Navigation Links
A low dose of caffeine when pregnant may damage the heart of offspring for a lifetime
Date:12/16/2008

A new study published online in The FASEB Journal shows that the equivalent of one dose of caffeine (just two cups of coffee) ingested during pregnancy may be enough to affect fetal heart development and then reduce heart function over the entire lifespan of the child. In addition, the researchers also found that this relatively minimal amount of exposure may lead to higher body fat among males, when compared to those who were not exposed to caffeine. Although the study was in mice, the biological cause and effect described in the research paper is plausible in humans.

According to Scott Rivkees, Yale's Associate Chair of Pediatric Research and a senior researcher on the study, "Our studies raise potential concerns about caffeine exposure during very early pregnancy, but further studies are necessary to evaluate caffeine's safety during pregnancy."

To reach their conclusion researchers studied four groups of pregnant mice under two sets of conditions for 48 hours. The first two groups were studied in "room air," with one group having been injected with caffeine and another injected with saline solution. The second two groups were studied under conditions where ambient oxygen levels were halved, with one group receiving caffeine and the other receiving saline solution. They found that under both circumstances, mice given caffeine produced embryos with a thinner layer of tissue separating some of the heart's chambers than the group that was not given caffeine.

The researchers then examined the mice born from these groups to determine what long-term effects, if any, caffeine had on the offspring. They found that all of the adult males exposed to caffeine as fetuses had an increase in body fat of about 20 percent, and decreased cardiac function of 35󈞒 percent when compared to mice not exposed to caffeine.

"Caffeine is everywhere: in what we drink, in what we eat, in pills that we use to relieve pain, and even i
'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

0

GOOD

Page: 1 2

Related biology news :

1. Post-exercise caffeine helps muscles refuel
2. Mixing large doses of both acetaminophen painkiller and caffeine may increase risk of liver damage
3. Statin warning for pregnant women
4. Pregnant women with asthma can be more confident about some medicines
5. Eating eggs when pregnant affects breast cancer in offspring
6. Pregnant women consuming flaxseed oil have high risk of premature birth
7. Almost 7 million pregnant in sub-Saharan Africa infected with hookworms; at risk of anaemia
8. Pregnant mice block out unwelcome admirers to protect their pups
9. Too much or too little weight gain poses risks to pregnant mothers, babies
10. Extreme nausea and vomiting varies among pregnant women from different countries
11. Pregnant patients lose out in breast cancer treatment; a new approach is needed

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/24/2009)... is opening new doors to understanding how sounds ...g of a marine mammal or if they hear it at all. ,...canners that NASA uses to detect flaws in the spac...owing scientists to peek inside the giant head of ...mensional replicas of a whale,s hearing anatomy us...
(Date:11/24/2009)... NEW YORK (November 24, 2009) -- The Wildlife Con...evealing that the last remaining population of Sib... to the rising tide of poaching and habitat loss. ...rm Russian officials of what needs to be done to p...t cat. , The report was released by...
(Date:11/23/2009)...research presents strong evidence that the "synerg...or traffic-related pollution and indoor endotoxin ...he other exposure alone. , Environmental healt...College of Medicine have shown that children expos...s and indoor endotoxin during early life are six t...
Breaking Biology News(10 mins):Rocket science leads to new whale discovery 2Report shows dramatic decline in Siberian tigers 2Exposure to both traffic, indoor pollutants puts some kids at higher risk for asthma later 2Herley Reports Fourth Quarter and Year End Results 59611 1Herley Reports Fourth Quarter and Year End Results 59611 2Herley Reports Fourth Quarter and Year End Results 59611 3Herley Reports Fourth Quarter and Year End Results 59611 4Herley Reports Fourth Quarter and Year End Results 59611 5Herley Reports Fourth Quarter and Year End Results 59611 6Herley Reports Fourth Quarter and Year End Results 59611 7Herley Reports Fourth Quarter and Year End Results 59611 8Herley Reports Fourth Quarter and Year End Results 59611 9Herley Reports Fourth Quarter and Year End Results 59611 10Herley Reports Fourth Quarter and Year End Results 59611 11Herley Reports Fourth Quarter and Year End Results 59611 12Powerhouses in the cell dismantled 14501 1Powerhouses in the cell dismantled 14501 2Nations RNs Hail Sen Frankens Support for Safe Patient Handling Measure 59607 1Nations RNs Hail Sen Frankens Support for Safe Patient Handling Measure 59607 2
...ds are emerging as sentinels of climate change, re...ave shown. One of the UK,s most damaging aphids ...found to be flying two weeks earlier for every 1C ...combined. This year, the first aphid was caught o...e 42-year average. This work is reported in BBSR...
...mous amounts of data are being generated in health...d other areas, but analyzing these massive and uns...icult. An emerging research field known as data an...untains of information to find and put together in...tute of Technology has received a five-year grant ...
...KEN, N.J. On July 29, 2008, enXco, an EDF Energie...se Agreement (PPA) was made with Stevens Institute...ltaic system in Hoboken, N.J. The solar photovolta...und-mounted fixed-tilt solar arrays. enXco will ow...rovide financing for the project under a multi-yea...
Other Biology News:Aphids are sentinels of climate change 2Grant supports emerging field of massive data analysis and visual analytics 2Grant supports emerging field of massive data analysis and visual analytics 3Grant supports emerging field of massive data analysis and visual analytics 4
(Date:11/27/2009)... A mechanised blue dye test alternativ...ng quality assurance one step closer for pharma-co...k testing machine developed by Sepha for use wi... in several local and global pharma-companies such...lity assurance and productivity improvements on th...
(Date:11/25/2009)... Ambassador to Speak at Economic Club o...a (Vocus) November 25, 2009 -- Ambassador to Speak...Appia, French Ambassador for International Investm...Agency ,To view a biography of David Appia go to ...ppia is available to meet with press to discuss re...
(Date:11/25/2009)..., NEW YORK, Nov. 25 Reportlinker...s available in its catalogue: ,, Brazil Bioeth... http://www.reportlinker.com/p0165503/Brazil-Bioet...,, Brazil Bioethanol Market Analysis and Foreca...des detailed analysis and forecasts of the global ...
(Date:11/24/2009)... Ambassador to also Visit Detroit , ... , , ,Who: David Appia, French Ambassador for Inte...Invest in France Agency, , , , ,What: Ambassador ...ecent pro-business initiatives adopted by France t...ic landscape for innovation and development., , ,W...
Breaking Biology Technology:Sepha's Blue Dye Test Alternative Brings ‘Complete Automation' To Pharma-Packaging Quality Assurance 2Sepha's Blue Dye Test Alternative Brings ‘Complete Automation' To Pharma-Packaging Quality Assurance 3French Ambassador for International Investment to Visit Toronto December 11 2Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 2Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 3Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 4Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 5Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 6Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 7Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 8Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 9Reportlinker Adds Brazil Bioethanol Market Analysis and Forecasts to 2013 10
...lthcare and MobileAccess announced an exclusive wo...ireless services on a common infrastructure, calle...headquartered in Vienna, Virginia, makes in-buildi...voice and data services and applications. The comp...00 businesses including hospitals, enterprises, pu...
...mised, our latest e-mail newsletter contains the m... readership has increased from around 30,000 visi...em sticking around to read more than a few stories..., ,Let me take a moment to thank everyone who has ...isnt until March 2 and were more than a third full...
...undry reported revenue up 86 percent and a narrowe...multimedia presentation hardware and software for ... 2005 was $8.3 million, compared to last year,s $4...et loss, a slight improvement over last year,s $5....e firm,s growth phase, which also involved increas...
Other Biology Technology:
Anti-FKHR, phospho (Thr24) / FKHRL1, phospho (Thr32) Antibody, Unconjugated from Cell Signaling Technology
Mouse Anti-Ricin communis Monoclonal Antibody, Unconjugated, Clone CP23 from Abcam
Kinase Buffer (10X) from Cell Signaling Technology
Goat Anti-Als2 Polyclonal Antibody, Unconjugated from Abcam
Biology Products: