy, but further studies are necessary to evaluate caffeine's safety during pregnancy."

To reach their conclusion researchers studied four groups of pregnant mice under two sets of conditions for 48 hours. The first two groups were studied in "room air," with one group having been injected with caffeine and another injected with saline solution. The second two groups were studied under conditions where ambient oxygen levels were halved, with one group receiving caffeine and the other receiving saline solution. They found that under both circumstances, mice given caffeine produced embryos with a thinner layer of tissue separating some of the heart's chambers than the group that was not given caffeine.

The researchers then examined the mice born from these groups to determine what long-term effects, if any, caffeine had on the offspring. They found that all of the adult males exposed to caffeine as fetuses had an increase in body fat of about 20 percent, and decreased cardiac function of 35󈞒 percent when compared to mice not exposed to caffeine.

"Caffeine is everywhere: in what we drink, in what we eat, in pills that we use to relieve pain, and even i
'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Post-exercise caffeine helps muscles refuel
2. Mixing large doses of both acetaminophen painkiller and caffeine may increase risk of liver damage
3. Statin warning for pregnant women
4. Pregnant women with asthma can be more confident about some medicines
5. Eating eggs when pregnant affects breast cancer in offspring
6. Pregnant women consuming flaxseed oil have high risk of premature birth
7. Almost 7 million pregnant in sub-Saharan Africa infected with hookworms; at risk of anaemia
8. Pregnant mice block out unwelcome admirers to protect their pups
9. Too much or too little weight gain poses risks to pregnant mothers, babies
10. Extreme nausea and vomiting varies among pregnant women from different countries
11. Pregnant patients lose out in breast cancer treatment; a new approach is needed
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... POINT ROBERTS, Washington , January 20, 2015 ... sectors including technology and tech stocks, releases video from the ... pickpocket and security consultant Apollo Robbins . ... about the Wocket™ biometric smart wallet, a product of NXT-ID, ...
(Date:1/22/2015)... 2015 , Europe,s ... The European Patent Office to present a video retrospective of the ... be featured: Christofer Toumazou and Sophie Wilson   ... winners of the Award   Starting on 22 January ...
(Date:1/22/2015)... Inc. , a market leader of iris-based identity authentication solutions, ... the new role of Senior Vice President of Mobile and ... platforms and wearable solutions for EyeLock,s technologies. Gerber brings more ... industry to his role at EyeLock, with expertise in human ...
Breaking Biology News(10 mins):Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 2Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 3Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 2Ten Years of the European Inventor Award: A Retrospective Look at the Inventors and Ideas That Have Changed Our Lives 3EyeLock Names Steve Gerber as Senior Vice President of Mobile and Wearables 2
... PITTSBURGH, Feb. 4 Researchers at the University ... $5.6 million federal contract to pursue the continued development ... and small children with congenital or acquired heart disease. ... sophisticated technologies that have saved the lives of older ...
... that the hydrodynamic environment of fish can shape their physical ... Journal of Experimental Biology Web site, was sponsored by ... Catch a glimpse of a fish,s body shape, and you ... look as if they should outpace frilly reef fish and ...
... energy habits and provide immediate feedback on consumption could ... compromising comfort. The new energy-saving ,Wattbox, device is ... improvements supported by a 2.1 million grant from the ... As well as working with standard energy supplies, the ...
Cached Biology News:Pitt-led team gets $5.6 million contract for heart assist device for infants and toddlers 2Pitt-led team gets $5.6 million contract for heart assist device for infants and toddlers 3Research finds water movements can shape fish evolution 2Habit-learning device will lower energy bills under new clean energy cashback scheme 2
(Date:1/22/2015)... 2015 Selexis SA, a serial innovation ... Banks (RCBs) used for drug discovery to commercial manufacturing, ... include Next-Generation Sequencing (NGS) data packages. The ... manufacturing by ensuring the integrity of the gene, validation ...
(Date:1/22/2015)... Jan. 22, 2015   Cypher Genomics, Inc., ... (NASDAQ: SQNM ), the leading molecular ... next generation noninvasive prenatal tests (NIPT). Through this ... called Mantis™, to advance analysis of clinically-relevant fetal ...
(Date:1/22/2015)... PRINCETON, N.J. , Jan. 22, 2015  Derma ... tissue regeneration company focused on advanced wound care, ... from placental tissues, have been added to the ... announcement increases the opportunity for the AMNIOEXCEL® and ...
(Date:12/24/2014)... and NEW YORK , Dec. 24, ... company advancing patient care in critical areas, announced the closing ... stock, and warrants to purchase up to an aggregate 3,500,000 ... per share and $.01 per warrant.  The warrants have a ...
Breaking Biology Technology:Selexis Generated Research Cell Banks Now Fully Sequenced Using Next-Generation Sequencing 2Cypher Genomics and Sequenom Announce Development Agreement 2Cypher Genomics and Sequenom Announce Development Agreement 3Cypher Genomics and Sequenom Announce Development Agreement 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 2Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 3Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 4Derma Sciences Expands Access of its AMNIOTIC TISSUE Product Line with New Premier, Inc. Agreement 5PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 2PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 3
... DUBLIN and PHILADELPHIA , June 3, ... specialty biopharmaceutical company,announces that its subsidiary Shire LLC has filed a lawsuit ... Anchen Pharmaceuticals,Inc. and Anchen, Inc. (collectively "Anchen") for the infringement of U.S.,Patent ... patent). , , , ...
... , -Proceeds to support acceleration of CYT387 Phase II myelofibrosis study- , ... MISSISSAUGA, ON , June 3 ... raised approximately US$3.2 million through a non-brokered private placement of 2,500,000 ... at no discount to the closing price of the shares on the NYSE ...
... , , , ... Endpoints , , , ... Agency in,2010 , , , ... reproductive medicine, announces positive Phase III data from its,second pivotal study (PEARL I) for its lead product ...
Cached Biology Technology:INTUNIV(TM) - Shire Files Suit Against Anchen Pharmaceuticals, Inc. and Anchen, Inc. 2INTUNIV(TM) - Shire Files Suit Against Anchen Pharmaceuticals, Inc. and Anchen, Inc. 3YM BioSciences raises US$3.2 million in support of JAK 1/2 program 2YM BioSciences raises US$3.2 million in support of JAK 1/2 program 3YM BioSciences raises US$3.2 million in support of JAK 1/2 program 4PregLem Announces Positive Phase III Results for Esmya(TM) 2PregLem Announces Positive Phase III Results for Esmya(TM) 3PregLem Announces Positive Phase III Results for Esmya(TM) 4