Navigation Links
A lab rat -- created in the lab
Date:4/13/2010

It's illegal for health products with medical formulations to be accepted by the U.S. Food and Drug Administration without tests on animals ― a situation that has serious ethical and moral implications. New research in the field of tissue engineering by Prof. Amit Gefen of Tel Aviv University's Faculty of Engineering holds a promise that far fewer lab animals will be needed for the necessary experimental trials.

Dr. Gefen's research into fat cells, published in a recent issue of Tissue Engineering, has led him to conclude that the necessary tissue can be produced from fat, skin, bone and muscle cells. His breakthrough study could have hundreds of applications in the pharmaceutical and medical world.

"Drugs make our lives better, and basic science is needed to push new drugs through clinical trials. But there is no doubt that an untold number of animals are sacrificed in the laboratory setting both in basic research and in applied conditions when testing particular molecules," says Prof. Gefen, who heads TAU's Teaching Laboratory for Cell and Tissue Engineering. As a medical researcher himself, he was dependent on animal trials for testing new hypotheses he developed for living systems ― until recently.

A more efficient road to scientific research

Bridging the worlds of biology and engineering, Prof. Gefen is now using adult rat stem cells ― cells that can be stimulated to create skin, bone, fat and muscle tissue from an animal in a laboratory setting. In his own work on studying the mechanical properties of pressure ulcers, many tissue replications were needed. His new approach no longer requires the sacrifice of large numbers of animals. When an experiment is over, not one animal life has been lost.

The use of engineered tissues, says Prof. Gefen, may also be more scientifically efficient than using those from a living source. "The model we've created offers a very reliable
'/>"/>

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Smart orthopedic implants and self-fitting tissue scaffolding created by UMMS researchers
2. Alzheimers rat created for human research
3. New period of brain plasticity created with transplanted embryonic cells
4. MSU scientists unlock key enzyme using newly created cool method
5. 3-D kidney atlas created for researchers and physicians
6. Most extensive genetic resource for reef-building coral created
7. Nanodrop test tubes created with a flip of a switch
8. Needle-size device created to track tumors, radiation dose
9. Worlds largest marine protected area created in Pacific Ocean
10. Natural insecticide re-created in the lab
11. Newly created cancer stem cells could aid breast cancer research
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
A lab rat -- created in the lab
(Date:11/3/2014)... and preterm birth are linked to increased risk for ... the American College of Rheumatology (ACR) journal, Arthritis ... and pre-term babies were not at greater risk of ... According to the ACR, 27 million Americans over the ... of OA range from mild to severe and include ...
(Date:11/2/2014)... ORLEANS, LA (2 November 2014)—In support of a bold ... Bill & Melinda Gates Foundation today announced an award ... Malaria Vaccine Initiative (MVI) in building new vaccines that ... help realize the "accelerating to zero" agenda. Such vaccines ... what could be called an "immunological bed net." ...
(Date:11/2/2014)... bar and bump into a biologist . . . , ... nerd sketch, researchers have taken this premise and applied it ... meaning in the rising oceans of genomic data. , In ... genome-wide studies are publishing at a dizzying rate. The challenge ... from the noise (and there is no shortage of noise). ...
Breaking Biology News(10 mins):Preterm, low birth-weight babies may need new hips in adulthood 2New malaria vaccines to prevent infection and block transmission get a shot in the arm 2New malaria vaccines to prevent infection and block transmission get a shot in the arm 3New malaria vaccines to prevent infection and block transmission get a shot in the arm 4Mutant models 2Mutant models 3Mutant models 4
... spit out the bad. A new study from the Monell ... gatekeeper. The research shows that strong bitter taste in and ... of nausea and display a pattern of stomach activity characteristic ... of quality of life for many people, including pregnant women, ...
... booms, the science of making music, the impact of noise ... just some of the intriguing topics that will be presented ... (ASA). The meeting will take place May 23-27, ... The ASA offers complimentary press registration to bona fide working ...
... you don,t swallow it at allis enough to cause that ... according to a new study reported in the April 12th ... work shows that our body and our physiology anticipate the ... contain toxins or anti-nutrients," said Paul Breslin of the Monell ...
Cached Biology News:The nauseating taste of bitter 2The science of sound 2The science of sound 3The science of sound 4The science of sound 5The science of sound 6Bitterness induces nausea, swallowing not required 2
(Date:11/21/2014)... Nov. 20, 2014 /PRNewswire/ - BIOREM Inc. (TSXV: BRM) ("Biorem" or "the ... periods ended September 30, 2014.  Biorem,s complete 2014 third quarter financial ... Financial Summary:Three-months ended September 30, , Nine-months ... data) , 2014 , 2013 , ... , 5,281 , 6,715 , 14,476 ...
(Date:11/18/2014)... FL (PRWEB) November 17, 2014 ... point-of-care diagnostic tests – today announces its third ... and Prevention’s (CDC) Get Smart About Antibiotics Week ... Week is a national campaign designed to highlight ... health departments, and non-profit and for-profit partners to ...
(Date:11/18/2014)... 17, 2014 pH measurement and control ... the pharmaceutical, chemical, and food and beverage industries. But ... and how do pH sensors work? METTLER TOLEDO has ... in process industries with these questions and more. , ... in the process industries. The actual sensor, the pH ...
(Date:11/18/2014)... 18, 2014 Alanda Software, a ... Reporting solutions, announced today that a top tier ... Consummate Provider™ solution in both the U.S. and ... SaaS based, Data Quality remediation portal, designed to ... party Providers improve their ability to capture, transmit ...
Breaking Biology Technology:Biorem Reports Third Quarter Results 2Biorem Reports Third Quarter Results 3RPS Again Partners with the CDC in Support of the 2014 Get Smart About Antibiotics Week 2RPS Again Partners with the CDC in Support of the 2014 Get Smart About Antibiotics Week 3pH Guide from METTLER TOLEDO Explains Measurement, Theory and Practice of pH Applications 2Alanda Software Completes Successful Implementation of Global Data Quality & Vendor Management Solution for Top Tier Global Biopharmaceutical Company 2
... -- China-Biotics,Inc. (OTC Bulletin Board: CHBT) ("China-Biotics," "the ... research, development,marketing and distribution of probiotics products, today ... plant at Qing Pu, Shanghai., "The new ... the cornerstone of our,growth strategy. We have put ...
... drive solid ... earnings growth., ST. DAVID,S, Bermuda, May ... for the quarter ended,March 31, 2008. Revenue in the quarter ended March ... quarter. The primary,drivers of the increase in revenue were the net sales ...
... ... AI programs - ... TSX symbol: SBS, CALGARY, May 9 /PRNewswire-FirstCall/ - SemBioSys Genetics Inc.,(TSX:SBS), ... announced its,2008 first quarter operational and financial results., Highlights, - ...
Cached Biology Technology:China-Biotics, Inc. Completes Foundation for Its New Plant 2Warner Chilcott Reports Operating Results for the Quarter ended March 31, 2008 and Updates 2008 Full Year Guidance 2Warner Chilcott Reports Operating Results for the Quarter ended March 31, 2008 and Updates 2008 Full Year Guidance 3Warner Chilcott Reports Operating Results for the Quarter ended March 31, 2008 and Updates 2008 Full Year Guidance 4Warner Chilcott Reports Operating Results for the Quarter ended March 31, 2008 and Updates 2008 Full Year Guidance 5Warner Chilcott Reports Operating Results for the Quarter ended March 31, 2008 and Updates 2008 Full Year Guidance 6Warner Chilcott Reports Operating Results for the Quarter ended March 31, 2008 and Updates 2008 Full Year Guidance 7Warner Chilcott Reports Operating Results for the Quarter ended March 31, 2008 and Updates 2008 Full Year Guidance 8Warner Chilcott Reports Operating Results for the Quarter ended March 31, 2008 and Updates 2008 Full Year Guidance 9Warner Chilcott Reports Operating Results for the Quarter ended March 31, 2008 and Updates 2008 Full Year Guidance 10Warner Chilcott Reports Operating Results for the Quarter ended March 31, 2008 and Updates 2008 Full Year Guidance 11Warner Chilcott Reports Operating Results for the Quarter ended March 31, 2008 and Updates 2008 Full Year Guidance 12Warner Chilcott Reports Operating Results for the Quarter ended March 31, 2008 and Updates 2008 Full Year Guidance 13Warner Chilcott Reports Operating Results for the Quarter ended March 31, 2008 and Updates 2008 Full Year Guidance 14Warner Chilcott Reports Operating Results for the Quarter ended March 31, 2008 and Updates 2008 Full Year Guidance 15Warner Chilcott Reports Operating Results for the Quarter ended March 31, 2008 and Updates 2008 Full Year Guidance 16Warner Chilcott Reports Operating Results for the Quarter ended March 31, 2008 and Updates 2008 Full Year Guidance 17SemBioSys announces first quarter 2008 financial and operational results 2SemBioSys announces first quarter 2008 financial and operational results 3SemBioSys announces first quarter 2008 financial and operational results 4SemBioSys announces first quarter 2008 financial and operational results 5SemBioSys announces first quarter 2008 financial and operational results 6SemBioSys announces first quarter 2008 financial and operational results 7SemBioSys announces first quarter 2008 financial and operational results 8SemBioSys announces first quarter 2008 financial and operational results 9SemBioSys announces first quarter 2008 financial and operational results 10SemBioSys announces first quarter 2008 financial and operational results 11SemBioSys announces first quarter 2008 financial and operational results 12
... Ion Channel Cell Lines ,High Quality, Functionally-Validated, ... are well known for having a critical ... consequently have a key function in pain, ... ion channels have been investigated in therapeutic ...
... Channel Cell Lines ,High Quality, Functionally-Validated, Ion ... well known for having a critical role ... have a key function in pain, CNS ... channels have been investigated in therapeutic areas, ...
Mouse monoclonal antibody raised against a full length recombinant SLC25A11. NCBI Entrez Gene ID = SLC25A11...
... antibody raised against a partial ... Immunogen: TOPORS (NP_005793, 98 ... recombinant protein with GST tag. ... NM_005802 ...
Biology Products: